| Full name: growth differentiation factor 9 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 2661 | HGNC ID: HGNC:4224 | Ensembl Gene: ENSG00000164404 | OMIM ID: 601918 |
| Drug and gene relationship at DGIdb | |||
Expression of GDF9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GDF9 | 2661 | 221314_at | 0.0924 | 0.7275 | |
| GSE20347 | GDF9 | 2661 | 221314_at | 0.0934 | 0.3307 | |
| GSE23400 | GDF9 | 2661 | 221314_at | -0.0459 | 0.3583 | |
| GSE26886 | GDF9 | 2661 | 221314_at | 0.1541 | 0.2759 | |
| GSE29001 | GDF9 | 2661 | 221314_at | -0.0423 | 0.7934 | |
| GSE38129 | GDF9 | 2661 | 221314_at | 0.0247 | 0.8269 | |
| GSE45670 | GDF9 | 2661 | 221314_at | 0.0946 | 0.2443 | |
| GSE53622 | GDF9 | 2661 | 48504 | 0.2749 | 0.0001 | |
| GSE53624 | GDF9 | 2661 | 48504 | 0.3593 | 0.0000 | |
| GSE63941 | GDF9 | 2661 | 221314_at | 0.2681 | 0.0637 | |
| GSE77861 | GDF9 | 2661 | 221314_at | -0.0884 | 0.4646 | |
| GSE97050 | GDF9 | 2661 | A_23_P167585 | 0.1659 | 0.3822 | |
| SRP159526 | GDF9 | 2661 | RNAseq | 0.4651 | 0.3120 | |
| SRP219564 | GDF9 | 2661 | RNAseq | -0.1405 | 0.7353 | |
| TCGA | GDF9 | 2661 | RNAseq | -0.9418 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GDF9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GDF9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDF9 | 2661 | 1 | 11 | 18 | |
| GSE20123 | GDF9 | 2661 | 2 | 11 | 17 | |
| GSE43470 | GDF9 | 2661 | 2 | 9 | 32 | |
| GSE46452 | GDF9 | 2661 | 0 | 27 | 32 | |
| GSE47630 | GDF9 | 2661 | 0 | 21 | 19 | |
| GSE54993 | GDF9 | 2661 | 9 | 1 | 60 | |
| GSE54994 | GDF9 | 2661 | 2 | 14 | 37 | |
| GSE60625 | GDF9 | 2661 | 0 | 0 | 11 | |
| GSE74703 | GDF9 | 2661 | 2 | 6 | 28 | |
| GSE74704 | GDF9 | 2661 | 1 | 5 | 14 | |
| TCGA | GDF9 | 2661 | 3 | 39 | 54 |
Total number of gains: 22; Total number of losses: 144; Total Number of normals: 322.
Somatic mutations of GDF9:
Generating mutation plots.
Highly correlated genes for GDF9:
Showing top 20/695 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDF9 | FLT3LG | 0.747583 | 3 | 0 | 3 |
| GDF9 | CAMTA1 | 0.746337 | 3 | 0 | 3 |
| GDF9 | FOXN2 | 0.739238 | 3 | 0 | 3 |
| GDF9 | SLC17A1 | 0.726457 | 4 | 0 | 4 |
| GDF9 | TMEM209 | 0.726146 | 4 | 0 | 4 |
| GDF9 | ATG10 | 0.718618 | 6 | 0 | 6 |
| GDF9 | CDYL2 | 0.718497 | 3 | 0 | 3 |
| GDF9 | MTAP | 0.718254 | 5 | 0 | 5 |
| GDF9 | DHX58 | 0.710221 | 3 | 0 | 3 |
| GDF9 | HHLA1 | 0.709398 | 5 | 0 | 5 |
| GDF9 | CCRL2 | 0.708603 | 3 | 0 | 3 |
| GDF9 | CBLN1 | 0.707068 | 4 | 0 | 4 |
| GDF9 | LRRC36 | 0.70516 | 4 | 0 | 3 |
| GDF9 | MRPL41 | 0.70449 | 4 | 0 | 4 |
| GDF9 | FCF1 | 0.70448 | 3 | 0 | 3 |
| GDF9 | NEU3 | 0.703829 | 5 | 0 | 4 |
| GDF9 | MED30 | 0.702268 | 3 | 0 | 3 |
| GDF9 | TOM1L1 | 0.699506 | 3 | 0 | 3 |
| GDF9 | TAOK1 | 0.698922 | 4 | 0 | 3 |
| GDF9 | THAP8 | 0.689477 | 3 | 0 | 3 |
For details and further investigation, click here
