| Full name: cytochrome c oxidase subunit 6B2 | Alias Symbol: COXVIB2|FLJ32865|CT59 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 125965 | HGNC ID: HGNC:24380 | Ensembl Gene: ENSG00000160471 | OMIM ID: 618127 |
| Drug and gene relationship at DGIdb | |||
Expression of COX6B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX6B2 | 125965 | 1553367_a_at | -0.0803 | 0.8397 | |
| GSE26886 | COX6B2 | 125965 | 1553367_a_at | 0.1270 | 0.4335 | |
| GSE45670 | COX6B2 | 125965 | 1553367_a_at | 0.4140 | 0.0081 | |
| GSE53622 | COX6B2 | 125965 | 35556 | 0.8155 | 0.0000 | |
| GSE53624 | COX6B2 | 125965 | 55899 | 1.1884 | 0.0000 | |
| GSE63941 | COX6B2 | 125965 | 1553367_a_at | 0.8053 | 0.0018 | |
| GSE77861 | COX6B2 | 125965 | 1553367_a_at | -0.0656 | 0.6406 | |
| GSE97050 | COX6B2 | 125965 | A_33_P3378284 | 0.8631 | 0.0620 | |
| SRP064894 | COX6B2 | 125965 | RNAseq | 2.3413 | 0.0000 | |
| SRP133303 | COX6B2 | 125965 | RNAseq | 0.8678 | 0.0108 | |
| SRP159526 | COX6B2 | 125965 | RNAseq | 0.8157 | 0.1364 | |
| SRP219564 | COX6B2 | 125965 | RNAseq | 1.4082 | 0.0299 | |
| TCGA | COX6B2 | 125965 | RNAseq | 2.2772 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by COX6B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COX6B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX6B2 | 125965 | 3 | 4 | 23 | |
| GSE20123 | COX6B2 | 125965 | 3 | 3 | 24 | |
| GSE43470 | COX6B2 | 125965 | 3 | 11 | 29 | |
| GSE46452 | COX6B2 | 125965 | 45 | 1 | 13 | |
| GSE47630 | COX6B2 | 125965 | 8 | 6 | 26 | |
| GSE54993 | COX6B2 | 125965 | 17 | 4 | 49 | |
| GSE54994 | COX6B2 | 125965 | 4 | 13 | 36 | |
| GSE60625 | COX6B2 | 125965 | 9 | 0 | 2 | |
| GSE74703 | COX6B2 | 125965 | 3 | 7 | 26 | |
| GSE74704 | COX6B2 | 125965 | 3 | 1 | 16 | |
| TCGA | COX6B2 | 125965 | 20 | 14 | 62 |
Total number of gains: 118; Total number of losses: 64; Total Number of normals: 306.
Somatic mutations of COX6B2:
Generating mutation plots.
Highly correlated genes for COX6B2:
Showing top 20/81 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX6B2 | SERPINB7 | 0.675584 | 3 | 0 | 3 |
| COX6B2 | CD58 | 0.66213 | 4 | 0 | 4 |
| COX6B2 | TGFA | 0.653258 | 3 | 0 | 3 |
| COX6B2 | IRAK2 | 0.649883 | 3 | 0 | 3 |
| COX6B2 | SFN | 0.642104 | 4 | 0 | 3 |
| COX6B2 | HPX | 0.637876 | 3 | 0 | 3 |
| COX6B2 | PKM | 0.63528 | 3 | 0 | 3 |
| COX6B2 | EXOC3L2 | 0.633726 | 3 | 0 | 3 |
| COX6B2 | PYCARD | 0.63145 | 3 | 0 | 3 |
| COX6B2 | KRTDAP | 0.629869 | 3 | 0 | 3 |
| COX6B2 | HYAL4 | 0.623434 | 4 | 0 | 3 |
| COX6B2 | LINC00221 | 0.621713 | 3 | 0 | 3 |
| COX6B2 | KLK5 | 0.614311 | 4 | 0 | 3 |
| COX6B2 | RCC2 | 0.610722 | 4 | 0 | 3 |
| COX6B2 | CDH3 | 0.598788 | 3 | 0 | 3 |
| COX6B2 | ADK | 0.596899 | 4 | 0 | 3 |
| COX6B2 | ADAMTS14 | 0.594066 | 4 | 0 | 4 |
| COX6B2 | RNF126 | 0.590461 | 4 | 0 | 3 |
| COX6B2 | SLC12A1 | 0.587547 | 4 | 0 | 3 |
| COX6B2 | MMP12 | 0.585204 | 4 | 0 | 3 |
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