| Full name: zinc finger protein 589 | Alias Symbol: SZF1 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 51385 | HGNC ID: HGNC:16747 | Ensembl Gene: ENSG00000164048 | OMIM ID: 616702 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF589:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF589 | 51385 | 219968_at | -0.3577 | 0.3250 | |
| GSE20347 | ZNF589 | 51385 | 219968_at | -0.2726 | 0.0152 | |
| GSE23400 | ZNF589 | 51385 | 219968_at | -0.3585 | 0.0000 | |
| GSE26886 | ZNF589 | 51385 | 219968_at | -0.8275 | 0.0001 | |
| GSE29001 | ZNF589 | 51385 | 219968_at | -0.3304 | 0.1599 | |
| GSE38129 | ZNF589 | 51385 | 219968_at | -0.3665 | 0.0003 | |
| GSE45670 | ZNF589 | 51385 | 219968_at | 0.1214 | 0.3362 | |
| GSE53622 | ZNF589 | 51385 | 88918 | 0.1548 | 0.0219 | |
| GSE53624 | ZNF589 | 51385 | 88918 | 0.2787 | 0.0009 | |
| GSE63941 | ZNF589 | 51385 | 219968_at | 0.3958 | 0.3260 | |
| GSE77861 | ZNF589 | 51385 | 219968_at | -0.1341 | 0.3559 | |
| GSE97050 | ZNF589 | 51385 | A_33_P3350306 | -0.1015 | 0.6202 | |
| SRP007169 | ZNF589 | 51385 | RNAseq | 0.8700 | 0.0531 | |
| SRP008496 | ZNF589 | 51385 | RNAseq | 0.9964 | 0.0113 | |
| SRP064894 | ZNF589 | 51385 | RNAseq | -0.1658 | 0.4211 | |
| SRP133303 | ZNF589 | 51385 | RNAseq | -0.0146 | 0.9645 | |
| SRP159526 | ZNF589 | 51385 | RNAseq | 0.3318 | 0.4361 | |
| SRP193095 | ZNF589 | 51385 | RNAseq | -0.0384 | 0.8440 | |
| SRP219564 | ZNF589 | 51385 | RNAseq | -0.7949 | 0.0187 | |
| TCGA | ZNF589 | 51385 | RNAseq | -0.1759 | 0.0350 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF589 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF589:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF589 | 51385 | 0 | 18 | 12 | |
| GSE20123 | ZNF589 | 51385 | 0 | 19 | 11 | |
| GSE43470 | ZNF589 | 51385 | 0 | 19 | 24 | |
| GSE46452 | ZNF589 | 51385 | 2 | 17 | 40 | |
| GSE47630 | ZNF589 | 51385 | 1 | 24 | 15 | |
| GSE54993 | ZNF589 | 51385 | 6 | 2 | 62 | |
| GSE54994 | ZNF589 | 51385 | 0 | 36 | 17 | |
| GSE60625 | ZNF589 | 51385 | 5 | 0 | 6 | |
| GSE74703 | ZNF589 | 51385 | 0 | 15 | 21 | |
| GSE74704 | ZNF589 | 51385 | 0 | 12 | 8 | |
| TCGA | ZNF589 | 51385 | 0 | 77 | 19 |
Total number of gains: 14; Total number of losses: 239; Total Number of normals: 235.
Somatic mutations of ZNF589:
Generating mutation plots.
Highly correlated genes for ZNF589:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF589 | LINC00271 | 0.690131 | 3 | 0 | 3 |
| ZNF589 | TMEM235 | 0.684843 | 3 | 0 | 3 |
| ZNF589 | CECR9 | 0.67609 | 3 | 0 | 3 |
| ZNF589 | PSG6 | 0.67135 | 4 | 0 | 4 |
| ZNF589 | RNF180 | 0.671324 | 4 | 0 | 4 |
| ZNF589 | SPATA32 | 0.661159 | 3 | 0 | 3 |
| ZNF589 | ZNF527 | 0.654724 | 3 | 0 | 3 |
| ZNF589 | C9orf153 | 0.654302 | 3 | 0 | 3 |
| ZNF589 | HCG18 | 0.653343 | 4 | 0 | 3 |
| ZNF589 | RP1L1 | 0.652759 | 3 | 0 | 3 |
| ZNF589 | PLA2G12B | 0.652565 | 3 | 0 | 3 |
| ZNF589 | KLF17 | 0.648874 | 3 | 0 | 3 |
| ZNF589 | FAM219B | 0.648653 | 3 | 0 | 3 |
| ZNF589 | NUTM1 | 0.64848 | 4 | 0 | 4 |
| ZNF589 | MRGPRG | 0.646368 | 3 | 0 | 3 |
| ZNF589 | TTTY11 | 0.644873 | 4 | 0 | 4 |
| ZNF589 | C2CD4D | 0.640137 | 3 | 0 | 3 |
| ZNF589 | LGALS13 | 0.637676 | 3 | 0 | 3 |
| ZNF589 | SLC30A2 | 0.636254 | 4 | 0 | 3 |
| ZNF589 | LINC00423 | 0.636246 | 3 | 0 | 3 |
For details and further investigation, click here
