| Full name: zona pellucida binding protein 2 | Alias Symbol: ZPBPL|MGC41930 | ||
| Type: protein-coding gene | Cytoband: 17q21.1 | ||
| Entrez ID: 124626 | HGNC ID: HGNC:20678 | Ensembl Gene: ENSG00000186075 | OMIM ID: 608499 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZPBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZPBP2 | 124626 | 231442_at | -0.1611 | 0.4319 | |
| GSE26886 | ZPBP2 | 124626 | 231442_at | -0.1655 | 0.1527 | |
| GSE45670 | ZPBP2 | 124626 | 231442_at | 0.1640 | 0.2179 | |
| GSE53622 | ZPBP2 | 124626 | 132391 | -0.0264 | 0.8696 | |
| GSE53624 | ZPBP2 | 124626 | 132391 | -0.1662 | 0.0915 | |
| GSE63941 | ZPBP2 | 124626 | 231442_at | -0.0279 | 0.9085 | |
| GSE77861 | ZPBP2 | 124626 | 231442_at | -0.0719 | 0.4515 | |
| SRP133303 | ZPBP2 | 124626 | RNAseq | 0.3111 | 0.0312 | |
| SRP193095 | ZPBP2 | 124626 | RNAseq | 0.3225 | 0.0311 | |
| TCGA | ZPBP2 | 124626 | RNAseq | 1.8510 | 0.3131 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZPBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZPBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZPBP2 | 124626 | 9 | 1 | 20 | |
| GSE20123 | ZPBP2 | 124626 | 9 | 1 | 20 | |
| GSE43470 | ZPBP2 | 124626 | 1 | 1 | 41 | |
| GSE46452 | ZPBP2 | 124626 | 34 | 0 | 25 | |
| GSE47630 | ZPBP2 | 124626 | 8 | 1 | 31 | |
| GSE54993 | ZPBP2 | 124626 | 3 | 4 | 63 | |
| GSE54994 | ZPBP2 | 124626 | 9 | 5 | 39 | |
| GSE60625 | ZPBP2 | 124626 | 4 | 0 | 7 | |
| GSE74703 | ZPBP2 | 124626 | 1 | 0 | 35 | |
| GSE74704 | ZPBP2 | 124626 | 5 | 1 | 14 | |
| TCGA | ZPBP2 | 124626 | 23 | 8 | 65 |
Total number of gains: 106; Total number of losses: 22; Total Number of normals: 360.
Somatic mutations of ZPBP2:
Generating mutation plots.
Highly correlated genes for ZPBP2:
Showing top 20/49 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZPBP2 | PSG3 | 0.680596 | 3 | 0 | 3 |
| ZPBP2 | KRTAP4-8 | 0.678253 | 3 | 0 | 3 |
| ZPBP2 | C4orf45 | 0.660672 | 3 | 0 | 3 |
| ZPBP2 | NAV2-AS5 | 0.650765 | 3 | 0 | 3 |
| ZPBP2 | FANCD2OS | 0.63023 | 3 | 0 | 3 |
| ZPBP2 | TCL6 | 0.62772 | 4 | 0 | 4 |
| ZPBP2 | GPLD1 | 0.624242 | 3 | 0 | 3 |
| ZPBP2 | SPNS3 | 0.620238 | 3 | 0 | 3 |
| ZPBP2 | TMEM190 | 0.617229 | 4 | 0 | 4 |
| ZPBP2 | OR4D2 | 0.612465 | 4 | 0 | 3 |
| ZPBP2 | OR1J4 | 0.603457 | 3 | 0 | 3 |
| ZPBP2 | ANHX | 0.599714 | 3 | 0 | 3 |
| ZPBP2 | DMRT3 | 0.594875 | 3 | 0 | 3 |
| ZPBP2 | IL17RC | 0.592791 | 3 | 0 | 3 |
| ZPBP2 | NYAP2 | 0.592282 | 4 | 0 | 3 |
| ZPBP2 | RS1 | 0.590003 | 3 | 0 | 3 |
| ZPBP2 | ADIG | 0.580091 | 3 | 0 | 3 |
| ZPBP2 | MUC7 | 0.575152 | 3 | 0 | 3 |
| ZPBP2 | LILRA2 | 0.573055 | 3 | 0 | 3 |
| ZPBP2 | TMEM222 | 0.570222 | 3 | 0 | 3 |
For details and further investigation, click here
