| Full name: transmembrane protein 222 | Alias Symbol: DKFZP564D0478 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 84065 | HGNC ID: HGNC:25363 | Ensembl Gene: ENSG00000186501 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM222:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM222 | 84065 | 52078_at | -0.0741 | 0.7667 | |
| GSE20347 | TMEM222 | 84065 | 52078_at | -0.1859 | 0.0162 | |
| GSE23400 | TMEM222 | 84065 | 52078_at | -0.0809 | 0.0402 | |
| GSE26886 | TMEM222 | 84065 | 52078_at | -0.2446 | 0.1151 | |
| GSE29001 | TMEM222 | 84065 | 52078_at | -0.1643 | 0.4055 | |
| GSE38129 | TMEM222 | 84065 | 52078_at | -0.1541 | 0.0082 | |
| GSE45670 | TMEM222 | 84065 | 52078_at | 0.0314 | 0.7643 | |
| GSE53622 | TMEM222 | 84065 | 50337 | 0.0406 | 0.5740 | |
| GSE53624 | TMEM222 | 84065 | 35542 | -0.2489 | 0.0000 | |
| GSE63941 | TMEM222 | 84065 | 52078_at | 0.6142 | 0.0020 | |
| GSE77861 | TMEM222 | 84065 | 52078_at | -0.1061 | 0.5946 | |
| GSE97050 | TMEM222 | 84065 | A_33_P3259722 | -0.0436 | 0.8773 | |
| SRP007169 | TMEM222 | 84065 | RNAseq | -1.5125 | 0.0002 | |
| SRP008496 | TMEM222 | 84065 | RNAseq | -1.1365 | 0.0000 | |
| SRP064894 | TMEM222 | 84065 | RNAseq | 0.0055 | 0.9823 | |
| SRP133303 | TMEM222 | 84065 | RNAseq | -0.1536 | 0.3927 | |
| SRP159526 | TMEM222 | 84065 | RNAseq | -0.4752 | 0.1717 | |
| SRP193095 | TMEM222 | 84065 | RNAseq | -0.3295 | 0.0005 | |
| SRP219564 | TMEM222 | 84065 | RNAseq | -0.2483 | 0.3830 | |
| TCGA | TMEM222 | 84065 | RNAseq | -0.0874 | 0.1147 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TMEM222 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM222:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM222 | 84065 | 0 | 6 | 24 | |
| GSE20123 | TMEM222 | 84065 | 0 | 5 | 25 | |
| GSE43470 | TMEM222 | 84065 | 3 | 6 | 34 | |
| GSE46452 | TMEM222 | 84065 | 5 | 1 | 53 | |
| GSE47630 | TMEM222 | 84065 | 8 | 3 | 29 | |
| GSE54993 | TMEM222 | 84065 | 2 | 1 | 67 | |
| GSE54994 | TMEM222 | 84065 | 10 | 4 | 39 | |
| GSE60625 | TMEM222 | 84065 | 0 | 0 | 11 | |
| GSE74703 | TMEM222 | 84065 | 2 | 4 | 30 | |
| GSE74704 | TMEM222 | 84065 | 0 | 0 | 20 | |
| TCGA | TMEM222 | 84065 | 10 | 24 | 62 |
Total number of gains: 40; Total number of losses: 54; Total Number of normals: 394.
Somatic mutations of TMEM222:
Generating mutation plots.
Highly correlated genes for TMEM222:
Showing top 20/727 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM222 | KLHDC3 | 0.818155 | 3 | 0 | 3 |
| TMEM222 | TIMM23 | 0.78501 | 3 | 0 | 3 |
| TMEM222 | USP5 | 0.777346 | 3 | 0 | 3 |
| TMEM222 | GNAI2 | 0.773955 | 3 | 0 | 3 |
| TMEM222 | MAPRE3 | 0.76138 | 3 | 0 | 3 |
| TMEM222 | AATK | 0.750692 | 3 | 0 | 3 |
| TMEM222 | GHDC | 0.740773 | 3 | 0 | 3 |
| TMEM222 | GTPBP1 | 0.731647 | 3 | 0 | 3 |
| TMEM222 | SYMPK | 0.723239 | 3 | 0 | 3 |
| TMEM222 | ANGPTL6 | 0.722709 | 3 | 0 | 3 |
| TMEM222 | DEFB132 | 0.720147 | 3 | 0 | 3 |
| TMEM222 | KCND1 | 0.715815 | 3 | 0 | 3 |
| TMEM222 | ABCD2 | 0.709957 | 3 | 0 | 3 |
| TMEM222 | ZNF548 | 0.70523 | 3 | 0 | 3 |
| TMEM222 | COPE | 0.703325 | 4 | 0 | 3 |
| TMEM222 | CACNG6 | 0.703173 | 3 | 0 | 3 |
| TMEM222 | PKM | 0.703128 | 3 | 0 | 3 |
| TMEM222 | KDM5C | 0.702511 | 5 | 0 | 4 |
| TMEM222 | ERCC2 | 0.691057 | 4 | 0 | 4 |
| TMEM222 | TMEM214 | 0.685785 | 4 | 0 | 4 |
For details and further investigation, click here
