RP1L1

 

Full name: RP1 like 1 Alias Symbol: DCDC4B
Type: protein-coding gene Cytoband: 8p23.1
Entrez ID: 94137 HGNC ID: HGNC:15946 Ensembl Gene: ENSG00000183638 OMIM ID: 608581
Drug and gene relationship at DGIdb

 

Expression of RP1L1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RP1L1 94137 1555245_s_at -0.1832 0.4965
GSE26886 RP1L1 94137 1555245_s_at -0.0570 0.6759
GSE45670 RP1L1 94137 1555245_s_at 0.2165 0.0306
GSE53622 RP1L1 94137 96404 -0.1843 0.0238
GSE53624 RP1L1 94137 96404 -0.3567 0.0000
GSE63941 RP1L1 94137 1555245_s_at 0.2417 0.1178
GSE77861 RP1L1 94137 1555245_s_at -0.1143 0.2362
GSE97050 RP1L1 94137 A_23_P309396 -0.2343 0.5883
SRP133303 RP1L1 94137 RNAseq -0.7502 0.0893
TCGA RP1L1 94137 RNAseq 0.6860 0.0195

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RP1L1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RP1L1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RP1L1 94137 4 11 15
GSE20123 RP1L1 94137 4 11 15
GSE43470 RP1L1 94137 4 9 30
GSE46452 RP1L1 94137 12 14 33
GSE47630 RP1L1 94137 10 7 23
GSE54993 RP1L1 94137 3 14 53
GSE54994 RP1L1 94137 9 19 25
GSE60625 RP1L1 94137 3 0 8
GSE74703 RP1L1 94137 4 7 25
GSE74704 RP1L1 94137 3 7 10
TCGA RP1L1 94137 13 40 43

Total number of gains: 69; Total number of losses: 139; Total Number of normals: 280.  


 

Somatic mutations of RP1L1:

 

Generating mutation plots.

 

Highly correlated genes for RP1L1:

 

Showing top 20/85 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RP1L1DEFB1210.796705303
RP1L1LACRT0.7334303
RP1L1DIO20.713579303
RP1L1GPR780.710862303
RP1L1MUC20.689631303
RP1L1RTEL10.683923303
RP1L1SLC37A10.681406303
RP1L1BCL2L150.673253303
RP1L1GLYATL10.672842303
RP1L1OR4D10.671601303
RP1L1LDHC0.66828303
RP1L1ADAMTSL40.665361303
RP1L1AIRE0.662544303
RP1L1KLF170.662538403
RP1L1DDX19B0.661808303
RP1L1ZNF5890.652759303
RP1L1GFRA20.650916403
RP1L1SYNGAP10.649404303
RP1L1ZGLP10.64502403
RP1L1ANKRD330.64119404

For details and further investigation, click here