| Full name: transforming growth factor beta regulator 1 | Alias Symbol: FLJ14621|TB-5|NIAM | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 84897 | HGNC ID: HGNC:29551 | Ensembl Gene: ENSG00000154144 | OMIM ID: 610614 |
| Drug and gene relationship at DGIdb | |||
Expression of TBRG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBRG1 | 84897 | 226318_at | -0.0775 | 0.9040 | |
| GSE26886 | TBRG1 | 84897 | 226318_at | -1.7624 | 0.0000 | |
| GSE45670 | TBRG1 | 84897 | 226318_at | -0.2161 | 0.0911 | |
| GSE53622 | TBRG1 | 84897 | 28429 | -0.0519 | 0.5236 | |
| GSE53624 | TBRG1 | 84897 | 28429 | -0.0231 | 0.7164 | |
| GSE63941 | TBRG1 | 84897 | 226318_at | -0.2573 | 0.5975 | |
| GSE77861 | TBRG1 | 84897 | 226318_at | 0.1857 | 0.5731 | |
| GSE97050 | TBRG1 | 84897 | A_24_P21752 | -0.1724 | 0.4144 | |
| SRP007169 | TBRG1 | 84897 | RNAseq | 0.0146 | 0.9709 | |
| SRP008496 | TBRG1 | 84897 | RNAseq | 0.2345 | 0.3276 | |
| SRP064894 | TBRG1 | 84897 | RNAseq | -0.1134 | 0.3918 | |
| SRP133303 | TBRG1 | 84897 | RNAseq | -0.2917 | 0.0193 | |
| SRP159526 | TBRG1 | 84897 | RNAseq | -0.7017 | 0.0014 | |
| SRP193095 | TBRG1 | 84897 | RNAseq | -0.4061 | 0.0000 | |
| SRP219564 | TBRG1 | 84897 | RNAseq | -0.2603 | 0.3896 | |
| TCGA | TBRG1 | 84897 | RNAseq | -0.2858 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TBRG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBRG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBRG1 | 84897 | 0 | 13 | 17 | |
| GSE20123 | TBRG1 | 84897 | 0 | 13 | 17 | |
| GSE43470 | TBRG1 | 84897 | 2 | 7 | 34 | |
| GSE46452 | TBRG1 | 84897 | 3 | 26 | 30 | |
| GSE47630 | TBRG1 | 84897 | 2 | 19 | 19 | |
| GSE54993 | TBRG1 | 84897 | 10 | 0 | 60 | |
| GSE54994 | TBRG1 | 84897 | 5 | 19 | 29 | |
| GSE60625 | TBRG1 | 84897 | 0 | 3 | 8 | |
| GSE74703 | TBRG1 | 84897 | 1 | 5 | 30 | |
| GSE74704 | TBRG1 | 84897 | 0 | 9 | 11 | |
| TCGA | TBRG1 | 84897 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of TBRG1:
Generating mutation plots.
Highly correlated genes for TBRG1:
Showing top 20/142 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBRG1 | BRWD3 | 0.840962 | 3 | 0 | 3 |
| TBRG1 | ZNF654 | 0.805118 | 3 | 0 | 3 |
| TBRG1 | SNRNP200 | 0.797253 | 3 | 0 | 3 |
| TBRG1 | ANAPC4 | 0.78246 | 3 | 0 | 3 |
| TBRG1 | CDK5RAP3 | 0.780209 | 3 | 0 | 3 |
| TBRG1 | CLN8 | 0.778841 | 3 | 0 | 3 |
| TBRG1 | ITFG2 | 0.77159 | 3 | 0 | 3 |
| TBRG1 | ATP6V1H | 0.76776 | 3 | 0 | 3 |
| TBRG1 | PPIG | 0.760208 | 3 | 0 | 3 |
| TBRG1 | WDR37 | 0.75753 | 3 | 0 | 3 |
| TBRG1 | STX17 | 0.754914 | 3 | 0 | 3 |
| TBRG1 | AKAP17A | 0.752941 | 3 | 0 | 3 |
| TBRG1 | NUDT3 | 0.75181 | 3 | 0 | 3 |
| TBRG1 | TMEM43 | 0.750386 | 3 | 0 | 3 |
| TBRG1 | ZNF274 | 0.746817 | 3 | 0 | 3 |
| TBRG1 | GPD2 | 0.745961 | 3 | 0 | 3 |
| TBRG1 | METTL14 | 0.744583 | 3 | 0 | 3 |
| TBRG1 | CREBZF | 0.744047 | 3 | 0 | 3 |
| TBRG1 | UFM1 | 0.74311 | 3 | 0 | 3 |
| TBRG1 | NDUFB3 | 0.742407 | 3 | 0 | 3 |
For details and further investigation, click here
