| Full name: family with sequence similarity 219 member B | Alias Symbol: FLJ00005 | ||
| Type: protein-coding gene | Cytoband: 15q24.1-q24.2 | ||
| Entrez ID: 57184 | HGNC ID: HGNC:24695 | Ensembl Gene: ENSG00000178761 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM219B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM219B | 57184 | 224804_s_at | -0.8314 | 0.0271 | |
| GSE26886 | FAM219B | 57184 | 224804_s_at | -1.0212 | 0.0002 | |
| GSE45670 | FAM219B | 57184 | 224804_s_at | -0.6867 | 0.0002 | |
| GSE63941 | FAM219B | 57184 | 224804_s_at | -1.1728 | 0.0039 | |
| GSE77861 | FAM219B | 57184 | 224804_s_at | -0.6030 | 0.0164 | |
| SRP007169 | FAM219B | 57184 | RNAseq | -2.3596 | 0.0000 | |
| SRP008496 | FAM219B | 57184 | RNAseq | -2.0413 | 0.0000 | |
| SRP064894 | FAM219B | 57184 | RNAseq | -1.1754 | 0.0000 | |
| SRP133303 | FAM219B | 57184 | RNAseq | -1.0449 | 0.0000 | |
| SRP159526 | FAM219B | 57184 | RNAseq | -1.1823 | 0.0000 | |
| SRP193095 | FAM219B | 57184 | RNAseq | -1.1013 | 0.0000 | |
| SRP219564 | FAM219B | 57184 | RNAseq | -1.0992 | 0.0017 |
Upregulated datasets: 0; Downregulated datasets: 9.
Copy number change of FAM219B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM219B | 57184 | 8 | 1 | 21 | |
| GSE20123 | FAM219B | 57184 | 8 | 1 | 21 | |
| GSE43470 | FAM219B | 57184 | 4 | 6 | 33 | |
| GSE46452 | FAM219B | 57184 | 3 | 7 | 49 | |
| GSE47630 | FAM219B | 57184 | 8 | 10 | 22 | |
| GSE54993 | FAM219B | 57184 | 5 | 6 | 59 | |
| GSE54994 | FAM219B | 57184 | 5 | 7 | 41 | |
| GSE60625 | FAM219B | 57184 | 4 | 0 | 7 | |
| GSE74703 | FAM219B | 57184 | 4 | 3 | 29 | |
| GSE74704 | FAM219B | 57184 | 4 | 1 | 15 | |
| TCGA | FAM219B | 57184 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 57; Total Number of normals: 364.
Somatic mutations of FAM219B:
Generating mutation plots.
Highly correlated genes for FAM219B:
Showing top 20/836 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM219B | SORT1 | 0.807587 | 4 | 0 | 4 |
| FAM219B | SH3BGRL2 | 0.807083 | 4 | 0 | 4 |
| FAM219B | MGST2 | 0.805609 | 4 | 0 | 4 |
| FAM219B | ECHDC2 | 0.798189 | 4 | 0 | 4 |
| FAM219B | ZNF662 | 0.793719 | 4 | 0 | 4 |
| FAM219B | PAQR8 | 0.775717 | 4 | 0 | 4 |
| FAM219B | FAM189A2 | 0.774097 | 4 | 0 | 4 |
| FAM219B | AGFG2 | 0.772077 | 4 | 0 | 4 |
| FAM219B | CAST | 0.770994 | 4 | 0 | 4 |
| FAM219B | GALNT12 | 0.770323 | 4 | 0 | 4 |
| FAM219B | CCNDBP1 | 0.769675 | 3 | 0 | 3 |
| FAM219B | TFAP2B | 0.768955 | 4 | 0 | 4 |
| FAM219B | ARHGEF10L | 0.766861 | 4 | 0 | 4 |
| FAM219B | TRIOBP | 0.765016 | 3 | 0 | 3 |
| FAM219B | HLF | 0.76376 | 3 | 0 | 3 |
| FAM219B | SECISBP2L | 0.762338 | 5 | 0 | 5 |
| FAM219B | CAB39L | 0.760182 | 4 | 0 | 4 |
| FAM219B | RBPMS | 0.753758 | 4 | 0 | 3 |
| FAM219B | ASAP3 | 0.753737 | 3 | 0 | 3 |
| FAM219B | CTTNBP2 | 0.753422 | 5 | 0 | 5 |
For details and further investigation, click here
