| Full name: leukocyte immunoglobulin like receptor A2 | Alias Symbol: LIR-7|ILT1|CD85h|LIR7 | ||
| Type: protein-coding gene | Cytoband: 19q13.4 | ||
| Entrez ID: 11027 | HGNC ID: HGNC:6603 | Ensembl Gene: ENSG00000239998 | OMIM ID: 604812 |
| Drug and gene relationship at DGIdb | |||
LILRA2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04380 | Osteoclast differentiation |
Expression of LILRA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LILRA2 | 11027 | 211101_x_at | -0.0572 | 0.8976 | |
| GSE20347 | LILRA2 | 11027 | 211101_x_at | -0.1889 | 0.0229 | |
| GSE23400 | LILRA2 | 11027 | 211100_x_at | -0.0848 | 0.0171 | |
| GSE26886 | LILRA2 | 11027 | 211101_x_at | -0.3048 | 0.0325 | |
| GSE29001 | LILRA2 | 11027 | 211101_x_at | -0.3140 | 0.0047 | |
| GSE38129 | LILRA2 | 11027 | 211101_x_at | -0.2274 | 0.0005 | |
| GSE45670 | LILRA2 | 11027 | 211101_x_at | 0.0662 | 0.5249 | |
| GSE63941 | LILRA2 | 11027 | 211101_x_at | 0.1915 | 0.2069 | |
| GSE77861 | LILRA2 | 11027 | 211100_x_at | -0.1539 | 0.0907 | |
| GSE97050 | LILRA2 | 11027 | A_23_P142205 | 0.8628 | 0.1590 | |
| SRP007169 | LILRA2 | 11027 | RNAseq | 0.7312 | 0.3808 | |
| SRP064894 | LILRA2 | 11027 | RNAseq | 0.9128 | 0.0305 | |
| SRP133303 | LILRA2 | 11027 | RNAseq | 0.0912 | 0.5312 | |
| SRP159526 | LILRA2 | 11027 | RNAseq | 0.3391 | 0.6553 | |
| SRP193095 | LILRA2 | 11027 | RNAseq | 0.4735 | 0.0065 | |
| SRP219564 | LILRA2 | 11027 | RNAseq | 0.5657 | 0.5126 | |
| TCGA | LILRA2 | 11027 | RNAseq | -0.2020 | 0.5822 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LILRA2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LILRA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LILRA2 | 11027 | 3 | 4 | 23 | |
| GSE20123 | LILRA2 | 11027 | 3 | 3 | 24 | |
| GSE43470 | LILRA2 | 11027 | 2 | 11 | 30 | |
| GSE46452 | LILRA2 | 11027 | 45 | 1 | 13 | |
| GSE47630 | LILRA2 | 11027 | 8 | 6 | 26 | |
| GSE54993 | LILRA2 | 11027 | 17 | 4 | 49 | |
| GSE54994 | LILRA2 | 11027 | 4 | 13 | 36 | |
| GSE60625 | LILRA2 | 11027 | 9 | 0 | 2 | |
| GSE74703 | LILRA2 | 11027 | 2 | 7 | 27 | |
| GSE74704 | LILRA2 | 11027 | 3 | 1 | 16 | |
| TCGA | LILRA2 | 11027 | 19 | 14 | 63 |
Total number of gains: 115; Total number of losses: 64; Total Number of normals: 309.
Somatic mutations of LILRA2:
Generating mutation plots.
Highly correlated genes for LILRA2:
Showing top 20/868 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LILRA2 | PRELID1 | 0.74143 | 3 | 0 | 3 |
| LILRA2 | MPV17L | 0.727346 | 3 | 0 | 3 |
| LILRA2 | TMSB4Y | 0.719897 | 3 | 0 | 3 |
| LILRA2 | POLN | 0.719311 | 3 | 0 | 3 |
| LILRA2 | APEH | 0.713424 | 3 | 0 | 3 |
| LILRA2 | C11orf68 | 0.711762 | 3 | 0 | 3 |
| LILRA2 | RFTN2 | 0.708802 | 3 | 0 | 3 |
| LILRA2 | SIGLEC1 | 0.707037 | 3 | 0 | 3 |
| LILRA2 | HVCN1 | 0.706774 | 3 | 0 | 3 |
| LILRA2 | TPM3 | 0.702298 | 3 | 0 | 3 |
| LILRA2 | GSX1 | 0.700215 | 3 | 0 | 3 |
| LILRA2 | RAB37 | 0.698831 | 3 | 0 | 3 |
| LILRA2 | GNAI3 | 0.692677 | 3 | 0 | 3 |
| LILRA2 | ARPC2 | 0.690802 | 4 | 0 | 4 |
| LILRA2 | STX11 | 0.688534 | 3 | 0 | 3 |
| LILRA2 | MKNK1-AS1 | 0.688387 | 3 | 0 | 3 |
| LILRA2 | PRADC1 | 0.687918 | 3 | 0 | 3 |
| LILRA2 | TMC2 | 0.686789 | 4 | 0 | 4 |
| LILRA2 | CLC | 0.677865 | 3 | 0 | 3 |
| LILRA2 | CSNK2B | 0.677167 | 4 | 0 | 4 |
For details and further investigation, click here
