| Full name: zinc finger protein 257 | Alias Symbol: BMZF-4 | ||
| Type: protein-coding gene | Cytoband: 19p12 | ||
| Entrez ID: 113835 | HGNC ID: HGNC:13498 | Ensembl Gene: ENSG00000197134 | OMIM ID: 606957 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF257:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF257 | 113835 | 210697_at | 0.0994 | 0.8980 | |
| GSE20347 | ZNF257 | 113835 | 210697_at | 0.0734 | 0.5886 | |
| GSE23400 | ZNF257 | 113835 | 210697_at | -0.0240 | 0.2849 | |
| GSE26886 | ZNF257 | 113835 | 210697_at | -0.0616 | 0.5065 | |
| GSE29001 | ZNF257 | 113835 | 210697_at | -0.0543 | 0.5713 | |
| GSE38129 | ZNF257 | 113835 | 210697_at | 0.0186 | 0.8603 | |
| GSE45670 | ZNF257 | 113835 | 210697_at | -0.1685 | 0.0703 | |
| GSE53622 | ZNF257 | 113835 | 89570 | -0.6220 | 0.0005 | |
| GSE53624 | ZNF257 | 113835 | 89570 | -1.3585 | 0.0000 | |
| GSE63941 | ZNF257 | 113835 | 210697_at | -0.1404 | 0.5107 | |
| GSE77861 | ZNF257 | 113835 | 210697_at | -0.0030 | 0.9748 | |
| GSE97050 | ZNF257 | 113835 | A_24_P298545 | -0.2960 | 0.2918 | |
| SRP133303 | ZNF257 | 113835 | RNAseq | -0.5704 | 0.0132 | |
| SRP159526 | ZNF257 | 113835 | RNAseq | -1.7158 | 0.0069 | |
| SRP193095 | ZNF257 | 113835 | RNAseq | -0.0599 | 0.8288 | |
| SRP219564 | ZNF257 | 113835 | RNAseq | 0.1106 | 0.8600 | |
| TCGA | ZNF257 | 113835 | RNAseq | -0.9668 | 0.0417 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZNF257 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF257:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF257 | 113835 | 5 | 4 | 21 | |
| GSE20123 | ZNF257 | 113835 | 5 | 2 | 23 | |
| GSE43470 | ZNF257 | 113835 | 2 | 6 | 35 | |
| GSE46452 | ZNF257 | 113835 | 47 | 1 | 11 | |
| GSE47630 | ZNF257 | 113835 | 7 | 7 | 26 | |
| GSE54993 | ZNF257 | 113835 | 17 | 3 | 50 | |
| GSE54994 | ZNF257 | 113835 | 6 | 13 | 34 | |
| GSE60625 | ZNF257 | 113835 | 9 | 0 | 2 | |
| GSE74703 | ZNF257 | 113835 | 2 | 4 | 30 | |
| GSE74704 | ZNF257 | 113835 | 2 | 2 | 16 | |
| TCGA | ZNF257 | 113835 | 17 | 13 | 66 |
Total number of gains: 119; Total number of losses: 55; Total Number of normals: 314.
Somatic mutations of ZNF257:
Generating mutation plots.
Highly correlated genes for ZNF257:
Showing top 20/110 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF257 | ERP27 | 0.787398 | 3 | 0 | 3 |
| ZNF257 | SSBP3 | 0.740895 | 3 | 0 | 3 |
| ZNF257 | SHPRH | 0.731507 | 3 | 0 | 3 |
| ZNF257 | ALG6 | 0.71284 | 3 | 0 | 3 |
| ZNF257 | GDF9 | 0.681499 | 3 | 0 | 3 |
| ZNF257 | LCOR | 0.680401 | 3 | 0 | 3 |
| ZNF257 | ADH1A | 0.669546 | 3 | 0 | 3 |
| ZNF257 | ZNF701 | 0.667974 | 3 | 0 | 3 |
| ZNF257 | SLC25A40 | 0.663561 | 4 | 0 | 3 |
| ZNF257 | ARIH1 | 0.66148 | 3 | 0 | 3 |
| ZNF257 | MTMR12 | 0.658853 | 3 | 0 | 3 |
| ZNF257 | ZNF749 | 0.64982 | 3 | 0 | 3 |
| ZNF257 | GYG2 | 0.649652 | 4 | 0 | 3 |
| ZNF257 | BIVM | 0.638883 | 3 | 0 | 3 |
| ZNF257 | IFT46 | 0.63382 | 3 | 0 | 3 |
| ZNF257 | TNP2 | 0.633222 | 3 | 0 | 3 |
| ZNF257 | ATXN3L | 0.632369 | 3 | 0 | 3 |
| ZNF257 | OTUD7B | 0.629652 | 4 | 0 | 3 |
| ZNF257 | ZNF780B | 0.627869 | 4 | 0 | 4 |
| ZNF257 | TCTEX1D2 | 0.627791 | 3 | 0 | 3 |
For details and further investigation, click here
