LYRM4

 

Full name: LYR motif containing 4 Alias Symbol: CGI-203|ISD11
Type: protein-coding gene Cytoband: 6p25.1
Entrez ID: 57128 HGNC ID: HGNC:21365 Ensembl Gene: ENSG00000214113 OMIM ID: 613311
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of LYRM4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LYRM4 57128 218561_s_at 0.6115 0.1557
GSE20347 LYRM4 57128 218561_s_at 0.7162 0.0032
GSE23400 LYRM4 57128 218561_s_at 0.6224 0.0000
GSE26886 LYRM4 57128 218561_s_at 1.3051 0.0000
GSE29001 LYRM4 57128 218561_s_at 0.6689 0.0407
GSE38129 LYRM4 57128 218561_s_at 0.7005 0.0002
GSE45670 LYRM4 57128 218561_s_at 0.2898 0.2423
GSE53622 LYRM4 57128 7608 0.3758 0.0000
GSE53624 LYRM4 57128 7608 0.7369 0.0000
GSE63941 LYRM4 57128 218561_s_at 0.0825 0.8455
GSE77861 LYRM4 57128 218561_s_at 0.6584 0.0387
GSE97050 LYRM4 57128 A_23_P32328 0.0742 0.7327
SRP007169 LYRM4 57128 RNAseq 1.2316 0.0176
SRP008496 LYRM4 57128 RNAseq 1.0676 0.0004
SRP064894 LYRM4 57128 RNAseq 0.5824 0.0342
SRP133303 LYRM4 57128 RNAseq 0.3133 0.1063
SRP159526 LYRM4 57128 RNAseq 0.9403 0.0128
SRP193095 LYRM4 57128 RNAseq 0.1403 0.2347
SRP219564 LYRM4 57128 RNAseq 0.2624 0.4124
TCGA LYRM4 57128 RNAseq 0.1626 0.0219

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by LYRM4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LYRM4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LYRM4 57128 3 6 21
GSE20123 LYRM4 57128 3 6 21
GSE43470 LYRM4 57128 8 2 33
GSE46452 LYRM4 57128 1 10 48
GSE47630 LYRM4 57128 7 8 25
GSE54993 LYRM4 57128 1 1 68
GSE54994 LYRM4 57128 10 3 40
GSE60625 LYRM4 57128 0 1 10
GSE74703 LYRM4 57128 7 2 27
GSE74704 LYRM4 57128 2 2 16
TCGA LYRM4 57128 13 31 52

Total number of gains: 55; Total number of losses: 72; Total Number of normals: 361.  

 

Somatic mutations of LYRM4:

 

Generating mutation plots.

 

Highly correlated genes for LYRM4:

 

Showing top 20/1803 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LYRM4TAF1C0.794031303
LYRM4FCHO10.786523303
LYRM4ZNF4730.785725404
LYRM4TMEM2010.78507303
LYRM4MED260.782612303
LYRM4TNK10.781679303
LYRM4RNF1660.762118303
LYRM4COMMD70.746041404
LYRM4ZNF2340.741313303
LYRM4BIRC60.736551303
LYRM4ZNF5840.733269303
LYRM4RIOK10.728827807
LYRM4SLC39A30.727872404
LYRM4NOL70.72272412011
LYRM4ABCF10.72176410010
LYRM4NADK0.720313403
LYRM4LRRC580.719882504
LYRM4MRPL100.718419303
LYRM4CTU20.716544504
LYRM4PRELID20.70803403

For details and further investigation, click here