| Full name: zinc and ring finger 2 | Alias Symbol: RNF202 | ||
| Type: protein-coding gene | Cytoband: 7p14.3 | ||
| Entrez ID: 223082 | HGNC ID: HGNC:22316 | Ensembl Gene: ENSG00000180233 | OMIM ID: 612061 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNRF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNRF2 | 223082 | 226261_at | 0.6964 | 0.2555 | |
| GSE26886 | ZNRF2 | 223082 | 226261_at | 0.2902 | 0.1717 | |
| GSE45670 | ZNRF2 | 223082 | 226261_at | 0.4988 | 0.0131 | |
| GSE53622 | ZNRF2 | 223082 | 8505 | 0.0881 | 0.3239 | |
| GSE53624 | ZNRF2 | 223082 | 8505 | -0.1026 | 0.1809 | |
| GSE63941 | ZNRF2 | 223082 | 226261_at | 1.3219 | 0.0182 | |
| GSE77861 | ZNRF2 | 223082 | 226261_at | -0.3206 | 0.1050 | |
| GSE97050 | ZNRF2 | A_21_P0000536 | -0.3635 | 0.1525 | ||
| SRP007169 | ZNRF2 | 223082 | RNAseq | -1.5139 | 0.0000 | |
| SRP008496 | ZNRF2 | 223082 | RNAseq | -0.7836 | 0.0041 | |
| SRP064894 | ZNRF2 | 223082 | RNAseq | -0.1988 | 0.3458 | |
| SRP133303 | ZNRF2 | 223082 | RNAseq | 0.4828 | 0.0071 | |
| SRP159526 | ZNRF2 | 223082 | RNAseq | -0.4103 | 0.3355 | |
| SRP193095 | ZNRF2 | 223082 | RNAseq | -0.2818 | 0.0053 | |
| SRP219564 | ZNRF2 | 223082 | RNAseq | -0.4819 | 0.3439 | |
| TCGA | ZNRF2 | 223082 | RNAseq | -0.0310 | 0.5759 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ZNRF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNRF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNRF2 | 223082 | 15 | 0 | 15 | |
| GSE20123 | ZNRF2 | 223082 | 15 | 0 | 15 | |
| GSE43470 | ZNRF2 | 223082 | 4 | 0 | 39 | |
| GSE46452 | ZNRF2 | 223082 | 11 | 1 | 47 | |
| GSE47630 | ZNRF2 | 223082 | 8 | 1 | 31 | |
| GSE54993 | ZNRF2 | 223082 | 0 | 6 | 64 | |
| GSE54994 | ZNRF2 | 223082 | 19 | 3 | 31 | |
| GSE60625 | ZNRF2 | 223082 | 0 | 0 | 11 | |
| GSE74703 | ZNRF2 | 223082 | 4 | 0 | 32 | |
| GSE74704 | ZNRF2 | 223082 | 9 | 0 | 11 | |
| TCGA | ZNRF2 | 223082 | 55 | 7 | 34 |
Total number of gains: 140; Total number of losses: 18; Total Number of normals: 330.
Somatic mutations of ZNRF2:
Generating mutation plots.
Highly correlated genes for ZNRF2:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNRF2 | NRG4 | 0.754601 | 3 | 0 | 3 |
| ZNRF2 | FABP6 | 0.733109 | 3 | 0 | 3 |
| ZNRF2 | SBNO2 | 0.728034 | 4 | 0 | 3 |
| ZNRF2 | TMEM102 | 0.721987 | 3 | 0 | 3 |
| ZNRF2 | HOXD9 | 0.719025 | 3 | 0 | 3 |
| ZNRF2 | HES2 | 0.716856 | 3 | 0 | 3 |
| ZNRF2 | ELMO3 | 0.706355 | 3 | 0 | 3 |
| ZNRF2 | PPA2 | 0.706112 | 3 | 0 | 3 |
| ZNRF2 | NKPD1 | 0.704651 | 3 | 0 | 3 |
| ZNRF2 | OTUB2 | 0.703597 | 3 | 0 | 3 |
| ZNRF2 | SLC34A1 | 0.694596 | 3 | 0 | 3 |
| ZNRF2 | GNL1 | 0.688642 | 3 | 0 | 3 |
| ZNRF2 | IL23A | 0.682315 | 3 | 0 | 3 |
| ZNRF2 | MC5R | 0.667447 | 3 | 0 | 3 |
| ZNRF2 | BTBD8 | 0.659259 | 3 | 0 | 3 |
| ZNRF2 | ZNF77 | 0.634248 | 4 | 0 | 3 |
| ZNRF2 | MICALL1 | 0.621449 | 4 | 0 | 3 |
| ZNRF2 | TLE3 | 0.607221 | 3 | 0 | 3 |
| ZNRF2 | ST14 | 0.604014 | 3 | 0 | 3 |
| ZNRF2 | TTC39A | 0.599145 | 4 | 0 | 3 |
For details and further investigation, click here
