| Full name: BTB domain containing 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p22.1 | ||
| Entrez ID: 284697 | HGNC ID: HGNC:21019 | Ensembl Gene: ENSG00000189195 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of BTBD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTBD8 | 284697 | 1569693_at | 0.0526 | 0.8577 | |
| GSE26886 | BTBD8 | 284697 | 1569693_at | -0.0619 | 0.5157 | |
| GSE45670 | BTBD8 | 284697 | 1569693_at | 0.0755 | 0.2842 | |
| GSE53622 | BTBD8 | 284697 | 17037 | -0.3354 | 0.0045 | |
| GSE53624 | BTBD8 | 284697 | 17037 | -0.3449 | 0.0000 | |
| GSE63941 | BTBD8 | 284697 | 1569693_at | 0.3400 | 0.1882 | |
| GSE77861 | BTBD8 | 284697 | 1569693_at | -0.0512 | 0.4376 | |
| GSE97050 | BTBD8 | 284697 | A_24_P564030 | -0.0742 | 0.7529 | |
| SRP133303 | BTBD8 | 284697 | RNAseq | -0.1781 | 0.5987 | |
| SRP193095 | BTBD8 | 284697 | RNAseq | -0.3503 | 0.0968 | |
| TCGA | BTBD8 | 284697 | RNAseq | -0.3565 | 0.3256 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BTBD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTBD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTBD8 | 284697 | 0 | 8 | 22 | |
| GSE20123 | BTBD8 | 284697 | 0 | 8 | 22 | |
| GSE43470 | BTBD8 | 284697 | 2 | 5 | 36 | |
| GSE46452 | BTBD8 | 284697 | 1 | 1 | 57 | |
| GSE47630 | BTBD8 | 284697 | 8 | 5 | 27 | |
| GSE54993 | BTBD8 | 284697 | 0 | 1 | 69 | |
| GSE54994 | BTBD8 | 284697 | 6 | 3 | 44 | |
| GSE60625 | BTBD8 | 284697 | 0 | 0 | 11 | |
| GSE74703 | BTBD8 | 284697 | 1 | 4 | 31 | |
| GSE74704 | BTBD8 | 284697 | 0 | 5 | 15 | |
| TCGA | BTBD8 | 284697 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 64; Total Number of normals: 400.
Somatic mutations of BTBD8:
Generating mutation plots.
Highly correlated genes for BTBD8:
Showing top 20/42 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTBD8 | GPT | 0.808136 | 3 | 0 | 3 |
| BTBD8 | CD247 | 0.75732 | 3 | 0 | 3 |
| BTBD8 | CEMP1 | 0.752119 | 3 | 0 | 3 |
| BTBD8 | AGAP2 | 0.745136 | 3 | 0 | 3 |
| BTBD8 | ADAMTS13 | 0.726291 | 3 | 0 | 3 |
| BTBD8 | CAPN13 | 0.713091 | 3 | 0 | 3 |
| BTBD8 | SIL1 | 0.69364 | 3 | 0 | 3 |
| BTBD8 | HDAC8 | 0.692097 | 3 | 0 | 3 |
| BTBD8 | MEGF10 | 0.686254 | 3 | 0 | 3 |
| BTBD8 | SIGLEC7 | 0.680569 | 3 | 0 | 3 |
| BTBD8 | CPNE9 | 0.670747 | 3 | 0 | 3 |
| BTBD8 | OPRD1 | 0.662399 | 3 | 0 | 3 |
| BTBD8 | TRH | 0.659663 | 3 | 0 | 3 |
| BTBD8 | ZNRF2 | 0.659259 | 3 | 0 | 3 |
| BTBD8 | PHLDB3 | 0.649823 | 3 | 0 | 3 |
| BTBD8 | ZNF135 | 0.644407 | 3 | 0 | 3 |
| BTBD8 | TUBGCP6 | 0.641287 | 4 | 0 | 3 |
| BTBD8 | TMEM221 | 0.632433 | 3 | 0 | 3 |
| BTBD8 | TPH1 | 0.632147 | 4 | 0 | 3 |
| BTBD8 | SMC1B | 0.619401 | 3 | 0 | 3 |
For details and further investigation, click here
