| Full name: inter-alpha-trypsin inhibitor heavy chain 1 | Alias Symbol: H1P|IATIH|ITIH | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 3697 | HGNC ID: HGNC:6166 | Ensembl Gene: ENSG00000055957 | OMIM ID: 147270 |
| Drug and gene relationship at DGIdb | |||
Expression of ITIH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ITIH1 | 3697 | 210888_s_at | -0.0942 | 0.7718 | |
| GSE20347 | ITIH1 | 3697 | 210888_s_at | -0.0671 | 0.3515 | |
| GSE23400 | ITIH1 | 3697 | 210888_s_at | -0.0684 | 0.0171 | |
| GSE26886 | ITIH1 | 3697 | 210888_s_at | 0.1614 | 0.1629 | |
| GSE29001 | ITIH1 | 3697 | 210888_s_at | 0.0435 | 0.7709 | |
| GSE38129 | ITIH1 | 3697 | 210888_s_at | -0.0665 | 0.2736 | |
| GSE45670 | ITIH1 | 3697 | 210888_s_at | -0.0625 | 0.4656 | |
| GSE53622 | ITIH1 | 3697 | 45322 | -0.3276 | 0.0014 | |
| GSE53624 | ITIH1 | 3697 | 40984 | -1.0802 | 0.0000 | |
| GSE63941 | ITIH1 | 3697 | 210888_s_at | -0.0196 | 0.9148 | |
| GSE77861 | ITIH1 | 3697 | 210888_s_at | -0.1326 | 0.3408 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ITIH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ITIH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ITIH1 | 3697 | 0 | 18 | 12 | |
| GSE20123 | ITIH1 | 3697 | 0 | 19 | 11 | |
| GSE43470 | ITIH1 | 3697 | 0 | 18 | 25 | |
| GSE46452 | ITIH1 | 3697 | 2 | 17 | 40 | |
| GSE47630 | ITIH1 | 3697 | 1 | 24 | 15 | |
| GSE54993 | ITIH1 | 3697 | 6 | 2 | 62 | |
| GSE54994 | ITIH1 | 3697 | 0 | 33 | 20 | |
| GSE60625 | ITIH1 | 3697 | 5 | 0 | 6 | |
| GSE74703 | ITIH1 | 3697 | 0 | 14 | 22 | |
| GSE74704 | ITIH1 | 3697 | 0 | 12 | 8 | |
| TCGA | ITIH1 | 3697 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 235; Total Number of normals: 239.
Somatic mutations of ITIH1:
Generating mutation plots.
Highly correlated genes for ITIH1:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ITIH1 | CXCR5 | 0.710596 | 3 | 0 | 3 |
| ITIH1 | AFP | 0.699598 | 3 | 0 | 3 |
| ITIH1 | CKM | 0.681825 | 3 | 0 | 3 |
| ITIH1 | KCNQ2 | 0.678993 | 6 | 0 | 5 |
| ITIH1 | IRS4 | 0.673209 | 5 | 0 | 5 |
| ITIH1 | PCBP3 | 0.662839 | 4 | 0 | 4 |
| ITIH1 | IQCC | 0.66189 | 3 | 0 | 3 |
| ITIH1 | MIP | 0.661794 | 3 | 0 | 3 |
| ITIH1 | ZSCAN2 | 0.661169 | 5 | 0 | 5 |
| ITIH1 | KHDC3L | 0.660976 | 3 | 0 | 3 |
| ITIH1 | ARHGAP30 | 0.655377 | 3 | 0 | 3 |
| ITIH1 | YTHDF3-AS1 | 0.653563 | 3 | 0 | 3 |
| ITIH1 | FMN2 | 0.652858 | 3 | 0 | 3 |
| ITIH1 | ZP2 | 0.65224 | 4 | 0 | 3 |
| ITIH1 | ANKFN1 | 0.652043 | 3 | 0 | 3 |
| ITIH1 | HTR1A | 0.646585 | 4 | 0 | 4 |
| ITIH1 | SGCD | 0.645825 | 4 | 0 | 4 |
| ITIH1 | MTAP | 0.644989 | 5 | 0 | 4 |
| ITIH1 | VGF | 0.644215 | 4 | 0 | 3 |
| ITIH1 | CDH4 | 0.643659 | 4 | 0 | 3 |
For details and further investigation, click here
