| Full name: zinc finger protein 654 | Alias Symbol: FLJ10997|FLJ21142 | ||
| Type: protein-coding gene | Cytoband: 3p11.1 | ||
| Entrez ID: 55279 | HGNC ID: HGNC:25612 | Ensembl Gene: ENSG00000175105 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF654:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF654 | 55279 | 1556744_a_at | 0.1719 | 0.8536 | |
| GSE20347 | ZNF654 | 55279 | 219239_s_at | -0.5228 | 0.0004 | |
| GSE23400 | ZNF654 | 55279 | 219239_s_at | -0.1493 | 0.0082 | |
| GSE26886 | ZNF654 | 55279 | 241348_at | -1.4490 | 0.0000 | |
| GSE29001 | ZNF654 | 55279 | 219239_s_at | -0.6068 | 0.1264 | |
| GSE38129 | ZNF654 | 55279 | 219239_s_at | -0.5439 | 0.0041 | |
| GSE45670 | ZNF654 | 55279 | 241348_at | -0.2187 | 0.2782 | |
| GSE53622 | ZNF654 | 55279 | 21977 | -0.8508 | 0.0000 | |
| GSE53624 | ZNF654 | 55279 | 21977 | -0.9318 | 0.0000 | |
| GSE63941 | ZNF654 | 55279 | 241348_at | -1.1614 | 0.0539 | |
| GSE77861 | ZNF654 | 55279 | 241348_at | -0.7149 | 0.0133 | |
| GSE97050 | ZNF654 | 55279 | A_33_P3268124 | -0.4287 | 0.1417 | |
| SRP007169 | ZNF654 | 55279 | RNAseq | -1.3172 | 0.0000 | |
| SRP008496 | ZNF654 | 55279 | RNAseq | -1.2952 | 0.0000 | |
| SRP064894 | ZNF654 | 55279 | RNAseq | -0.8631 | 0.0053 | |
| SRP133303 | ZNF654 | 55279 | RNAseq | 0.1163 | 0.7130 | |
| SRP159526 | ZNF654 | 55279 | RNAseq | -0.6971 | 0.1082 | |
| SRP193095 | ZNF654 | 55279 | RNAseq | -0.9626 | 0.0000 | |
| SRP219564 | ZNF654 | 55279 | RNAseq | -1.0381 | 0.0233 | |
| TCGA | ZNF654 | 55279 | RNAseq | -0.2364 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ZNF654 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF654:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF654 | 55279 | 3 | 15 | 12 | |
| GSE20123 | ZNF654 | 55279 | 3 | 16 | 11 | |
| GSE43470 | ZNF654 | 55279 | 4 | 19 | 20 | |
| GSE46452 | ZNF654 | 55279 | 3 | 16 | 40 | |
| GSE47630 | ZNF654 | 55279 | 4 | 18 | 18 | |
| GSE54993 | ZNF654 | 55279 | 4 | 3 | 63 | |
| GSE54994 | ZNF654 | 55279 | 3 | 27 | 23 | |
| GSE60625 | ZNF654 | 55279 | 0 | 6 | 5 | |
| GSE74703 | ZNF654 | 55279 | 4 | 17 | 15 | |
| GSE74704 | ZNF654 | 55279 | 2 | 11 | 7 | |
| TCGA | ZNF654 | 55279 | 3 | 70 | 23 |
Total number of gains: 33; Total number of losses: 218; Total Number of normals: 237.
Somatic mutations of ZNF654:
Generating mutation plots.
Highly correlated genes for ZNF654:
Showing top 20/1128 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF654 | HDHD2 | 0.805257 | 4 | 0 | 4 |
| ZNF654 | TBRG1 | 0.805118 | 3 | 0 | 3 |
| ZNF654 | PFKFB2 | 0.793608 | 3 | 0 | 3 |
| ZNF654 | ZNF717 | 0.764335 | 4 | 0 | 3 |
| ZNF654 | CCNYL1 | 0.747319 | 4 | 0 | 4 |
| ZNF654 | RBM8A | 0.733357 | 5 | 0 | 5 |
| ZNF654 | C5orf51 | 0.733265 | 3 | 0 | 3 |
| ZNF654 | SLC22A15 | 0.729154 | 3 | 0 | 3 |
| ZNF654 | MAP3K1 | 0.728974 | 7 | 0 | 6 |
| ZNF654 | C6orf62 | 0.727411 | 5 | 0 | 4 |
| ZNF654 | BTBD7 | 0.726283 | 4 | 0 | 3 |
| ZNF654 | NFIA | 0.725083 | 5 | 0 | 4 |
| ZNF654 | EXOC8 | 0.725023 | 4 | 0 | 4 |
| ZNF654 | CA13 | 0.720421 | 3 | 0 | 3 |
| ZNF654 | C3orf38 | 0.720007 | 9 | 0 | 9 |
| ZNF654 | FAM122A | 0.716873 | 3 | 0 | 3 |
| ZNF654 | COMMD9 | 0.714612 | 4 | 0 | 3 |
| ZNF654 | UBE2V2 | 0.713983 | 4 | 0 | 3 |
| ZNF654 | BAZ2B | 0.710424 | 8 | 0 | 8 |
| ZNF654 | TRIM6 | 0.708769 | 6 | 0 | 6 |
For details and further investigation, click here
