| Full name: doublesex and mab-3 related transcription factor 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p24.3 | ||
| Entrez ID: 58524 | HGNC ID: HGNC:13909 | Ensembl Gene: ENSG00000064218 | OMIM ID: 614754 |
| Drug and gene relationship at DGIdb | |||
Expression of DMRT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DMRT3 | 58524 | 233930_at | -0.0278 | 0.9246 | |
| GSE26886 | DMRT3 | 58524 | 233930_at | -0.0701 | 0.3409 | |
| GSE45670 | DMRT3 | 58524 | 233930_at | 0.0633 | 0.4607 | |
| GSE53622 | DMRT3 | 58524 | 56703 | 0.9471 | 0.0000 | |
| GSE53624 | DMRT3 | 58524 | 56703 | 1.0316 | 0.0000 | |
| GSE63941 | DMRT3 | 58524 | 233930_at | 0.0456 | 0.7950 | |
| GSE77861 | DMRT3 | 58524 | 233930_at | 0.0201 | 0.8809 | |
| GSE97050 | DMRT3 | 58524 | A_23_P157895 | 0.2487 | 0.2410 | |
| SRP159526 | DMRT3 | 58524 | RNAseq | 2.4122 | 0.0004 | |
| TCGA | DMRT3 | 58524 | RNAseq | 2.6600 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by DMRT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DMRT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DMRT3 | 58524 | 1 | 15 | 14 | |
| GSE20123 | DMRT3 | 58524 | 1 | 14 | 15 | |
| GSE43470 | DMRT3 | 58524 | 3 | 14 | 26 | |
| GSE46452 | DMRT3 | 58524 | 2 | 23 | 34 | |
| GSE47630 | DMRT3 | 58524 | 4 | 27 | 9 | |
| GSE54993 | DMRT3 | 58524 | 6 | 3 | 61 | |
| GSE54994 | DMRT3 | 58524 | 9 | 18 | 26 | |
| GSE60625 | DMRT3 | 58524 | 0 | 2 | 9 | |
| GSE74703 | DMRT3 | 58524 | 3 | 10 | 23 | |
| GSE74704 | DMRT3 | 58524 | 0 | 12 | 8 | |
| TCGA | DMRT3 | 58524 | 13 | 51 | 32 |
Total number of gains: 42; Total number of losses: 189; Total Number of normals: 257.
Somatic mutations of DMRT3:
Generating mutation plots.
Highly correlated genes for DMRT3:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DMRT3 | MRPL52 | 0.671578 | 3 | 0 | 3 |
| DMRT3 | ST8SIA2 | 0.643588 | 3 | 0 | 3 |
| DMRT3 | NOVA2 | 0.638574 | 4 | 0 | 3 |
| DMRT3 | SSTR3 | 0.632159 | 3 | 0 | 3 |
| DMRT3 | GLI4 | 0.604966 | 4 | 0 | 3 |
| DMRT3 | AVPR1B | 0.596238 | 3 | 0 | 3 |
| DMRT3 | ZPBP2 | 0.594875 | 3 | 0 | 3 |
| DMRT3 | NKAIN1 | 0.593261 | 3 | 0 | 3 |
| DMRT3 | UTS2R | 0.581883 | 3 | 0 | 3 |
| DMRT3 | TMEM106A | 0.578237 | 5 | 0 | 4 |
| DMRT3 | DMRT2 | 0.573045 | 4 | 0 | 3 |
| DMRT3 | R3HDM4 | 0.561008 | 3 | 0 | 3 |
| DMRT3 | TUBB3 | 0.552905 | 4 | 0 | 3 |
| DMRT3 | EGLN3 | 0.548509 | 3 | 0 | 3 |
| DMRT3 | SEMA6B | 0.535423 | 4 | 0 | 3 |
| DMRT3 | GLP1R | 0.533272 | 3 | 0 | 3 |
| DMRT3 | AHSP | 0.527573 | 4 | 0 | 3 |
| DMRT3 | GPR156 | 0.52134 | 5 | 0 | 3 |
| DMRT3 | DNAH17-AS1 | 0.517815 | 3 | 0 | 3 |
| DMRT3 | DLGAP2-AS1 | 0.512721 | 4 | 0 | 3 |
For details and further investigation, click here
