| Full name: zinc finger protein 473 | Alias Symbol: KIAA1141|DKFZP434N043|HZFP100 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 25888 | HGNC ID: HGNC:23239 | Ensembl Gene: ENSG00000142528 | OMIM ID: 617908 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF473:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF473 | 25888 | 213124_at | 0.5497 | 0.3489 | |
| GSE20347 | ZNF473 | 25888 | 213130_at | 0.2113 | 0.0105 | |
| GSE23400 | ZNF473 | 25888 | 213130_at | 0.0242 | 0.6136 | |
| GSE26886 | ZNF473 | 25888 | 213130_at | 0.1278 | 0.3607 | |
| GSE29001 | ZNF473 | 25888 | 213130_at | 0.1859 | 0.3998 | |
| GSE38129 | ZNF473 | 25888 | 213130_at | 0.1936 | 0.0605 | |
| GSE45670 | ZNF473 | 25888 | 213130_at | 0.3000 | 0.0367 | |
| GSE53622 | ZNF473 | 25888 | 81342 | 0.4675 | 0.0000 | |
| GSE53624 | ZNF473 | 25888 | 81342 | 0.6581 | 0.0000 | |
| GSE63941 | ZNF473 | 25888 | 213124_at | 0.8491 | 0.0642 | |
| GSE77861 | ZNF473 | 25888 | 213130_at | 0.0708 | 0.6319 | |
| GSE97050 | ZNF473 | 25888 | A_24_P941376 | 0.1133 | 0.6403 | |
| SRP007169 | ZNF473 | 25888 | RNAseq | 0.4676 | 0.4308 | |
| SRP008496 | ZNF473 | 25888 | RNAseq | 0.5674 | 0.1066 | |
| SRP064894 | ZNF473 | 25888 | RNAseq | 0.5177 | 0.0008 | |
| SRP133303 | ZNF473 | 25888 | RNAseq | 0.3646 | 0.0596 | |
| SRP159526 | ZNF473 | 25888 | RNAseq | 1.0228 | 0.0013 | |
| SRP193095 | ZNF473 | 25888 | RNAseq | 0.2813 | 0.0159 | |
| SRP219564 | ZNF473 | 25888 | RNAseq | 0.0953 | 0.7438 | |
| TCGA | ZNF473 | 25888 | RNAseq | -0.0148 | 0.8180 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF473 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF473:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF473 | 25888 | 4 | 4 | 22 | |
| GSE20123 | ZNF473 | 25888 | 4 | 3 | 23 | |
| GSE43470 | ZNF473 | 25888 | 5 | 11 | 27 | |
| GSE46452 | ZNF473 | 25888 | 45 | 1 | 13 | |
| GSE47630 | ZNF473 | 25888 | 10 | 6 | 24 | |
| GSE54993 | ZNF473 | 25888 | 17 | 4 | 49 | |
| GSE54994 | ZNF473 | 25888 | 4 | 14 | 35 | |
| GSE60625 | ZNF473 | 25888 | 9 | 0 | 2 | |
| GSE74703 | ZNF473 | 25888 | 5 | 7 | 24 | |
| GSE74704 | ZNF473 | 25888 | 4 | 1 | 15 | |
| TCGA | ZNF473 | 25888 | 14 | 18 | 64 |
Total number of gains: 121; Total number of losses: 69; Total Number of normals: 298.
Somatic mutations of ZNF473:
Generating mutation plots.
Highly correlated genes for ZNF473:
Showing top 20/721 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF473 | GTPBP6 | 0.801713 | 3 | 0 | 3 |
| ZNF473 | RCBTB1 | 0.786686 | 3 | 0 | 3 |
| ZNF473 | LYRM4 | 0.785725 | 4 | 0 | 4 |
| ZNF473 | VCP | 0.766721 | 3 | 0 | 3 |
| ZNF473 | KLHL21 | 0.753242 | 3 | 0 | 3 |
| ZNF473 | THADA | 0.748539 | 3 | 0 | 3 |
| ZNF473 | CTXN1 | 0.745407 | 3 | 0 | 3 |
| ZNF473 | LDLRAP1 | 0.741907 | 3 | 0 | 3 |
| ZNF473 | ZAP70 | 0.739992 | 3 | 0 | 3 |
| ZNF473 | SWT1 | 0.737043 | 3 | 0 | 3 |
| ZNF473 | FN3KRP | 0.72789 | 3 | 0 | 3 |
| ZNF473 | KHNYN | 0.726725 | 3 | 0 | 3 |
| ZNF473 | CLIP2 | 0.722776 | 3 | 0 | 3 |
| ZNF473 | NAA30 | 0.721003 | 3 | 0 | 3 |
| ZNF473 | FAM167B | 0.719719 | 3 | 0 | 3 |
| ZNF473 | FCHO1 | 0.718549 | 4 | 0 | 3 |
| ZNF473 | LPGAT1 | 0.716358 | 3 | 0 | 3 |
| ZNF473 | ZNF566 | 0.7161 | 3 | 0 | 3 |
| ZNF473 | RNF220 | 0.714599 | 3 | 0 | 3 |
| ZNF473 | CSTF2T | 0.710748 | 4 | 0 | 4 |
For details and further investigation, click here
