| Full name: sorting nexin 25 | Alias Symbol: SBBI31 | ||
| Type: protein-coding gene | Cytoband: 4q35.1 | ||
| Entrez ID: 83891 | HGNC ID: HGNC:21883 | Ensembl Gene: ENSG00000109762 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SNX25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX25 | 83891 | 227408_s_at | -0.3183 | 0.5485 | |
| GSE26886 | SNX25 | 83891 | 227408_s_at | 0.2633 | 0.3781 | |
| GSE45670 | SNX25 | 83891 | 227408_s_at | -0.2592 | 0.1091 | |
| GSE53622 | SNX25 | 83891 | 26771 | 0.0616 | 0.4230 | |
| GSE53624 | SNX25 | 83891 | 26771 | 0.1316 | 0.0442 | |
| GSE63941 | SNX25 | 83891 | 227408_s_at | -1.2712 | 0.0334 | |
| GSE77861 | SNX25 | 83891 | 227408_s_at | 0.1416 | 0.4350 | |
| GSE97050 | SNX25 | 83891 | A_23_P18641 | 0.2088 | 0.4731 | |
| SRP007169 | SNX25 | 83891 | RNAseq | 0.0627 | 0.8821 | |
| SRP008496 | SNX25 | 83891 | RNAseq | 0.1296 | 0.5932 | |
| SRP064894 | SNX25 | 83891 | RNAseq | -0.2883 | 0.1678 | |
| SRP133303 | SNX25 | 83891 | RNAseq | 0.2903 | 0.1108 | |
| SRP159526 | SNX25 | 83891 | RNAseq | 0.0655 | 0.8019 | |
| SRP193095 | SNX25 | 83891 | RNAseq | -0.0677 | 0.5150 | |
| SRP219564 | SNX25 | 83891 | RNAseq | -0.4218 | 0.1776 | |
| TCGA | SNX25 | 83891 | RNAseq | -0.1304 | 0.0333 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SNX25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX25 | 83891 | 3 | 11 | 16 | |
| GSE20123 | SNX25 | 83891 | 3 | 11 | 16 | |
| GSE43470 | SNX25 | 83891 | 1 | 13 | 29 | |
| GSE46452 | SNX25 | 83891 | 1 | 36 | 22 | |
| GSE47630 | SNX25 | 83891 | 0 | 22 | 18 | |
| GSE54993 | SNX25 | 83891 | 10 | 0 | 60 | |
| GSE54994 | SNX25 | 83891 | 2 | 12 | 39 | |
| GSE60625 | SNX25 | 83891 | 0 | 0 | 11 | |
| GSE74703 | SNX25 | 83891 | 1 | 10 | 25 | |
| GSE74704 | SNX25 | 83891 | 1 | 5 | 14 | |
| TCGA | SNX25 | 83891 | 11 | 32 | 53 |
Total number of gains: 33; Total number of losses: 152; Total Number of normals: 303.
Somatic mutations of SNX25:
Generating mutation plots.
Highly correlated genes for SNX25:
Showing top 20/444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX25 | S1PR1 | 0.840008 | 3 | 0 | 3 |
| SNX25 | IGFBP5 | 0.793039 | 3 | 0 | 3 |
| SNX25 | LRRK2 | 0.784472 | 3 | 0 | 3 |
| SNX25 | CD63 | 0.774535 | 3 | 0 | 3 |
| SNX25 | YPEL2 | 0.773287 | 3 | 0 | 3 |
| SNX25 | SVEP1 | 0.768219 | 3 | 0 | 3 |
| SNX25 | C11orf96 | 0.765485 | 3 | 0 | 3 |
| SNX25 | FIBIN | 0.762953 | 3 | 0 | 3 |
| SNX25 | RRAGA | 0.754608 | 3 | 0 | 3 |
| SNX25 | PDGFRA | 0.75412 | 3 | 0 | 3 |
| SNX25 | TMX4 | 0.749381 | 4 | 0 | 4 |
| SNX25 | NR2F2 | 0.74728 | 3 | 0 | 3 |
| SNX25 | FMO3 | 0.745273 | 3 | 0 | 3 |
| SNX25 | MAN1A2 | 0.734789 | 5 | 0 | 5 |
| SNX25 | TCF21 | 0.731942 | 3 | 0 | 3 |
| SNX25 | MSRB3 | 0.731695 | 3 | 0 | 3 |
| SNX25 | TRPV2 | 0.730689 | 3 | 0 | 3 |
| SNX25 | ENG | 0.729754 | 3 | 0 | 3 |
| SNX25 | AK3 | 0.729617 | 3 | 0 | 3 |
| SNX25 | IL33 | 0.728054 | 3 | 0 | 3 |
For details and further investigation, click here
