| Full name: valosin containing protein | Alias Symbol: IBMPFD|p97|CDC48|TERA | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 7415 | HGNC ID: HGNC:12666 | Ensembl Gene: ENSG00000165280 | OMIM ID: 601023 |
| Drug and gene relationship at DGIdb | |||
Expression of VCP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VCP | 7415 | 208649_s_at | 0.1681 | 0.6430 | |
| GSE20347 | VCP | 7415 | 208649_s_at | -0.0715 | 0.5686 | |
| GSE23400 | VCP | 7415 | 208649_s_at | 0.1986 | 0.0021 | |
| GSE26886 | VCP | 7415 | 208649_s_at | -0.4017 | 0.0287 | |
| GSE29001 | VCP | 7415 | 208648_at | 0.1953 | 0.3863 | |
| GSE38129 | VCP | 7415 | 208649_s_at | 0.1440 | 0.1903 | |
| GSE45670 | VCP | 7415 | 208649_s_at | 0.3377 | 0.0174 | |
| GSE53622 | VCP | 7415 | 7400 | 0.0370 | 0.5388 | |
| GSE53624 | VCP | 7415 | 7400 | 0.2761 | 0.0000 | |
| GSE63941 | VCP | 7415 | 208649_s_at | -0.0881 | 0.8215 | |
| GSE77861 | VCP | 7415 | 208649_s_at | 0.1035 | 0.7991 | |
| GSE97050 | VCP | 7415 | A_23_P83045 | 0.0801 | 0.7169 | |
| SRP007169 | VCP | 7415 | RNAseq | -0.6595 | 0.0752 | |
| SRP008496 | VCP | 7415 | RNAseq | -0.3617 | 0.1592 | |
| SRP064894 | VCP | 7415 | RNAseq | 0.3045 | 0.0224 | |
| SRP133303 | VCP | 7415 | RNAseq | 0.0002 | 0.9982 | |
| SRP159526 | VCP | 7415 | RNAseq | -0.2301 | 0.3289 | |
| SRP193095 | VCP | 7415 | RNAseq | -0.0300 | 0.8118 | |
| SRP219564 | VCP | 7415 | RNAseq | 0.5174 | 0.2342 | |
| TCGA | VCP | 7415 | RNAseq | 0.0505 | 0.2595 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VCP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VCP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VCP | 7415 | 3 | 13 | 14 | |
| GSE20123 | VCP | 7415 | 3 | 13 | 14 | |
| GSE43470 | VCP | 7415 | 3 | 10 | 30 | |
| GSE46452 | VCP | 7415 | 6 | 15 | 38 | |
| GSE47630 | VCP | 7415 | 1 | 20 | 19 | |
| GSE54993 | VCP | 7415 | 6 | 0 | 64 | |
| GSE54994 | VCP | 7415 | 6 | 12 | 35 | |
| GSE60625 | VCP | 7415 | 0 | 0 | 11 | |
| GSE74703 | VCP | 7415 | 2 | 7 | 27 | |
| GSE74704 | VCP | 7415 | 0 | 11 | 9 | |
| TCGA | VCP | 7415 | 16 | 44 | 36 |
Total number of gains: 46; Total number of losses: 145; Total Number of normals: 297.
Somatic mutations of VCP:
Generating mutation plots.
Highly correlated genes for VCP:
Showing top 20/165 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VCP | CATSPER1 | 0.787923 | 3 | 0 | 3 |
| VCP | ZNF473 | 0.766721 | 3 | 0 | 3 |
| VCP | SREBF2 | 0.764222 | 3 | 0 | 3 |
| VCP | HLA-E | 0.751686 | 3 | 0 | 3 |
| VCP | SNX12 | 0.75005 | 4 | 0 | 4 |
| VCP | RAB35 | 0.739679 | 3 | 0 | 3 |
| VCP | CD180 | 0.736008 | 3 | 0 | 3 |
| VCP | PRSS36 | 0.731844 | 3 | 0 | 3 |
| VCP | SLC29A1 | 0.730018 | 3 | 0 | 3 |
| VCP | CD3EAP | 0.728845 | 3 | 0 | 3 |
| VCP | DCXR | 0.727621 | 3 | 0 | 3 |
| VCP | CDK10 | 0.725691 | 3 | 0 | 3 |
| VCP | THAP8 | 0.719305 | 3 | 0 | 3 |
| VCP | GDI1 | 0.714962 | 3 | 0 | 3 |
| VCP | HECTD3 | 0.710975 | 3 | 0 | 3 |
| VCP | CELA3A | 0.709958 | 3 | 0 | 3 |
| VCP | EEFSEC | 0.700779 | 4 | 0 | 3 |
| VCP | NLRP3 | 0.700319 | 3 | 0 | 3 |
| VCP | SRRD | 0.698196 | 3 | 0 | 3 |
| VCP | MARS2 | 0.693879 | 3 | 0 | 3 |
For details and further investigation, click here
