| Full name: zinc finger protein 474 | Alias Symbol: 4933409D10Rik|FLJ32921 | ||
| Type: protein-coding gene | Cytoband: 5q23.2 | ||
| Entrez ID: 133923 | HGNC ID: HGNC:23245 | Ensembl Gene: ENSG00000164185 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF474:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF474 | 133923 | 1556907_at | -0.0727 | 0.8696 | |
| GSE26886 | ZNF474 | 133923 | 1556907_at | 0.2601 | 0.0253 | |
| GSE45670 | ZNF474 | 133923 | 1556907_at | 0.1849 | 0.1319 | |
| GSE53622 | ZNF474 | 133923 | 58583 | 0.1639 | 0.4708 | |
| GSE53624 | ZNF474 | 133923 | 58583 | 0.8742 | 0.0000 | |
| GSE63941 | ZNF474 | 133923 | 1556907_at | 0.1523 | 0.2233 | |
| GSE77861 | ZNF474 | 133923 | 1556907_at | -0.0543 | 0.6072 | |
| SRP133303 | ZNF474 | 133923 | RNAseq | 1.3658 | 0.0003 | |
| TCGA | ZNF474 | 133923 | RNAseq | 1.1123 | 0.0020 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZNF474 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF474:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF474 | 133923 | 1 | 13 | 16 | |
| GSE20123 | ZNF474 | 133923 | 1 | 13 | 16 | |
| GSE43470 | ZNF474 | 133923 | 3 | 8 | 32 | |
| GSE46452 | ZNF474 | 133923 | 0 | 27 | 32 | |
| GSE47630 | ZNF474 | 133923 | 0 | 21 | 19 | |
| GSE54993 | ZNF474 | 133923 | 9 | 1 | 60 | |
| GSE54994 | ZNF474 | 133923 | 2 | 14 | 37 | |
| GSE60625 | ZNF474 | 133923 | 0 | 0 | 11 | |
| GSE74703 | ZNF474 | 133923 | 2 | 6 | 28 | |
| GSE74704 | ZNF474 | 133923 | 1 | 7 | 12 | |
| TCGA | ZNF474 | 133923 | 3 | 40 | 53 |
Total number of gains: 22; Total number of losses: 150; Total Number of normals: 316.
Somatic mutations of ZNF474:
Generating mutation plots.
Highly correlated genes for ZNF474:
Showing top 20/25 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF474 | GLIS3-AS1 | 0.734702 | 3 | 0 | 3 |
| ZNF474 | FAM153A | 0.662562 | 3 | 0 | 3 |
| ZNF474 | OR12D2 | 0.644636 | 3 | 0 | 3 |
| ZNF474 | WWC2-AS2 | 0.628817 | 3 | 0 | 3 |
| ZNF474 | NTSR1 | 0.614297 | 3 | 0 | 3 |
| ZNF474 | AMER3 | 0.590988 | 4 | 0 | 3 |
| ZNF474 | RHOXF1 | 0.59069 | 3 | 0 | 3 |
| ZNF474 | FTO | 0.586044 | 3 | 0 | 3 |
| ZNF474 | C3orf22 | 0.567907 | 3 | 0 | 3 |
| ZNF474 | C1orf127 | 0.561199 | 3 | 0 | 3 |
| ZNF474 | B4GALNT4 | 0.560858 | 3 | 0 | 3 |
| ZNF474 | FOXL1 | 0.557042 | 3 | 0 | 3 |
| ZNF474 | MYLPF | 0.548531 | 3 | 0 | 3 |
| ZNF474 | COX6B2 | 0.537672 | 5 | 0 | 3 |
| ZNF474 | ITIH1 | 0.536333 | 3 | 0 | 3 |
| ZNF474 | PLAC8L1 | 0.53339 | 3 | 0 | 3 |
| ZNF474 | VSX1 | 0.530569 | 3 | 0 | 3 |
| ZNF474 | GRM7 | 0.529914 | 5 | 0 | 3 |
| ZNF474 | NAGS | 0.52831 | 5 | 0 | 3 |
| ZNF474 | KLF7 | 0.523835 | 5 | 0 | 3 |
For details and further investigation, click here
