| Full name: RFX family member 8, lacking RFX DNA binding domain | Alias Symbol: FLJ42986 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 731220 | HGNC ID: HGNC:37253 | Ensembl Gene: ENSG00000196460 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RFX8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | RFX8 | 731220 | 73644 | 0.9323 | 0.0000 | |
| GSE53624 | RFX8 | 731220 | 73644 | 0.8254 | 0.0000 | |
| GSE97050 | RFX8 | 731220 | A_33_P3281741 | 0.1246 | 0.6463 | |
| SRP064894 | RFX8 | 731220 | RNAseq | 2.8767 | 0.0000 | |
| SRP133303 | RFX8 | 731220 | RNAseq | 2.7829 | 0.0000 | |
| SRP159526 | RFX8 | 731220 | RNAseq | 1.8497 | 0.0006 | |
| SRP219564 | RFX8 | 731220 | RNAseq | 1.8269 | 0.0061 | |
| TCGA | RFX8 | 731220 | RNAseq | 3.2797 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by RFX8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFX8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFX8 | 731220 | 5 | 2 | 23 | |
| GSE20123 | RFX8 | 731220 | 5 | 2 | 23 | |
| GSE43470 | RFX8 | 731220 | 5 | 1 | 37 | |
| GSE46452 | RFX8 | 731220 | 1 | 4 | 54 | |
| GSE47630 | RFX8 | 731220 | 7 | 0 | 33 | |
| GSE54993 | RFX8 | 731220 | 0 | 6 | 64 | |
| GSE54994 | RFX8 | 731220 | 11 | 0 | 42 | |
| GSE60625 | RFX8 | 731220 | 0 | 3 | 8 | |
| GSE74703 | RFX8 | 731220 | 5 | 1 | 30 | |
| GSE74704 | RFX8 | 731220 | 3 | 1 | 16 | |
| TCGA | RFX8 | 731220 | 35 | 5 | 56 |
Total number of gains: 77; Total number of losses: 25; Total Number of normals: 386.
Somatic mutations of RFX8:
Generating mutation plots.
Highly correlated genes for RFX8:
Showing top 20/95 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFX8 | C1QTNF6 | 0.783199 | 3 | 0 | 3 |
| RFX8 | GPRIN1 | 0.76381 | 3 | 0 | 3 |
| RFX8 | DBF4B | 0.758307 | 3 | 0 | 3 |
| RFX8 | KIF26B | 0.755333 | 3 | 0 | 3 |
| RFX8 | TSPO2 | 0.75237 | 3 | 0 | 3 |
| RFX8 | NPM2 | 0.744172 | 3 | 0 | 3 |
| RFX8 | KLK3 | 0.74317 | 3 | 0 | 3 |
| RFX8 | KIF19 | 0.743152 | 3 | 0 | 3 |
| RFX8 | DNMT3B | 0.741692 | 3 | 0 | 3 |
| RFX8 | COL27A1 | 0.735924 | 3 | 0 | 3 |
| RFX8 | KIF4A | 0.734006 | 3 | 0 | 3 |
| RFX8 | MYLK2 | 0.733139 | 3 | 0 | 3 |
| RFX8 | ZNRF4 | 0.73128 | 3 | 0 | 3 |
| RFX8 | GALNS | 0.730016 | 3 | 0 | 3 |
| RFX8 | LRFN4 | 0.722964 | 3 | 0 | 3 |
| RFX8 | SALL4 | 0.720425 | 3 | 0 | 3 |
| RFX8 | PMEPA1 | 0.719595 | 3 | 0 | 3 |
| RFX8 | ATAD3C | 0.718157 | 3 | 0 | 3 |
| RFX8 | NAT14 | 0.713091 | 3 | 0 | 3 |
| RFX8 | YEATS2 | 0.712899 | 3 | 0 | 3 |
For details and further investigation, click here
