| Full name: ubiquitin specific peptidase 2 | Alias Symbol: UBP41 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 9099 | HGNC ID: HGNC:12618 | Ensembl Gene: ENSG00000036672 | OMIM ID: 604725 |
| Drug and gene relationship at DGIdb | |||
Expression of USP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP2 | 9099 | 229337_at | -0.7637 | 0.1323 | |
| GSE20347 | USP2 | 9099 | 207211_at | -0.0255 | 0.8137 | |
| GSE23400 | USP2 | 9099 | 207211_at | -0.1731 | 0.0001 | |
| GSE26886 | USP2 | 9099 | 230965_at | 0.1256 | 0.4130 | |
| GSE29001 | USP2 | 9099 | 207211_at | -0.2627 | 0.1166 | |
| GSE38129 | USP2 | 9099 | 207211_at | -0.0713 | 0.4166 | |
| GSE45670 | USP2 | 9099 | 230965_at | 0.0671 | 0.5788 | |
| GSE53622 | USP2 | 9099 | 67390 | -1.4982 | 0.0000 | |
| GSE53624 | USP2 | 9099 | 67390 | -1.6354 | 0.0000 | |
| GSE63941 | USP2 | 9099 | 230965_at | 0.1573 | 0.4464 | |
| GSE77861 | USP2 | 9099 | 230965_at | -0.1441 | 0.3186 | |
| GSE97050 | USP2 | 9099 | A_23_P24966 | -0.9433 | 0.2641 | |
| SRP007169 | USP2 | 9099 | RNAseq | -2.7790 | 0.0001 | |
| SRP064894 | USP2 | 9099 | RNAseq | -1.6298 | 0.0002 | |
| SRP133303 | USP2 | 9099 | RNAseq | -1.9073 | 0.0000 | |
| SRP159526 | USP2 | 9099 | RNAseq | -2.0184 | 0.0000 | |
| SRP193095 | USP2 | 9099 | RNAseq | -1.4072 | 0.0000 | |
| SRP219564 | USP2 | 9099 | RNAseq | -1.2125 | 0.1387 | |
| TCGA | USP2 | 9099 | RNAseq | -0.6906 | 0.0019 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by USP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP2 | 9099 | 1 | 11 | 18 | |
| GSE20123 | USP2 | 9099 | 1 | 11 | 18 | |
| GSE43470 | USP2 | 9099 | 2 | 8 | 33 | |
| GSE46452 | USP2 | 9099 | 3 | 26 | 30 | |
| GSE47630 | USP2 | 9099 | 2 | 19 | 19 | |
| GSE54993 | USP2 | 9099 | 10 | 0 | 60 | |
| GSE54994 | USP2 | 9099 | 5 | 19 | 29 | |
| GSE60625 | USP2 | 9099 | 0 | 3 | 8 | |
| GSE74703 | USP2 | 9099 | 1 | 5 | 30 | |
| GSE74704 | USP2 | 9099 | 0 | 7 | 13 | |
| TCGA | USP2 | 9099 | 4 | 51 | 41 |
Total number of gains: 29; Total number of losses: 160; Total Number of normals: 299.
Somatic mutations of USP2:
Generating mutation plots.
Highly correlated genes for USP2:
Showing top 20/1030 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP2 | KLF6 | 0.783554 | 4 | 0 | 4 |
| USP2 | OR6A2 | 0.761157 | 4 | 0 | 4 |
| USP2 | GALR1 | 0.754974 | 3 | 0 | 3 |
| USP2 | NPHS2 | 0.749794 | 4 | 0 | 4 |
| USP2 | UBE2D4 | 0.741804 | 4 | 0 | 4 |
| USP2 | CPA2 | 0.736608 | 3 | 0 | 3 |
| USP2 | EDA2R | 0.736606 | 5 | 0 | 5 |
| USP2 | PEBP4 | 0.731761 | 3 | 0 | 3 |
| USP2 | SLCO5A1 | 0.731328 | 3 | 0 | 3 |
| USP2 | CRHR2 | 0.724299 | 4 | 0 | 4 |
| USP2 | ZDHHC1 | 0.723327 | 3 | 0 | 3 |
| USP2 | ART1 | 0.710292 | 4 | 0 | 4 |
| USP2 | PDCD4 | 0.695529 | 3 | 0 | 3 |
| USP2 | USP53 | 0.695346 | 4 | 0 | 4 |
| USP2 | GDF10 | 0.68961 | 3 | 0 | 3 |
| USP2 | OR7C2 | 0.686385 | 5 | 0 | 4 |
| USP2 | LINC00563 | 0.68141 | 4 | 0 | 3 |
| USP2 | FEM1C | 0.68038 | 4 | 0 | 3 |
| USP2 | RBFADN | 0.677114 | 3 | 0 | 3 |
| USP2 | ADAM22 | 0.67601 | 5 | 0 | 5 |
For details and further investigation, click here
