| Full name: zona pellucida glycoprotein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 22917 | HGNC ID: HGNC:13187 | Ensembl Gene: ENSG00000149506 | OMIM ID: 195000 |
| Drug and gene relationship at DGIdb | |||
Expression of ZP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZP1 | 22917 | 237335_at | -0.1906 | 0.3911 | |
| GSE26886 | ZP1 | 22917 | 237335_at | 0.1115 | 0.4660 | |
| GSE45670 | ZP1 | 22917 | 237335_at | 0.2220 | 0.0662 | |
| GSE53622 | ZP1 | 22917 | 34730 | -0.1461 | 0.2786 | |
| GSE53624 | ZP1 | 22917 | 34730 | 0.2648 | 0.0623 | |
| GSE63941 | ZP1 | 22917 | 237335_at | 0.1409 | 0.5220 | |
| GSE77861 | ZP1 | 22917 | 237335_at | -0.0739 | 0.7527 | |
| TCGA | ZP1 | 22917 | RNAseq | 0.6706 | 0.4808 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZP1 | 22917 | 2 | 5 | 23 | |
| GSE20123 | ZP1 | 22917 | 2 | 5 | 23 | |
| GSE43470 | ZP1 | 22917 | 2 | 6 | 35 | |
| GSE46452 | ZP1 | 22917 | 8 | 4 | 47 | |
| GSE47630 | ZP1 | 22917 | 3 | 8 | 29 | |
| GSE54993 | ZP1 | 22917 | 3 | 0 | 67 | |
| GSE54994 | ZP1 | 22917 | 5 | 5 | 43 | |
| GSE60625 | ZP1 | 22917 | 0 | 3 | 8 | |
| GSE74703 | ZP1 | 22917 | 2 | 3 | 31 | |
| GSE74704 | ZP1 | 22917 | 2 | 3 | 15 | |
| TCGA | ZP1 | 22917 | 15 | 10 | 71 |
Total number of gains: 44; Total number of losses: 52; Total Number of normals: 392.
Somatic mutations of ZP1:
Generating mutation plots.
Highly correlated genes for ZP1:
Showing all 17 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZP1 | CCIN | 0.634283 | 4 | 0 | 4 |
| ZP1 | HCN2 | 0.627742 | 4 | 0 | 3 |
| ZP1 | CRYBA2 | 0.616345 | 3 | 0 | 3 |
| ZP1 | EPO | 0.613402 | 3 | 0 | 3 |
| ZP1 | RNF31 | 0.613305 | 3 | 0 | 3 |
| ZP1 | VRTN | 0.607118 | 3 | 0 | 3 |
| ZP1 | INS | 0.599647 | 3 | 0 | 3 |
| ZP1 | TFAP2D | 0.599524 | 3 | 0 | 3 |
| ZP1 | USP2 | 0.598242 | 4 | 0 | 3 |
| ZP1 | UNK | 0.597846 | 3 | 0 | 3 |
| ZP1 | ARHGAP44 | 0.588419 | 3 | 0 | 3 |
| ZP1 | CABP7 | 0.573634 | 3 | 0 | 3 |
| ZP1 | FKBP6 | 0.571984 | 3 | 0 | 3 |
| ZP1 | KIF25 | 0.55116 | 4 | 0 | 3 |
| ZP1 | VWCE | 0.538217 | 4 | 0 | 3 |
| ZP1 | JSRP1 | 0.537496 | 3 | 0 | 3 |
| ZP1 | NEU4 | 0.533002 | 3 | 0 | 3 |
For details and further investigation, click here
