| Full name: APC membrane recruitment protein 3 | Alias Symbol: FLJ38377 | ||
| Type: protein-coding gene | Cytoband: 2q21.1 | ||
| Entrez ID: 205147 | HGNC ID: HGNC:26771 | Ensembl Gene: ENSG00000178171 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of AMER3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMER3 | 205147 | 244709_at | -0.0198 | 0.9645 | |
| GSE26886 | AMER3 | 205147 | 244709_at | 0.3162 | 0.0235 | |
| GSE45670 | AMER3 | 205147 | 236638_at | 0.0080 | 0.9389 | |
| GSE53622 | AMER3 | 205147 | 15401 | 0.2836 | 0.0709 | |
| GSE53624 | AMER3 | 205147 | 15401 | -0.0055 | 0.9643 | |
| GSE63941 | AMER3 | 205147 | 244709_at | -0.0056 | 0.9814 | |
| GSE77861 | AMER3 | 205147 | 244709_at | -0.2333 | 0.0317 | |
| SRP133303 | AMER3 | 205147 | RNAseq | -0.1284 | 0.4358 | |
| SRP193095 | AMER3 | 205147 | RNAseq | -0.2385 | 0.2103 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AMER3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AMER3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMER3 | 205147 | 5 | 3 | 22 | |
| GSE20123 | AMER3 | 205147 | 5 | 3 | 22 | |
| GSE43470 | AMER3 | 205147 | 2 | 2 | 39 | |
| GSE46452 | AMER3 | 205147 | 1 | 3 | 55 | |
| GSE47630 | AMER3 | 205147 | 5 | 0 | 35 | |
| GSE54993 | AMER3 | 205147 | 0 | 6 | 64 | |
| GSE54994 | AMER3 | 205147 | 10 | 0 | 43 | |
| GSE60625 | AMER3 | 205147 | 0 | 3 | 8 | |
| GSE74703 | AMER3 | 205147 | 2 | 1 | 33 | |
| GSE74704 | AMER3 | 205147 | 3 | 1 | 16 | |
| TCGA | AMER3 | 205147 | 22 | 9 | 65 |
Total number of gains: 55; Total number of losses: 31; Total Number of normals: 402.
Somatic mutations of AMER3:
Generating mutation plots.
Highly correlated genes for AMER3:
Showing top 20/135 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMER3 | CCIN | 0.719854 | 3 | 0 | 3 |
| AMER3 | GATA4 | 0.712612 | 3 | 0 | 3 |
| AMER3 | GJA3 | 0.704666 | 3 | 0 | 3 |
| AMER3 | RETN | 0.704008 | 3 | 0 | 3 |
| AMER3 | GFER | 0.69565 | 3 | 0 | 3 |
| AMER3 | NRG1 | 0.690339 | 3 | 0 | 3 |
| AMER3 | LIM2 | 0.686214 | 3 | 0 | 3 |
| AMER3 | ARMC5 | 0.685126 | 3 | 0 | 3 |
| AMER3 | NOXO1 | 0.682848 | 3 | 0 | 3 |
| AMER3 | PPP1R3F | 0.677508 | 3 | 0 | 3 |
| AMER3 | KCNF1 | 0.674778 | 3 | 0 | 3 |
| AMER3 | CLDN9 | 0.672537 | 5 | 0 | 4 |
| AMER3 | SMIM6 | 0.666662 | 3 | 0 | 3 |
| AMER3 | CSF3 | 0.664998 | 3 | 0 | 3 |
| AMER3 | PAGE1 | 0.661754 | 3 | 0 | 3 |
| AMER3 | FRMD7 | 0.652022 | 3 | 0 | 3 |
| AMER3 | GAD1 | 0.650545 | 3 | 0 | 3 |
| AMER3 | INS | 0.639778 | 4 | 0 | 3 |
| AMER3 | KLK14 | 0.638151 | 3 | 0 | 3 |
| AMER3 | LINC00644 | 0.634781 | 3 | 0 | 3 |
For details and further investigation, click here
