| Full name: BBSome interacting protein 1 | Alias Symbol: bA348N5.3|BBIP10|BBS18 | ||
| Type: protein-coding gene | Cytoband: 10q25.2 | ||
| Entrez ID: 92482 | HGNC ID: HGNC:28093 | Ensembl Gene: ENSG00000214413 | OMIM ID: 613605 |
| Drug and gene relationship at DGIdb | |||
Expression of BBIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BBIP1 | 92482 | 228993_s_at | -1.2404 | 0.0861 | |
| GSE20347 | BBIP1 | 92482 | 213224_s_at | -1.4242 | 0.0000 | |
| GSE23400 | BBIP1 | 92482 | 213224_s_at | -0.5344 | 0.0000 | |
| GSE26886 | BBIP1 | 92482 | 228993_s_at | -0.5283 | 0.0898 | |
| GSE29001 | BBIP1 | 92482 | 213220_at | -0.0599 | 0.8276 | |
| GSE38129 | BBIP1 | 92482 | 213220_at | 0.0840 | 0.6034 | |
| GSE45670 | BBIP1 | 92482 | 228993_s_at | -0.8564 | 0.0053 | |
| GSE53622 | BBIP1 | 92482 | 46549 | -0.0695 | 0.3311 | |
| GSE53624 | BBIP1 | 92482 | 46549 | 0.1539 | 0.0120 | |
| GSE63941 | BBIP1 | 92482 | 213220_at | -0.0993 | 0.8325 | |
| GSE77861 | BBIP1 | 92482 | 228993_s_at | -1.3493 | 0.0194 | |
| GSE97050 | BBIP1 | 92482 | A_33_P3316983 | -0.0871 | 0.7535 | |
| SRP007169 | BBIP1 | 92482 | RNAseq | 0.4322 | 0.3565 | |
| SRP008496 | BBIP1 | 92482 | RNAseq | 0.2154 | 0.5566 | |
| SRP064894 | BBIP1 | 92482 | RNAseq | 0.0292 | 0.8275 | |
| SRP133303 | BBIP1 | 92482 | RNAseq | -0.1494 | 0.4243 | |
| SRP159526 | BBIP1 | 92482 | RNAseq | 0.1071 | 0.7294 | |
| SRP193095 | BBIP1 | 92482 | RNAseq | -0.1322 | 0.2253 | |
| SRP219564 | BBIP1 | 92482 | RNAseq | -0.0461 | 0.8837 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by BBIP1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of BBIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BBIP1 | 92482 | 1 | 9 | 20 | |
| GSE20123 | BBIP1 | 92482 | 1 | 8 | 21 | |
| GSE43470 | BBIP1 | 92482 | 0 | 7 | 36 | |
| GSE46452 | BBIP1 | 92482 | 0 | 11 | 48 | |
| GSE47630 | BBIP1 | 92482 | 2 | 14 | 24 | |
| GSE54993 | BBIP1 | 92482 | 8 | 0 | 62 | |
| GSE54994 | BBIP1 | 92482 | 1 | 10 | 42 | |
| GSE60625 | BBIP1 | 92482 | 0 | 0 | 11 | |
| GSE74703 | BBIP1 | 92482 | 0 | 5 | 31 | |
| GSE74704 | BBIP1 | 92482 | 1 | 4 | 15 | |
| TCGA | BBIP1 | 92482 | 4 | 29 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of BBIP1:
Generating mutation plots.
Highly correlated genes for BBIP1:
Showing top 20/889 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BBIP1 | TIFA | 0.808435 | 4 | 0 | 4 |
| BBIP1 | ZYG11B | 0.779704 | 3 | 0 | 3 |
| BBIP1 | COX7B | 0.778959 | 3 | 0 | 3 |
| BBIP1 | LRRFIP2 | 0.772737 | 7 | 0 | 7 |
| BBIP1 | FBXW5 | 0.769982 | 3 | 0 | 3 |
| BBIP1 | BRK1 | 0.769137 | 4 | 0 | 4 |
| BBIP1 | STXBP5 | 0.767478 | 5 | 0 | 5 |
| BBIP1 | PPP2R5C | 0.759996 | 3 | 0 | 3 |
| BBIP1 | EPB41L3 | 0.756082 | 6 | 0 | 6 |
| BBIP1 | ALDH9A1 | 0.754916 | 6 | 0 | 5 |
| BBIP1 | THUMPD3 | 0.751427 | 3 | 0 | 3 |
| BBIP1 | MRPS36 | 0.74902 | 5 | 0 | 5 |
| BBIP1 | USO1 | 0.748434 | 7 | 0 | 7 |
| BBIP1 | UBL3 | 0.747488 | 6 | 0 | 5 |
| BBIP1 | LRRK2 | 0.745037 | 4 | 0 | 4 |
| BBIP1 | NAGK | 0.742218 | 6 | 0 | 6 |
| BBIP1 | FBXL5 | 0.741296 | 7 | 0 | 7 |
| BBIP1 | STX12 | 0.738258 | 7 | 0 | 7 |
| BBIP1 | CCNG2 | 0.735853 | 7 | 0 | 6 |
| BBIP1 | C9orf85 | 0.7329 | 4 | 0 | 4 |
For details and further investigation, click here
