| Full name: lens intrinsic membrane protein 2 | Alias Symbol: MP19|MP17 | ||
| Type: protein-coding gene | Cytoband: 19q13.4 | ||
| Entrez ID: 3982 | HGNC ID: HGNC:6610 | Ensembl Gene: ENSG00000105370 | OMIM ID: 154045 |
| Drug and gene relationship at DGIdb | |||
Expression of LIM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIM2 | 3982 | 220519_s_at | 0.2002 | 0.7330 | |
| GSE20347 | LIM2 | 3982 | 220519_s_at | -0.0562 | 0.4051 | |
| GSE23400 | LIM2 | 3982 | 220519_s_at | -0.0867 | 0.0033 | |
| GSE26886 | LIM2 | 3982 | 220519_s_at | 0.3244 | 0.0261 | |
| GSE29001 | LIM2 | 3982 | 220519_s_at | -0.0196 | 0.9018 | |
| GSE38129 | LIM2 | 3982 | 220519_s_at | -0.0360 | 0.6717 | |
| GSE45670 | LIM2 | 3982 | 220519_s_at | 0.2612 | 0.3811 | |
| GSE53622 | LIM2 | 3982 | 127998 | 0.5376 | 0.0000 | |
| GSE53624 | LIM2 | 3982 | 127998 | 0.4931 | 0.0000 | |
| GSE63941 | LIM2 | 3982 | 220519_s_at | -0.0079 | 0.9617 | |
| GSE77861 | LIM2 | 3982 | 220519_s_at | -0.0879 | 0.5895 | |
| GSE97050 | LIM2 | 3982 | A_23_P130435 | 0.0024 | 0.9916 | |
| TCGA | LIM2 | 3982 | RNAseq | 3.3788 | 0.0181 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LIM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LIM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIM2 | 3982 | 3 | 4 | 23 | |
| GSE20123 | LIM2 | 3982 | 3 | 3 | 24 | |
| GSE43470 | LIM2 | 3982 | 3 | 12 | 28 | |
| GSE46452 | LIM2 | 3982 | 45 | 1 | 13 | |
| GSE47630 | LIM2 | 3982 | 9 | 6 | 25 | |
| GSE54993 | LIM2 | 3982 | 17 | 4 | 49 | |
| GSE54994 | LIM2 | 3982 | 4 | 14 | 35 | |
| GSE60625 | LIM2 | 3982 | 9 | 0 | 2 | |
| GSE74703 | LIM2 | 3982 | 3 | 8 | 25 | |
| GSE74704 | LIM2 | 3982 | 3 | 1 | 16 | |
| TCGA | LIM2 | 3982 | 14 | 19 | 63 |
Total number of gains: 113; Total number of losses: 72; Total Number of normals: 303.
Somatic mutations of LIM2:
Generating mutation plots.
Highly correlated genes for LIM2:
Showing top 20/531 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIM2 | IL1F10 | 0.843322 | 3 | 0 | 3 |
| LIM2 | MGAT5B | 0.829451 | 3 | 0 | 3 |
| LIM2 | GPC2 | 0.819065 | 3 | 0 | 3 |
| LIM2 | PGC | 0.815348 | 3 | 0 | 3 |
| LIM2 | RASL10B | 0.80316 | 3 | 0 | 3 |
| LIM2 | C20orf141 | 0.794251 | 3 | 0 | 3 |
| LIM2 | REG3A | 0.791823 | 4 | 0 | 4 |
| LIM2 | DUSP15 | 0.781201 | 3 | 0 | 3 |
| LIM2 | MPP2 | 0.774251 | 3 | 0 | 3 |
| LIM2 | FOXA3 | 0.757243 | 3 | 0 | 3 |
| LIM2 | OLIG3 | 0.756632 | 3 | 0 | 3 |
| LIM2 | WDR90 | 0.75139 | 3 | 0 | 3 |
| LIM2 | GPR39 | 0.744906 | 4 | 0 | 3 |
| LIM2 | STK11 | 0.744897 | 3 | 0 | 3 |
| LIM2 | PASD1 | 0.734718 | 3 | 0 | 3 |
| LIM2 | ATP2B3 | 0.730741 | 3 | 0 | 3 |
| LIM2 | C19orf81 | 0.721347 | 3 | 0 | 3 |
| LIM2 | ACBD4 | 0.721061 | 3 | 0 | 3 |
| LIM2 | NOXA1 | 0.720595 | 3 | 0 | 3 |
| LIM2 | LRRN4 | 0.719245 | 3 | 0 | 3 |
For details and further investigation, click here
