| Full name: ATP binding cassette subfamily A member 3 | Alias Symbol: ABC-C|EST111653|LBM180 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 21 | HGNC ID: HGNC:33 | Ensembl Gene: ENSG00000167972 | OMIM ID: 601615 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCA3 | 21 | 204343_at | -0.4611 | 0.2148 | |
| GSE20347 | ABCA3 | 21 | 204343_at | -0.0796 | 0.5710 | |
| GSE23400 | ABCA3 | 21 | 204343_at | -0.2119 | 0.0172 | |
| GSE26886 | ABCA3 | 21 | 204343_at | 0.4507 | 0.0804 | |
| GSE29001 | ABCA3 | 21 | 204343_at | 0.0095 | 0.9814 | |
| GSE38129 | ABCA3 | 21 | 204343_at | -0.2134 | 0.1381 | |
| GSE45670 | ABCA3 | 21 | 204343_at | -0.4374 | 0.0010 | |
| GSE53622 | ABCA3 | 21 | 12939 | -0.7506 | 0.0004 | |
| GSE53624 | ABCA3 | 21 | 12939 | -0.8028 | 0.0000 | |
| GSE63941 | ABCA3 | 21 | 204343_at | -0.0870 | 0.7742 | |
| GSE77861 | ABCA3 | 21 | 204343_at | -0.1233 | 0.5253 | |
| GSE97050 | ABCA3 | 21 | A_23_P140876 | -0.2542 | 0.7570 | |
| SRP064894 | ABCA3 | 21 | RNAseq | -0.1485 | 0.6898 | |
| SRP133303 | ABCA3 | 21 | RNAseq | -0.7276 | 0.0371 | |
| SRP159526 | ABCA3 | 21 | RNAseq | 0.2805 | 0.4419 | |
| SRP193095 | ABCA3 | 21 | RNAseq | 0.2578 | 0.3100 | |
| SRP219564 | ABCA3 | 21 | RNAseq | -0.1740 | 0.8155 | |
| TCGA | ABCA3 | 21 | RNAseq | -0.6924 | 0.0047 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABCA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCA3 | 21 | 5 | 5 | 20 | |
| GSE20123 | ABCA3 | 21 | 5 | 4 | 21 | |
| GSE43470 | ABCA3 | 21 | 4 | 7 | 32 | |
| GSE46452 | ABCA3 | 21 | 38 | 1 | 20 | |
| GSE47630 | ABCA3 | 21 | 13 | 6 | 21 | |
| GSE54993 | ABCA3 | 21 | 3 | 5 | 62 | |
| GSE54994 | ABCA3 | 21 | 5 | 9 | 39 | |
| GSE60625 | ABCA3 | 21 | 4 | 0 | 7 | |
| GSE74703 | ABCA3 | 21 | 4 | 5 | 27 | |
| GSE74704 | ABCA3 | 21 | 3 | 2 | 15 | |
| TCGA | ABCA3 | 21 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of ABCA3:
Generating mutation plots.
Highly correlated genes for ABCA3:
Showing top 20/584 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCA3 | CNIH3 | 0.789977 | 3 | 0 | 3 |
| ABCA3 | FAM13C | 0.779862 | 3 | 0 | 3 |
| ABCA3 | SLC25A27 | 0.764294 | 3 | 0 | 3 |
| ABCA3 | VRK3 | 0.761114 | 3 | 0 | 3 |
| ABCA3 | ID4 | 0.755794 | 3 | 0 | 3 |
| ABCA3 | CD99 | 0.752972 | 3 | 0 | 3 |
| ABCA3 | PDK2 | 0.740577 | 4 | 0 | 4 |
| ABCA3 | SEMA6D | 0.738741 | 3 | 0 | 3 |
| ABCA3 | MAPRE3 | 0.720667 | 3 | 0 | 3 |
| ABCA3 | IL13RA2 | 0.720363 | 3 | 0 | 3 |
| ABCA3 | ORAI3 | 0.72006 | 4 | 0 | 4 |
| ABCA3 | SNX25 | 0.713764 | 3 | 0 | 3 |
| ABCA3 | NLGN4Y | 0.71162 | 3 | 0 | 3 |
| ABCA3 | UFSP2 | 0.71021 | 4 | 0 | 4 |
| ABCA3 | TMEM129 | 0.705982 | 3 | 0 | 3 |
| ABCA3 | CUL4B | 0.705349 | 3 | 0 | 3 |
| ABCA3 | INSRR | 0.701671 | 3 | 0 | 3 |
| ABCA3 | C16orf86 | 0.700018 | 3 | 0 | 3 |
| ABCA3 | TEAD2 | 0.69943 | 4 | 0 | 3 |
| ABCA3 | RAB40AL | 0.695757 | 3 | 0 | 3 |
For details and further investigation, click here
