| Full name: melanocortin 5 receptor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18p11.21 | ||
| Entrez ID: 4161 | HGNC ID: HGNC:6933 | Ensembl Gene: ENSG00000176136 | OMIM ID: 600042 |
| Drug and gene relationship at DGIdb | |||
Expression of MC5R:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MC5R | 4161 | 208565_at | -0.3917 | 0.2919 | |
| GSE20347 | MC5R | 4161 | 208565_at | -0.1051 | 0.2601 | |
| GSE23400 | MC5R | 4161 | 208565_at | -0.1911 | 0.0000 | |
| GSE26886 | MC5R | 4161 | 208565_at | -0.1974 | 0.0916 | |
| GSE29001 | MC5R | 4161 | 208565_at | -0.3202 | 0.0607 | |
| GSE38129 | MC5R | 4161 | 208565_at | -0.1821 | 0.1410 | |
| GSE45670 | MC5R | 4161 | 208565_at | -0.1346 | 0.0915 | |
| GSE53622 | MC5R | 4161 | 36919 | -0.9754 | 0.0000 | |
| GSE53624 | MC5R | 4161 | 36919 | -0.4589 | 0.0000 | |
| GSE63941 | MC5R | 4161 | 208565_at | 0.0778 | 0.7115 | |
| GSE77861 | MC5R | 4161 | 208565_at | -0.2425 | 0.0207 | |
| GSE97050 | MC5R | 4161 | A_23_P50039 | -0.4796 | 0.2584 | |
| TCGA | MC5R | 4161 | RNAseq | -0.7879 | 0.4227 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MC5R expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MC5R:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MC5R | 4161 | 5 | 3 | 22 | |
| GSE20123 | MC5R | 4161 | 5 | 3 | 22 | |
| GSE43470 | MC5R | 4161 | 0 | 6 | 37 | |
| GSE46452 | MC5R | 4161 | 3 | 21 | 35 | |
| GSE47630 | MC5R | 4161 | 7 | 17 | 16 | |
| GSE54993 | MC5R | 4161 | 6 | 2 | 62 | |
| GSE54994 | MC5R | 4161 | 8 | 8 | 37 | |
| GSE60625 | MC5R | 4161 | 0 | 4 | 7 | |
| GSE74703 | MC5R | 4161 | 0 | 4 | 32 | |
| GSE74704 | MC5R | 4161 | 3 | 2 | 15 | |
| TCGA | MC5R | 4161 | 27 | 23 | 46 |
Total number of gains: 64; Total number of losses: 93; Total Number of normals: 331.
Somatic mutations of MC5R:
Generating mutation plots.
Highly correlated genes for MC5R:
Showing top 20/851 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MC5R | UMOD | 0.721661 | 4 | 0 | 4 |
| MC5R | GDF2 | 0.71682 | 3 | 0 | 3 |
| MC5R | PAX8 | 0.716376 | 6 | 0 | 6 |
| MC5R | TM6SF2 | 0.712993 | 4 | 0 | 3 |
| MC5R | MASP1 | 0.705207 | 3 | 0 | 3 |
| MC5R | AQP4 | 0.703488 | 4 | 0 | 4 |
| MC5R | PDYN | 0.7026 | 5 | 0 | 5 |
| MC5R | INHBC | 0.700172 | 3 | 0 | 3 |
| MC5R | PSG9 | 0.697777 | 4 | 0 | 4 |
| MC5R | OR1J4 | 0.694862 | 3 | 0 | 3 |
| MC5R | KRT2 | 0.692327 | 5 | 0 | 5 |
| MC5R | FGF6 | 0.691488 | 5 | 0 | 5 |
| MC5R | EPB42 | 0.685403 | 6 | 0 | 6 |
| MC5R | GPR182 | 0.68445 | 5 | 0 | 5 |
| MC5R | PAX3 | 0.683617 | 5 | 0 | 4 |
| MC5R | MAGEA8 | 0.678385 | 3 | 0 | 3 |
| MC5R | G6PC | 0.678306 | 3 | 0 | 3 |
| MC5R | IL9R | 0.677965 | 5 | 0 | 5 |
| MC5R | SLC6A5 | 0.676939 | 3 | 0 | 3 |
| MC5R | TUBA8 | 0.676065 | 5 | 0 | 5 |
For details and further investigation, click here
