| Full name: endoplasmic reticulum protein 27 | Alias Symbol: FLJ32115|ERp27|PDIA8 | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 121506 | HGNC ID: HGNC:26495 | Ensembl Gene: ENSG00000139055 | OMIM ID: 610642 |
| Drug and gene relationship at DGIdb | |||
Expression of ERP27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERP27 | 121506 | 227450_at | 0.6853 | 0.4339 | |
| GSE26886 | ERP27 | 121506 | 227450_at | 0.4932 | 0.4521 | |
| GSE45670 | ERP27 | 121506 | 227450_at | 1.3515 | 0.0029 | |
| GSE53622 | ERP27 | 121506 | 44493 | 0.2218 | 0.2798 | |
| GSE53624 | ERP27 | 121506 | 44493 | 0.1711 | 0.3663 | |
| GSE63941 | ERP27 | 121506 | 227450_at | 2.2888 | 0.2561 | |
| GSE77861 | ERP27 | 121506 | 227450_at | 0.0649 | 0.8527 | |
| GSE97050 | ERP27 | 121506 | A_23_P139687 | 0.0371 | 0.9335 | |
| SRP133303 | ERP27 | 121506 | RNAseq | -0.2358 | 0.4136 | |
| SRP159526 | ERP27 | 121506 | RNAseq | 0.8676 | 0.2596 | |
| TCGA | ERP27 | 121506 | RNAseq | -0.8461 | 0.0118 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ERP27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERP27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERP27 | 121506 | 6 | 2 | 22 | |
| GSE20123 | ERP27 | 121506 | 6 | 2 | 22 | |
| GSE43470 | ERP27 | 121506 | 9 | 4 | 30 | |
| GSE46452 | ERP27 | 121506 | 10 | 1 | 48 | |
| GSE47630 | ERP27 | 121506 | 14 | 1 | 25 | |
| GSE54993 | ERP27 | 121506 | 1 | 9 | 60 | |
| GSE54994 | ERP27 | 121506 | 10 | 2 | 41 | |
| GSE60625 | ERP27 | 121506 | 0 | 1 | 10 | |
| GSE74703 | ERP27 | 121506 | 9 | 3 | 24 | |
| GSE74704 | ERP27 | 121506 | 4 | 1 | 15 | |
| TCGA | ERP27 | 121506 | 41 | 5 | 50 |
Total number of gains: 110; Total number of losses: 31; Total Number of normals: 347.
Somatic mutations of ERP27:
Generating mutation plots.
Highly correlated genes for ERP27:
Showing top 20/168 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERP27 | FKTN | 0.809451 | 3 | 0 | 3 |
| ERP27 | ZNF322 | 0.808758 | 3 | 0 | 3 |
| ERP27 | NR2C2 | 0.788294 | 3 | 0 | 3 |
| ERP27 | ZNF257 | 0.787398 | 3 | 0 | 3 |
| ERP27 | FAM76B | 0.786833 | 3 | 0 | 3 |
| ERP27 | B3GALNT2 | 0.782493 | 3 | 0 | 3 |
| ERP27 | RBM4B | 0.776649 | 3 | 0 | 3 |
| ERP27 | ANGEL2 | 0.774483 | 3 | 0 | 3 |
| ERP27 | TYW1 | 0.773741 | 3 | 0 | 3 |
| ERP27 | TBRG4 | 0.767087 | 3 | 0 | 3 |
| ERP27 | TSPAN15 | 0.766206 | 3 | 0 | 3 |
| ERP27 | BIVM | 0.765466 | 3 | 0 | 3 |
| ERP27 | RAB1B | 0.761378 | 3 | 0 | 3 |
| ERP27 | GYG2 | 0.75016 | 3 | 0 | 3 |
| ERP27 | ZC3HAV1 | 0.749984 | 3 | 0 | 3 |
| ERP27 | SLC29A3 | 0.748556 | 3 | 0 | 3 |
| ERP27 | LRTOMT | 0.747176 | 3 | 0 | 3 |
| ERP27 | SP1 | 0.741373 | 3 | 0 | 3 |
| ERP27 | BAK1 | 0.741242 | 3 | 0 | 3 |
| ERP27 | MIS12 | 0.737825 | 3 | 0 | 3 |
For details and further investigation, click here
