| Full name: KH and NYN domain containing | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 23351 | HGNC ID: HGNC:20166 | Ensembl Gene: ENSG00000100441 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KHNYN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KHNYN | 23351 | 212356_at | 0.3983 | 0.5209 | |
| GSE20347 | KHNYN | 23351 | 212356_at | -0.1151 | 0.5079 | |
| GSE23400 | KHNYN | 23351 | 212356_at | -0.0260 | 0.6080 | |
| GSE26886 | KHNYN | 23351 | 212356_at | -0.3211 | 0.1301 | |
| GSE29001 | KHNYN | 23351 | 212356_at | -0.0433 | 0.8764 | |
| GSE38129 | KHNYN | 23351 | 212356_at | -0.1313 | 0.2616 | |
| GSE45670 | KHNYN | 23351 | 212356_at | 0.2213 | 0.0628 | |
| GSE63941 | KHNYN | 23351 | 212356_at | 0.7447 | 0.0932 | |
| GSE77861 | KHNYN | 23351 | 212356_at | 0.3392 | 0.1516 | |
| GSE97050 | KHNYN | 23351 | A_24_P170763 | 0.0423 | 0.9041 | |
| SRP007169 | KHNYN | 23351 | RNAseq | 0.1711 | 0.6935 | |
| SRP008496 | KHNYN | 23351 | RNAseq | 0.0430 | 0.8828 | |
| SRP064894 | KHNYN | 23351 | RNAseq | -0.0317 | 0.8122 | |
| SRP133303 | KHNYN | 23351 | RNAseq | 0.0099 | 0.9626 | |
| SRP159526 | KHNYN | 23351 | RNAseq | -0.3450 | 0.0626 | |
| SRP193095 | KHNYN | 23351 | RNAseq | -0.3334 | 0.0242 | |
| SRP219564 | KHNYN | 23351 | RNAseq | -0.1624 | 0.6195 | |
| TCGA | KHNYN | 23351 | RNAseq | -0.1503 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KHNYN expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KHNYN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KHNYN | 23351 | 8 | 3 | 19 | |
| GSE20123 | KHNYN | 23351 | 8 | 3 | 19 | |
| GSE43470 | KHNYN | 23351 | 8 | 2 | 33 | |
| GSE46452 | KHNYN | 23351 | 16 | 2 | 41 | |
| GSE47630 | KHNYN | 23351 | 11 | 10 | 19 | |
| GSE54993 | KHNYN | 23351 | 3 | 11 | 56 | |
| GSE54994 | KHNYN | 23351 | 18 | 5 | 30 | |
| GSE60625 | KHNYN | 23351 | 0 | 2 | 9 | |
| GSE74703 | KHNYN | 23351 | 7 | 2 | 27 | |
| GSE74704 | KHNYN | 23351 | 3 | 2 | 15 | |
| TCGA | KHNYN | 23351 | 28 | 12 | 56 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of KHNYN:
Generating mutation plots.
Highly correlated genes for KHNYN:
Showing top 20/260 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KHNYN | GLE1 | 0.813666 | 3 | 0 | 3 |
| KHNYN | SNRNP200 | 0.809294 | 3 | 0 | 3 |
| KHNYN | ZNF787 | 0.802628 | 3 | 0 | 3 |
| KHNYN | MRFAP1L1 | 0.782352 | 3 | 0 | 3 |
| KHNYN | LCAT | 0.771741 | 3 | 0 | 3 |
| KHNYN | MED15 | 0.771087 | 3 | 0 | 3 |
| KHNYN | CRKL | 0.766885 | 3 | 0 | 3 |
| KHNYN | ALG8 | 0.766865 | 3 | 0 | 3 |
| KHNYN | WBP4 | 0.765945 | 3 | 0 | 3 |
| KHNYN | C14orf119 | 0.764731 | 3 | 0 | 3 |
| KHNYN | CLASP1 | 0.758958 | 4 | 0 | 4 |
| KHNYN | GIT1 | 0.752689 | 3 | 0 | 3 |
| KHNYN | ARL10 | 0.750027 | 3 | 0 | 3 |
| KHNYN | ARL6IP6 | 0.747656 | 3 | 0 | 3 |
| KHNYN | ZNF280C | 0.747164 | 3 | 0 | 3 |
| KHNYN | SNRNP70 | 0.743744 | 3 | 0 | 3 |
| KHNYN | NAA30 | 0.737327 | 4 | 0 | 4 |
| KHNYN | SLC23A2 | 0.734476 | 3 | 0 | 3 |
| KHNYN | ATP2A3 | 0.732205 | 3 | 0 | 3 |
| KHNYN | TKT | 0.731403 | 3 | 0 | 3 |
For details and further investigation, click here
