| Full name: lysophosphatidylglycerol acyltransferase 1 | Alias Symbol: KIAA0205|FAM34A1|NET8 | ||
| Type: protein-coding gene | Cytoband: 1q32.3 | ||
| Entrez ID: 9926 | HGNC ID: HGNC:28985 | Ensembl Gene: ENSG00000123684 | OMIM ID: 610473 |
| Drug and gene relationship at DGIdb | |||
Expression of LPGAT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LPGAT1 | 9926 | 202651_at | 0.7365 | 0.0446 | |
| GSE20347 | LPGAT1 | 9926 | 202651_at | 0.5981 | 0.0221 | |
| GSE23400 | LPGAT1 | 9926 | 202651_at | 0.7421 | 0.0000 | |
| GSE26886 | LPGAT1 | 9926 | 202651_at | 1.0358 | 0.0155 | |
| GSE29001 | LPGAT1 | 9926 | 202651_at | 0.8179 | 0.0468 | |
| GSE38129 | LPGAT1 | 9926 | 202651_at | 0.6765 | 0.0017 | |
| GSE45670 | LPGAT1 | 9926 | 202651_at | 0.5021 | 0.0326 | |
| GSE53622 | LPGAT1 | 9926 | 66903 | 0.5353 | 0.0000 | |
| GSE53624 | LPGAT1 | 9926 | 66903 | 0.6060 | 0.0000 | |
| GSE63941 | LPGAT1 | 9926 | 202651_at | -0.7492 | 0.2006 | |
| GSE77861 | LPGAT1 | 9926 | 202651_at | 0.5639 | 0.1495 | |
| GSE97050 | LPGAT1 | 9926 | A_23_P46606 | 0.3997 | 0.1782 | |
| SRP007169 | LPGAT1 | 9926 | RNAseq | 0.5886 | 0.1022 | |
| SRP008496 | LPGAT1 | 9926 | RNAseq | 0.9870 | 0.0016 | |
| SRP064894 | LPGAT1 | 9926 | RNAseq | 0.6586 | 0.0002 | |
| SRP133303 | LPGAT1 | 9926 | RNAseq | 0.7211 | 0.0000 | |
| SRP159526 | LPGAT1 | 9926 | RNAseq | 1.0442 | 0.0000 | |
| SRP193095 | LPGAT1 | 9926 | RNAseq | 0.3244 | 0.0291 | |
| SRP219564 | LPGAT1 | 9926 | RNAseq | 0.7029 | 0.0416 | |
| TCGA | LPGAT1 | 9926 | RNAseq | 0.1285 | 0.0175 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LPGAT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LPGAT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LPGAT1 | 9926 | 11 | 0 | 19 | |
| GSE20123 | LPGAT1 | 9926 | 10 | 0 | 20 | |
| GSE43470 | LPGAT1 | 9926 | 7 | 0 | 36 | |
| GSE46452 | LPGAT1 | 9926 | 3 | 1 | 55 | |
| GSE47630 | LPGAT1 | 9926 | 15 | 0 | 25 | |
| GSE54993 | LPGAT1 | 9926 | 0 | 6 | 64 | |
| GSE54994 | LPGAT1 | 9926 | 13 | 0 | 40 | |
| GSE60625 | LPGAT1 | 9926 | 0 | 0 | 11 | |
| GSE74703 | LPGAT1 | 9926 | 7 | 0 | 29 | |
| GSE74704 | LPGAT1 | 9926 | 4 | 0 | 16 | |
| TCGA | LPGAT1 | 9926 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of LPGAT1:
Generating mutation plots.
Highly correlated genes for LPGAT1:
Showing top 20/1179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LPGAT1 | NF1 | 0.762391 | 3 | 0 | 3 |
| LPGAT1 | ACACA | 0.758692 | 3 | 0 | 3 |
| LPGAT1 | ZNF496 | 0.744684 | 4 | 0 | 4 |
| LPGAT1 | SSBP4 | 0.73404 | 3 | 0 | 3 |
| LPGAT1 | NEK3 | 0.730441 | 3 | 0 | 3 |
| LPGAT1 | CDC42EP4 | 0.725805 | 3 | 0 | 3 |
| LPGAT1 | RAB34 | 0.721468 | 3 | 0 | 3 |
| LPGAT1 | GPR107 | 0.71643 | 4 | 0 | 3 |
| LPGAT1 | ZNF473 | 0.716358 | 3 | 0 | 3 |
| LPGAT1 | NOM1 | 0.714852 | 4 | 0 | 4 |
| LPGAT1 | MRPL55 | 0.712251 | 4 | 0 | 3 |
| LPGAT1 | USPL1 | 0.71073 | 3 | 0 | 3 |
| LPGAT1 | ZC3HC1 | 0.710091 | 4 | 0 | 3 |
| LPGAT1 | UHMK1 | 0.706703 | 8 | 0 | 7 |
| LPGAT1 | KDM1B | 0.706132 | 3 | 0 | 3 |
| LPGAT1 | CENPBD1 | 0.705261 | 3 | 0 | 3 |
| LPGAT1 | TRIM59 | 0.698959 | 3 | 0 | 3 |
| LPGAT1 | CEP85 | 0.698916 | 3 | 0 | 3 |
| LPGAT1 | PKP4 | 0.698212 | 3 | 0 | 3 |
| LPGAT1 | MTFMT | 0.693065 | 3 | 0 | 3 |
For details and further investigation, click here
