| Full name: RCC1 and BTB domain containing protein 1 | Alias Symbol: FLJ10716|CLLD7|CLLL7 | ||
| Type: protein-coding gene | Cytoband: 13q14.2 | ||
| Entrez ID: 55213 | HGNC ID: HGNC:18243 | Ensembl Gene: ENSG00000136144 | OMIM ID: 607867 |
| Drug and gene relationship at DGIdb | |||
Expression of RCBTB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCBTB1 | 55213 | 218352_at | 0.4165 | 0.2322 | |
| GSE20347 | RCBTB1 | 55213 | 218352_at | 0.7449 | 0.0023 | |
| GSE23400 | RCBTB1 | 55213 | 218352_at | 0.5521 | 0.0000 | |
| GSE26886 | RCBTB1 | 55213 | 218352_at | 0.9653 | 0.0549 | |
| GSE29001 | RCBTB1 | 55213 | 218352_at | 0.6530 | 0.1319 | |
| GSE38129 | RCBTB1 | 55213 | 218352_at | 0.6404 | 0.0021 | |
| GSE45670 | RCBTB1 | 55213 | 218352_at | -0.0243 | 0.9512 | |
| GSE53622 | RCBTB1 | 55213 | 19677 | 0.4439 | 0.0002 | |
| GSE53624 | RCBTB1 | 55213 | 19677 | 0.4263 | 0.0001 | |
| GSE63941 | RCBTB1 | 55213 | 218352_at | -1.7548 | 0.0038 | |
| GSE77861 | RCBTB1 | 55213 | 218352_at | 1.2803 | 0.0300 | |
| GSE97050 | RCBTB1 | 55213 | A_23_P117163 | 0.3487 | 0.2345 | |
| SRP007169 | RCBTB1 | 55213 | RNAseq | 1.2502 | 0.0192 | |
| SRP008496 | RCBTB1 | 55213 | RNAseq | 1.5837 | 0.0000 | |
| SRP064894 | RCBTB1 | 55213 | RNAseq | 0.8238 | 0.0038 | |
| SRP133303 | RCBTB1 | 55213 | RNAseq | 0.0935 | 0.2579 | |
| SRP159526 | RCBTB1 | 55213 | RNAseq | 0.2427 | 0.2401 | |
| SRP193095 | RCBTB1 | 55213 | RNAseq | 0.3873 | 0.0000 | |
| SRP219564 | RCBTB1 | 55213 | RNAseq | 0.0802 | 0.7838 | |
| TCGA | RCBTB1 | 55213 | RNAseq | -0.1439 | 0.0694 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by RCBTB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RCBTB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCBTB1 | 55213 | 1 | 13 | 16 | |
| GSE20123 | RCBTB1 | 55213 | 1 | 12 | 17 | |
| GSE43470 | RCBTB1 | 55213 | 3 | 13 | 27 | |
| GSE46452 | RCBTB1 | 55213 | 0 | 32 | 27 | |
| GSE47630 | RCBTB1 | 55213 | 2 | 27 | 11 | |
| GSE54993 | RCBTB1 | 55213 | 12 | 2 | 56 | |
| GSE54994 | RCBTB1 | 55213 | 2 | 14 | 37 | |
| GSE60625 | RCBTB1 | 55213 | 0 | 3 | 8 | |
| GSE74703 | RCBTB1 | 55213 | 3 | 10 | 23 | |
| GSE74704 | RCBTB1 | 55213 | 0 | 9 | 11 | |
| TCGA | RCBTB1 | 55213 | 10 | 37 | 49 |
Total number of gains: 34; Total number of losses: 172; Total Number of normals: 282.
Somatic mutations of RCBTB1:
Generating mutation plots.
Highly correlated genes for RCBTB1:
Showing top 20/1253 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCBTB1 | SBNO1 | 0.852048 | 3 | 0 | 3 |
| RCBTB1 | CRTC2 | 0.80648 | 3 | 0 | 3 |
| RCBTB1 | ZNF473 | 0.786686 | 3 | 0 | 3 |
| RCBTB1 | KLHL21 | 0.776712 | 3 | 0 | 3 |
| RCBTB1 | CAMKK2 | 0.752868 | 3 | 0 | 3 |
| RCBTB1 | C20orf194 | 0.742551 | 4 | 0 | 4 |
| RCBTB1 | CCNT1 | 0.737798 | 3 | 0 | 3 |
| RCBTB1 | CLCN7 | 0.733785 | 3 | 0 | 3 |
| RCBTB1 | VPS36 | 0.731483 | 3 | 0 | 3 |
| RCBTB1 | CRKL | 0.729891 | 3 | 0 | 3 |
| RCBTB1 | CAPN12 | 0.725778 | 3 | 0 | 3 |
| RCBTB1 | BMI1 | 0.723777 | 3 | 0 | 3 |
| RCBTB1 | CNTNAP1 | 0.717216 | 3 | 0 | 3 |
| RCBTB1 | SGTB | 0.713569 | 5 | 0 | 5 |
| RCBTB1 | APOLD1 | 0.711722 | 3 | 0 | 3 |
| RCBTB1 | SLAIN1 | 0.710298 | 3 | 0 | 3 |
| RCBTB1 | TMC7 | 0.709047 | 3 | 0 | 3 |
| RCBTB1 | DDX60L | 0.707266 | 3 | 0 | 3 |
| RCBTB1 | MRPS9 | 0.706227 | 3 | 0 | 3 |
| RCBTB1 | LRRN4CL | 0.704668 | 3 | 0 | 3 |
For details and further investigation, click here
