| Full name: forkhead box L1 | Alias Symbol: FREAC7|FKH6 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 2300 | HGNC ID: HGNC:3817 | Ensembl Gene: ENSG00000176678 | OMIM ID: 603252 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXL1 | 2300 | 243409_at | 0.7158 | 0.2831 | |
| GSE20347 | FOXL1 | 2300 | 216572_at | 0.0529 | 0.4097 | |
| GSE23400 | FOXL1 | 2300 | 216572_at | -0.0387 | 0.2394 | |
| GSE26886 | FOXL1 | 2300 | 243409_at | 0.8992 | 0.0008 | |
| GSE29001 | FOXL1 | 2300 | 216572_at | -0.1154 | 0.2750 | |
| GSE38129 | FOXL1 | 2300 | 216572_at | 0.0025 | 0.9735 | |
| GSE45670 | FOXL1 | 2300 | 243409_at | 0.4309 | 0.1504 | |
| GSE53622 | FOXL1 | 2300 | 71844 | 1.2162 | 0.0000 | |
| GSE53624 | FOXL1 | 2300 | 71844 | 1.8065 | 0.0000 | |
| GSE63941 | FOXL1 | 2300 | 243409_at | -2.1333 | 0.0049 | |
| GSE77861 | FOXL1 | 2300 | 243409_at | 0.2023 | 0.2038 | |
| GSE97050 | FOXL1 | 2300 | A_33_P3355503 | 0.1059 | 0.5745 | |
| SRP133303 | FOXL1 | 2300 | RNAseq | 0.8640 | 0.0198 | |
| SRP159526 | FOXL1 | 2300 | RNAseq | 2.5901 | 0.0005 | |
| SRP219564 | FOXL1 | 2300 | RNAseq | 2.2473 | 0.0000 | |
| TCGA | FOXL1 | 2300 | RNAseq | 0.7440 | 0.0067 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by FOXL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXL1 | 2300 | 5 | 2 | 23 | |
| GSE20123 | FOXL1 | 2300 | 5 | 2 | 23 | |
| GSE43470 | FOXL1 | 2300 | 2 | 12 | 29 | |
| GSE46452 | FOXL1 | 2300 | 38 | 1 | 20 | |
| GSE47630 | FOXL1 | 2300 | 11 | 9 | 20 | |
| GSE54993 | FOXL1 | 2300 | 3 | 4 | 63 | |
| GSE54994 | FOXL1 | 2300 | 9 | 11 | 33 | |
| GSE60625 | FOXL1 | 2300 | 4 | 0 | 7 | |
| GSE74703 | FOXL1 | 2300 | 1 | 9 | 26 | |
| GSE74704 | FOXL1 | 2300 | 3 | 2 | 15 | |
| TCGA | FOXL1 | 2300 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 67; Total Number of normals: 313.
Somatic mutations of FOXL1:
Generating mutation plots.
Highly correlated genes for FOXL1:
Showing top 20/237 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXL1 | DOCK4 | 0.752767 | 3 | 0 | 3 |
| FOXL1 | LPP-AS2 | 0.702211 | 3 | 0 | 3 |
| FOXL1 | DNER | 0.685146 | 4 | 0 | 4 |
| FOXL1 | PHF21A | 0.684188 | 3 | 0 | 3 |
| FOXL1 | LRWD1 | 0.667857 | 3 | 0 | 3 |
| FOXL1 | NPW | 0.663826 | 4 | 0 | 3 |
| FOXL1 | SNAI2 | 0.653789 | 6 | 0 | 6 |
| FOXL1 | EMC8 | 0.652372 | 3 | 0 | 3 |
| FOXL1 | OLIG3 | 0.650015 | 4 | 0 | 3 |
| FOXL1 | DCBLD1 | 0.644925 | 6 | 0 | 5 |
| FOXL1 | SPRR2G | 0.644764 | 4 | 0 | 3 |
| FOXL1 | CCDC81 | 0.644583 | 4 | 0 | 4 |
| FOXL1 | INHBA | 0.644031 | 7 | 0 | 7 |
| FOXL1 | GALNS | 0.642725 | 6 | 0 | 6 |
| FOXL1 | CCNA1 | 0.642666 | 6 | 0 | 5 |
| FOXL1 | THY1 | 0.641236 | 5 | 0 | 5 |
| FOXL1 | LAMC2 | 0.641088 | 6 | 0 | 6 |
| FOXL1 | TNFRSF18 | 0.633179 | 4 | 0 | 3 |
| FOXL1 | AP5S1 | 0.631813 | 4 | 0 | 4 |
| FOXL1 | FAM216A | 0.631487 | 4 | 0 | 3 |
For details and further investigation, click here
