| Full name: neuraminidase 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 129807 | HGNC ID: HGNC:21328 | Ensembl Gene: ENSG00000204099 | OMIM ID: 608527 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NEU4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEU4 | 129807 | 222957_at | -0.0116 | 0.9700 | |
| GSE26886 | NEU4 | 129807 | 222957_at | 0.1984 | 0.0496 | |
| GSE45670 | NEU4 | 129807 | 222957_at | 0.1199 | 0.0777 | |
| GSE53622 | NEU4 | 129807 | 90203 | 0.1212 | 0.1560 | |
| GSE53624 | NEU4 | 129807 | 90203 | -0.1410 | 0.4331 | |
| GSE63941 | NEU4 | 129807 | 222957_at | 0.1976 | 0.1334 | |
| GSE77861 | NEU4 | 129807 | 222957_at | -0.0445 | 0.7609 | |
| SRP219564 | NEU4 | 129807 | RNAseq | 1.4092 | 0.0869 | |
| TCGA | NEU4 | 129807 | RNAseq | -0.1445 | 0.8065 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NEU4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEU4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEU4 | 129807 | 1 | 12 | 17 | |
| GSE20123 | NEU4 | 129807 | 1 | 12 | 17 | |
| GSE43470 | NEU4 | 129807 | 1 | 9 | 33 | |
| GSE46452 | NEU4 | 129807 | 0 | 5 | 54 | |
| GSE47630 | NEU4 | 129807 | 4 | 5 | 31 | |
| GSE54993 | NEU4 | 129807 | 4 | 3 | 63 | |
| GSE54994 | NEU4 | 129807 | 8 | 9 | 36 | |
| GSE60625 | NEU4 | 129807 | 0 | 3 | 8 | |
| GSE74703 | NEU4 | 129807 | 1 | 7 | 28 | |
| GSE74704 | NEU4 | 129807 | 1 | 5 | 14 | |
| TCGA | NEU4 | 129807 | 11 | 29 | 56 |
Total number of gains: 32; Total number of losses: 99; Total Number of normals: 357.
Somatic mutations of NEU4:
Generating mutation plots.
Highly correlated genes for NEU4:
Showing top 20/102 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEU4 | APOC2 | 0.698448 | 3 | 0 | 3 |
| NEU4 | JSRP1 | 0.692106 | 3 | 0 | 3 |
| NEU4 | TUT1 | 0.688834 | 3 | 0 | 3 |
| NEU4 | NOXA1 | 0.665415 | 3 | 0 | 3 |
| NEU4 | DUX1 | 0.659362 | 3 | 0 | 3 |
| NEU4 | REG3A | 0.655734 | 3 | 0 | 3 |
| NEU4 | CCDC70 | 0.655413 | 3 | 0 | 3 |
| NEU4 | ST8SIA2 | 0.655144 | 3 | 0 | 3 |
| NEU4 | NKAIN1 | 0.648389 | 3 | 0 | 3 |
| NEU4 | RBBP8NL | 0.647895 | 4 | 0 | 3 |
| NEU4 | VWCE | 0.647799 | 3 | 0 | 3 |
| NEU4 | MIR142 | 0.641988 | 3 | 0 | 3 |
| NEU4 | HCN2 | 0.641754 | 3 | 0 | 3 |
| NEU4 | KCNC2 | 0.637694 | 3 | 0 | 3 |
| NEU4 | SLC22A6 | 0.635869 | 4 | 0 | 4 |
| NEU4 | ADCY8 | 0.62548 | 3 | 0 | 3 |
| NEU4 | LINC00313 | 0.62492 | 3 | 0 | 3 |
| NEU4 | BCDIN3D-AS1 | 0.622752 | 3 | 0 | 3 |
| NEU4 | CHST13 | 0.621715 | 4 | 0 | 4 |
| NEU4 | IL17C | 0.620737 | 3 | 0 | 3 |
For details and further investigation, click here
