| Full name: ariadne RBR E3 ubiquitin protein ligase 1 | Alias Symbol: HARI|HHARI|UBCH7BP|ARI | ||
| Type: protein-coding gene | Cytoband: 15q24.1 | ||
| Entrez ID: 25820 | HGNC ID: HGNC:689 | Ensembl Gene: ENSG00000166233 | OMIM ID: 605624 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARIH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARIH1 | 25820 | 201880_at | -0.2367 | 0.6026 | |
| GSE20347 | ARIH1 | 25820 | 201879_at | -0.2220 | 0.5448 | |
| GSE23400 | ARIH1 | 25820 | 201880_at | -0.3179 | 0.0002 | |
| GSE26886 | ARIH1 | 25820 | 201881_s_at | -0.0469 | 0.8871 | |
| GSE29001 | ARIH1 | 25820 | 201879_at | -0.3143 | 0.1469 | |
| GSE38129 | ARIH1 | 25820 | 201880_at | -0.2161 | 0.3146 | |
| GSE45670 | ARIH1 | 25820 | 201880_at | -0.3264 | 0.0115 | |
| GSE53622 | ARIH1 | 25820 | 17186 | -0.2425 | 0.0001 | |
| GSE53624 | ARIH1 | 25820 | 17186 | -0.2279 | 0.0010 | |
| GSE63941 | ARIH1 | 25820 | 201880_at | -0.0558 | 0.9083 | |
| GSE77861 | ARIH1 | 25820 | 201880_at | -0.3378 | 0.1551 | |
| GSE97050 | ARIH1 | 25820 | A_23_P401014 | -0.4804 | 0.1267 | |
| SRP007169 | ARIH1 | 25820 | RNAseq | -0.3217 | 0.4197 | |
| SRP008496 | ARIH1 | 25820 | RNAseq | -0.1099 | 0.6420 | |
| SRP064894 | ARIH1 | 25820 | RNAseq | -0.4798 | 0.0007 | |
| SRP133303 | ARIH1 | 25820 | RNAseq | 0.0489 | 0.7189 | |
| SRP159526 | ARIH1 | 25820 | RNAseq | -0.1703 | 0.5535 | |
| SRP193095 | ARIH1 | 25820 | RNAseq | -0.0607 | 0.4702 | |
| SRP219564 | ARIH1 | 25820 | RNAseq | -0.3560 | 0.2227 | |
| TCGA | ARIH1 | 25820 | RNAseq | -0.0339 | 0.4348 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARIH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARIH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARIH1 | 25820 | 8 | 0 | 22 | |
| GSE20123 | ARIH1 | 25820 | 8 | 0 | 22 | |
| GSE43470 | ARIH1 | 25820 | 4 | 6 | 33 | |
| GSE46452 | ARIH1 | 25820 | 3 | 7 | 49 | |
| GSE47630 | ARIH1 | 25820 | 8 | 10 | 22 | |
| GSE54993 | ARIH1 | 25820 | 5 | 6 | 59 | |
| GSE54994 | ARIH1 | 25820 | 5 | 8 | 40 | |
| GSE60625 | ARIH1 | 25820 | 4 | 4 | 3 | |
| GSE74703 | ARIH1 | 25820 | 4 | 3 | 29 | |
| GSE74704 | ARIH1 | 25820 | 4 | 0 | 16 | |
| TCGA | ARIH1 | 25820 | 12 | 15 | 69 |
Total number of gains: 65; Total number of losses: 59; Total Number of normals: 364.
Somatic mutations of ARIH1:
Generating mutation plots.
Highly correlated genes for ARIH1:
Showing top 20/358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARIH1 | AKIRIN1 | 0.799183 | 3 | 0 | 3 |
| ARIH1 | VDAC3 | 0.794924 | 3 | 0 | 3 |
| ARIH1 | EXOC4 | 0.768157 | 3 | 0 | 3 |
| ARIH1 | TMEM218 | 0.766115 | 3 | 0 | 3 |
| ARIH1 | TUBGCP4 | 0.766059 | 3 | 0 | 3 |
| ARIH1 | NDUFB8 | 0.755414 | 3 | 0 | 3 |
| ARIH1 | VDAC2 | 0.752764 | 4 | 0 | 4 |
| ARIH1 | RPL14 | 0.75209 | 3 | 0 | 3 |
| ARIH1 | RALA | 0.74583 | 3 | 0 | 3 |
| ARIH1 | CTPS2 | 0.723943 | 4 | 0 | 4 |
| ARIH1 | SWAP70 | 0.722358 | 4 | 0 | 3 |
| ARIH1 | CTTNBP2NL | 0.72011 | 4 | 0 | 3 |
| ARIH1 | FAM98B | 0.713266 | 4 | 0 | 3 |
| ARIH1 | NDN | 0.712646 | 4 | 0 | 3 |
| ARIH1 | PTRHD1 | 0.708018 | 3 | 0 | 3 |
| ARIH1 | AP3M1 | 0.706719 | 4 | 0 | 4 |
| ARIH1 | GLUD2 | 0.705941 | 4 | 0 | 3 |
| ARIH1 | ZNF425 | 0.700141 | 3 | 0 | 3 |
| ARIH1 | SNAPC5 | 0.69826 | 4 | 0 | 4 |
| ARIH1 | RPS24 | 0.696794 | 4 | 0 | 3 |
For details and further investigation, click here
