| Full name: family with sequence similarity 122A | Alias Symbol: MGC17347 | ||
| Type: protein-coding gene | Cytoband: 9q21.11 | ||
| Entrez ID: 116224 | HGNC ID: HGNC:23490 | Ensembl Gene: ENSG00000187866 | OMIM ID: 617249 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FAM122A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM122A | 116224 | 226443_at | -0.7411 | 0.0351 | |
| GSE26886 | FAM122A | 116224 | 226443_at | -0.7363 | 0.0005 | |
| GSE45670 | FAM122A | 116224 | 226443_at | -0.1691 | 0.2951 | |
| GSE53622 | FAM122A | 116224 | 51290 | -0.5279 | 0.0000 | |
| GSE53624 | FAM122A | 116224 | 51290 | -0.1466 | 0.0563 | |
| GSE63941 | FAM122A | 116224 | 226443_at | 0.1376 | 0.7656 | |
| GSE77861 | FAM122A | 116224 | 226443_at | -0.1141 | 0.7436 | |
| GSE97050 | FAM122A | 116224 | A_23_P409516 | -0.3165 | 0.4098 | |
| SRP007169 | FAM122A | 116224 | RNAseq | 0.4427 | 0.3797 | |
| SRP008496 | FAM122A | 116224 | RNAseq | 0.9002 | 0.0065 | |
| SRP064894 | FAM122A | 116224 | RNAseq | -0.2554 | 0.1096 | |
| SRP133303 | FAM122A | 116224 | RNAseq | -0.5755 | 0.0000 | |
| SRP159526 | FAM122A | 116224 | RNAseq | -0.2507 | 0.3967 | |
| SRP193095 | FAM122A | 116224 | RNAseq | -0.4175 | 0.0010 | |
| SRP219564 | FAM122A | 116224 | RNAseq | -0.6347 | 0.0042 | |
| TCGA | FAM122A | 116224 | RNAseq | -0.1767 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM122A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM122A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM122A | 116224 | 6 | 10 | 14 | |
| GSE20123 | FAM122A | 116224 | 6 | 10 | 14 | |
| GSE43470 | FAM122A | 116224 | 6 | 5 | 32 | |
| GSE46452 | FAM122A | 116224 | 7 | 14 | 38 | |
| GSE47630 | FAM122A | 116224 | 1 | 19 | 20 | |
| GSE54993 | FAM122A | 116224 | 5 | 1 | 64 | |
| GSE54994 | FAM122A | 116224 | 4 | 13 | 36 | |
| GSE60625 | FAM122A | 116224 | 0 | 0 | 11 | |
| GSE74703 | FAM122A | 116224 | 5 | 4 | 27 | |
| GSE74704 | FAM122A | 116224 | 3 | 7 | 10 | |
| TCGA | FAM122A | 116224 | 18 | 28 | 50 |
Total number of gains: 61; Total number of losses: 111; Total Number of normals: 316.
Somatic mutations of FAM122A:
Generating mutation plots.
Highly correlated genes for FAM122A:
Showing top 20/818 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM122A | SPAG16 | 0.88007 | 3 | 0 | 3 |
| FAM122A | ZFC3H1 | 0.80582 | 3 | 0 | 3 |
| FAM122A | SLC22A15 | 0.796067 | 3 | 0 | 3 |
| FAM122A | HSPA4 | 0.782978 | 3 | 0 | 3 |
| FAM122A | SYTL4 | 0.781866 | 3 | 0 | 3 |
| FAM122A | CPT2 | 0.78116 | 3 | 0 | 3 |
| FAM122A | PKN2 | 0.77792 | 3 | 0 | 3 |
| FAM122A | CRYBG3 | 0.776983 | 3 | 0 | 3 |
| FAM122A | SLTM | 0.772994 | 4 | 0 | 4 |
| FAM122A | HBP1 | 0.772079 | 3 | 0 | 3 |
| FAM122A | CRYL1 | 0.770538 | 4 | 0 | 4 |
| FAM122A | ZCCHC9 | 0.770347 | 3 | 0 | 3 |
| FAM122A | BLOC1S2 | 0.770235 | 3 | 0 | 3 |
| FAM122A | LYRM7 | 0.769393 | 3 | 0 | 3 |
| FAM122A | MKRN2 | 0.768215 | 3 | 0 | 3 |
| FAM122A | CNOT1 | 0.761709 | 3 | 0 | 3 |
| FAM122A | BECN1 | 0.761452 | 4 | 0 | 4 |
| FAM122A | NCOA4 | 0.754526 | 4 | 0 | 4 |
| FAM122A | PFDN5 | 0.752369 | 3 | 0 | 3 |
| FAM122A | DIAPH1 | 0.748598 | 3 | 0 | 3 |
For details and further investigation, click here
