UNK

 

Full name: unk zinc finger Alias Symbol: KIAA1753
Type: protein-coding gene Cytoband: 17q25.3
Entrez ID: 85451 HGNC ID: HGNC:29369 Ensembl Gene: ENSG00000132478 OMIM ID: 616375
Drug and gene relationship at DGIdb

 

Expression of UNK:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UNK 85451 228357_at -0.8959 0.0579
GSE26886 UNK 85451 226376_at 0.1801 0.2312
GSE45670 UNK 85451 228357_at -0.2188 0.2538
GSE53622 UNK 85451 25424 -0.6340 0.0000
GSE53624 UNK 85451 99378 -0.5083 0.0000
GSE63941 UNK 85451 228357_at 0.5948 0.1608
GSE77861 UNK 85451 226376_at -0.0295 0.8418
GSE97050 UNK 85451 A_32_P514790 0.1145 0.6517
SRP007169 UNK 85451 RNAseq -0.5559 0.1894
SRP008496 UNK 85451 RNAseq -0.7836 0.0137
SRP064894 UNK 85451 RNAseq -0.1509 0.3883
SRP133303 UNK 85451 RNAseq 0.2117 0.5275
SRP159526 UNK 85451 RNAseq -0.0572 0.8515
SRP193095 UNK 85451 RNAseq -0.5101 0.0000
SRP219564 UNK 85451 RNAseq -0.4564 0.0764
TCGA UNK 85451 RNAseq 0.0320 0.5228

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by UNK expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of UNK:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UNK 85451 7 2 21
GSE20123 UNK 85451 7 2 21
GSE43470 UNK 85451 5 3 35
GSE46452 UNK 85451 34 0 25
GSE47630 UNK 85451 8 1 31
GSE54993 UNK 85451 2 5 63
GSE54994 UNK 85451 10 4 39
GSE60625 UNK 85451 6 0 5
GSE74703 UNK 85451 5 1 30
GSE74704 UNK 85451 5 1 14
TCGA UNK 85451 32 9 55

Total number of gains: 121; Total number of losses: 28; Total Number of normals: 339.  


 

Somatic mutations of UNK:

 

Generating mutation plots.

 

Highly correlated genes for UNK:

 

Showing top 20/382 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UNKACY10.788026303
UNKC9orf850.787299303
UNKIQCC0.777486303
UNKGPR1320.756353303
UNKRUFY10.754689303
UNKTMEM190.738423303
UNKANKRD90.733283303
UNKXRCC10.726863303
UNKRAB140.724038404
UNKSIK10.722994303
UNKTXNL10.722007303
UNKCCDC970.721442404
UNKSYNRG0.719106303
UNKSPTLC10.715508303
UNKGPR1080.713601303
UNKHKDC10.711902403
UNKZNF2660.711049303
UNKCOG10.710242303
UNKGMPPB0.706224303
UNKUSP250.705505403

For details and further investigation, click here