| Full name: solute carrier family 6 member 13 | Alias Symbol: GAT2 | ||
| Type: protein-coding gene | Cytoband: 12p13.33 | ||
| Entrez ID: 6540 | HGNC ID: HGNC:11046 | Ensembl Gene: ENSG00000010379 | OMIM ID: 615097 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC6A13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A13 | 6540 | 207184_at | -0.1213 | 0.7789 | |
| GSE20347 | SLC6A13 | 6540 | 207184_at | 0.0192 | 0.8365 | |
| GSE23400 | SLC6A13 | 6540 | 207184_at | -0.1187 | 0.0067 | |
| GSE26886 | SLC6A13 | 6540 | 207184_at | 0.1453 | 0.2305 | |
| GSE29001 | SLC6A13 | 6540 | 207184_at | -0.2084 | 0.2673 | |
| GSE38129 | SLC6A13 | 6540 | 207184_at | -0.0350 | 0.7201 | |
| GSE45670 | SLC6A13 | 6540 | 207184_at | 0.0473 | 0.6775 | |
| GSE53622 | SLC6A13 | 6540 | 53484 | 0.0996 | 0.0520 | |
| GSE53624 | SLC6A13 | 6540 | 53484 | -0.0073 | 0.9400 | |
| GSE63941 | SLC6A13 | 6540 | 207184_at | 0.4086 | 0.0370 | |
| GSE77861 | SLC6A13 | 6540 | 207184_at | -0.0924 | 0.5226 | |
| GSE97050 | SLC6A13 | 6540 | A_23_P64980 | 0.1147 | 0.5860 | |
| TCGA | SLC6A13 | 6540 | RNAseq | 2.6733 | 0.0011 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC6A13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A13 | 6540 | 7 | 4 | 19 | |
| GSE20123 | SLC6A13 | 6540 | 7 | 4 | 19 | |
| GSE43470 | SLC6A13 | 6540 | 8 | 3 | 32 | |
| GSE46452 | SLC6A13 | 6540 | 10 | 1 | 48 | |
| GSE47630 | SLC6A13 | 6540 | 12 | 2 | 26 | |
| GSE54993 | SLC6A13 | 6540 | 1 | 10 | 59 | |
| GSE54994 | SLC6A13 | 6540 | 10 | 2 | 41 | |
| GSE60625 | SLC6A13 | 6540 | 0 | 1 | 10 | |
| GSE74703 | SLC6A13 | 6540 | 7 | 2 | 27 | |
| GSE74704 | SLC6A13 | 6540 | 4 | 2 | 14 | |
| TCGA | SLC6A13 | 6540 | 41 | 7 | 48 |
Total number of gains: 107; Total number of losses: 38; Total Number of normals: 343.
Somatic mutations of SLC6A13:
Generating mutation plots.
Highly correlated genes for SLC6A13:
Showing top 20/1030 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A13 | STX1B | 0.804174 | 3 | 0 | 3 |
| SLC6A13 | LRCH4 | 0.795695 | 3 | 0 | 3 |
| SLC6A13 | TSSK3 | 0.774887 | 4 | 0 | 4 |
| SLC6A13 | ZNF81 | 0.760659 | 3 | 0 | 3 |
| SLC6A13 | LACRT | 0.752724 | 3 | 0 | 3 |
| SLC6A13 | RAB11FIP4 | 0.752551 | 3 | 0 | 3 |
| SLC6A13 | MEGF10 | 0.750213 | 3 | 0 | 3 |
| SLC6A13 | PRAF2 | 0.749473 | 3 | 0 | 3 |
| SLC6A13 | FAM71F1 | 0.739496 | 3 | 0 | 3 |
| SLC6A13 | ZNRF4 | 0.731271 | 3 | 0 | 3 |
| SLC6A13 | HSD3B1 | 0.727862 | 5 | 0 | 5 |
| SLC6A13 | HBM | 0.725077 | 3 | 0 | 3 |
| SLC6A13 | SNORA71A | 0.723127 | 3 | 0 | 3 |
| SLC6A13 | KIR3DL3 | 0.717753 | 5 | 0 | 5 |
| SLC6A13 | PTK6 | 0.717584 | 3 | 0 | 3 |
| SLC6A13 | LRTM2 | 0.706504 | 3 | 0 | 3 |
| SLC6A13 | ADRA1A | 0.69983 | 5 | 0 | 5 |
| SLC6A13 | CELF3 | 0.699528 | 8 | 0 | 6 |
| SLC6A13 | PSG9 | 0.697918 | 4 | 0 | 4 |
| SLC6A13 | MRAP | 0.697438 | 3 | 0 | 3 |
For details and further investigation, click here
