| Full name: zinc finger protein 717 | Alias Symbol: X17 | ||
| Type: protein-coding gene | Cytoband: 3p12.3 | ||
| Entrez ID: 100131827 | HGNC ID: HGNC:29448 | Ensembl Gene: ENSG00000227124 | OMIM ID: 618405 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF717:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF717 | 100131827 | 229986_at | -0.3923 | 0.5150 | |
| GSE20347 | ZNF717 | 100131827 | 221370_at | -0.1144 | 0.0546 | |
| GSE23400 | ZNF717 | 100131827 | 221370_at | -0.2307 | 0.0000 | |
| GSE26886 | ZNF717 | 100131827 | 229986_at | -0.9970 | 0.0000 | |
| GSE29001 | ZNF717 | 100131827 | 221370_at | -0.2286 | 0.1440 | |
| GSE38129 | ZNF717 | 100131827 | 221370_at | -0.1327 | 0.0153 | |
| GSE45670 | ZNF717 | 100131827 | 229986_at | -0.5157 | 0.0765 | |
| GSE53622 | ZNF717 | 100131827 | 53812 | -1.0454 | 0.0000 | |
| GSE53624 | ZNF717 | 100131827 | 53812 | -0.9625 | 0.0000 | |
| GSE63941 | ZNF717 | 100131827 | 229986_at | -1.3379 | 0.0729 | |
| GSE77861 | ZNF717 | 100131827 | 229986_at | -0.6630 | 0.0084 | |
| GSE97050 | ZNF717 | 100131827 | A_23_P6980 | -0.8140 | 0.0888 | |
| SRP007169 | ZNF717 | 100131827 | RNAseq | -0.5602 | 0.3675 | |
| SRP064894 | ZNF717 | 100131827 | RNAseq | -0.7161 | 0.0051 | |
| SRP133303 | ZNF717 | 100131827 | RNAseq | -0.8191 | 0.0122 | |
| SRP159526 | ZNF717 | 100131827 | RNAseq | -1.1826 | 0.0034 | |
| SRP193095 | ZNF717 | 100131827 | RNAseq | -0.6846 | 0.0004 | |
| SRP219564 | ZNF717 | 100131827 | RNAseq | -0.7766 | 0.2006 | |
| TCGA | ZNF717 | 100131827 | RNAseq | -0.9477 | 0.0031 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZNF717 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF717:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF717 | 100131827 | 2 | 18 | 10 | |
| GSE20123 | ZNF717 | 100131827 | 2 | 18 | 10 | |
| GSE43470 | ZNF717 | 100131827 | 0 | 20 | 23 | |
| GSE46452 | ZNF717 | 100131827 | 2 | 17 | 40 | |
| GSE47630 | ZNF717 | 100131827 | 1 | 24 | 15 | |
| GSE54993 | ZNF717 | 100131827 | 4 | 3 | 63 | |
| GSE54994 | ZNF717 | 100131827 | 1 | 31 | 21 | |
| GSE60625 | ZNF717 | 100131827 | 3 | 1 | 7 | |
| GSE74703 | ZNF717 | 100131827 | 0 | 17 | 19 | |
| GSE74704 | ZNF717 | 100131827 | 1 | 13 | 6 | |
| TCGA | ZNF717 | 100131827 | 1 | 78 | 17 |
Total number of gains: 17; Total number of losses: 240; Total Number of normals: 231.
Somatic mutations of ZNF717:
Generating mutation plots.
Highly correlated genes for ZNF717:
Showing top 20/1257 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF717 | MTA3 | 0.802346 | 3 | 0 | 3 |
| ZNF717 | CCNYL1 | 0.799516 | 3 | 0 | 3 |
| ZNF717 | CNP | 0.782066 | 3 | 0 | 3 |
| ZNF717 | WHAMM | 0.775269 | 3 | 0 | 3 |
| ZNF717 | CAPN3 | 0.773699 | 3 | 0 | 3 |
| ZNF717 | GNAT2 | 0.773071 | 3 | 0 | 3 |
| ZNF717 | THAP2 | 0.768266 | 3 | 0 | 3 |
| ZNF717 | ZNF654 | 0.764335 | 4 | 0 | 3 |
| ZNF717 | HECW2 | 0.762576 | 4 | 0 | 4 |
| ZNF717 | ANKRD13A | 0.752755 | 4 | 0 | 4 |
| ZNF717 | ANO8 | 0.752407 | 3 | 0 | 3 |
| ZNF717 | TMCO4 | 0.749103 | 4 | 0 | 4 |
| ZNF717 | POLR2L | 0.747261 | 4 | 0 | 3 |
| ZNF717 | CHM | 0.742161 | 3 | 0 | 3 |
| ZNF717 | C2CD2 | 0.741974 | 3 | 0 | 3 |
| ZNF717 | PANK1 | 0.739253 | 3 | 0 | 3 |
| ZNF717 | ZNF480 | 0.73664 | 4 | 0 | 4 |
| ZNF717 | ZNF844 | 0.736414 | 7 | 0 | 7 |
| ZNF717 | PIGA | 0.734394 | 3 | 0 | 3 |
| ZNF717 | SYTL4 | 0.734287 | 3 | 0 | 3 |
For details and further investigation, click here
