| Full name: Kruppel like factor 7 | Alias Symbol: UKLF | ||
| Type: protein-coding gene | Cytoband: 2q33.3 | ||
| Entrez ID: 8609 | HGNC ID: HGNC:6350 | Ensembl Gene: ENSG00000118263 | OMIM ID: 604865 |
| Drug and gene relationship at DGIdb | |||
Expression of KLF7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF7 | 8609 | 204334_at | 0.2364 | 0.8147 | |
| GSE20347 | KLF7 | 8609 | 204334_at | 0.8214 | 0.0000 | |
| GSE23400 | KLF7 | 8609 | 204334_at | 0.3680 | 0.0000 | |
| GSE26886 | KLF7 | 8609 | 204334_at | 2.0972 | 0.0000 | |
| GSE29001 | KLF7 | 8609 | 204334_at | 0.9553 | 0.0011 | |
| GSE38129 | KLF7 | 8609 | 204334_at | 0.5080 | 0.0310 | |
| GSE45670 | KLF7 | 8609 | 204334_at | 0.3305 | 0.3969 | |
| GSE53622 | KLF7 | 8609 | 137758 | 0.9982 | 0.0000 | |
| GSE53624 | KLF7 | 8609 | 137758 | 1.1503 | 0.0000 | |
| GSE63941 | KLF7 | 8609 | 204334_at | -1.8107 | 0.0120 | |
| GSE77861 | KLF7 | 8609 | 204334_at | 1.3123 | 0.0055 | |
| GSE97050 | KLF7 | 8609 | A_23_P67980 | 0.1611 | 0.6395 | |
| SRP007169 | KLF7 | 8609 | RNAseq | 1.8638 | 0.0000 | |
| SRP008496 | KLF7 | 8609 | RNAseq | 2.2895 | 0.0000 | |
| SRP064894 | KLF7 | 8609 | RNAseq | 1.1392 | 0.0000 | |
| SRP133303 | KLF7 | 8609 | RNAseq | 1.1751 | 0.0002 | |
| SRP159526 | KLF7 | 8609 | RNAseq | 0.4001 | 0.2152 | |
| SRP193095 | KLF7 | 8609 | RNAseq | 2.0175 | 0.0000 | |
| SRP219564 | KLF7 | 8609 | RNAseq | 0.4606 | 0.2556 | |
| TCGA | KLF7 | 8609 | RNAseq | 0.1582 | 0.2333 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by KLF7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLF7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLF7 | 8609 | 3 | 6 | 21 | |
| GSE20123 | KLF7 | 8609 | 3 | 6 | 21 | |
| GSE43470 | KLF7 | 8609 | 2 | 4 | 37 | |
| GSE46452 | KLF7 | 8609 | 1 | 4 | 54 | |
| GSE47630 | KLF7 | 8609 | 4 | 5 | 31 | |
| GSE54993 | KLF7 | 8609 | 0 | 3 | 67 | |
| GSE54994 | KLF7 | 8609 | 8 | 9 | 36 | |
| GSE60625 | KLF7 | 8609 | 0 | 3 | 8 | |
| GSE74703 | KLF7 | 8609 | 2 | 3 | 31 | |
| GSE74704 | KLF7 | 8609 | 2 | 2 | 16 | |
| TCGA | KLF7 | 8609 | 14 | 22 | 60 |
Total number of gains: 39; Total number of losses: 67; Total Number of normals: 382.
Somatic mutations of KLF7:
Generating mutation plots.
Highly correlated genes for KLF7:
Showing top 20/1517 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF7 | C11orf96 | 0.84347 | 3 | 0 | 3 |
| KLF7 | PCDH18 | 0.83043 | 3 | 0 | 3 |
| KLF7 | TRIM47 | 0.824882 | 3 | 0 | 3 |
| KLF7 | TIGD1 | 0.794528 | 3 | 0 | 3 |
| KLF7 | BBS9 | 0.77934 | 3 | 0 | 3 |
| KLF7 | WDR81 | 0.767689 | 3 | 0 | 3 |
| KLF7 | SNTA1 | 0.767592 | 3 | 0 | 3 |
| KLF7 | INHBA | 0.766225 | 11 | 0 | 11 |
| KLF7 | RILPL1 | 0.764599 | 4 | 0 | 4 |
| KLF7 | FBLIM1 | 0.763664 | 7 | 0 | 7 |
| KLF7 | TMX3 | 0.76179 | 3 | 0 | 3 |
| KLF7 | GNG10 | 0.754623 | 3 | 0 | 3 |
| KLF7 | LRRC8C | 0.753564 | 3 | 0 | 3 |
| KLF7 | CD93 | 0.751133 | 3 | 0 | 3 |
| KLF7 | FGF7 | 0.75008 | 3 | 0 | 3 |
| KLF7 | ZNF417 | 0.743187 | 3 | 0 | 3 |
| KLF7 | CLIP3 | 0.741331 | 4 | 0 | 4 |
| KLF7 | CTF1 | 0.738964 | 3 | 0 | 3 |
| KLF7 | MNT | 0.733417 | 3 | 0 | 3 |
| KLF7 | ALKBH6 | 0.73215 | 4 | 0 | 3 |
For details and further investigation, click here
