| Full name: ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | Alias Symbol: A3GALNT|A3GALT1 | ||
| Type: protein-coding gene | Cytoband: 9q34.2 | ||
| Entrez ID: 28 | HGNC ID: HGNC:79 | Ensembl Gene: ENSG00000175164 | OMIM ID: 110300 |
| Drug and gene relationship at DGIdb | |||
Expression of ABO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABO | 28 | 214504_at | -0.1660 | 0.4131 | |
| GSE20347 | ABO | 28 | 214504_at | -0.1136 | 0.2276 | |
| GSE23400 | ABO | 28 | 214504_at | -0.2551 | 0.0000 | |
| GSE26886 | ABO | 28 | 216929_x_at | -0.8913 | 0.0020 | |
| GSE29001 | ABO | 28 | 214504_at | -0.2024 | 0.1127 | |
| GSE38129 | ABO | 28 | 214504_at | -0.1084 | 0.0963 | |
| GSE45670 | ABO | 28 | 214504_at | 0.0632 | 0.5787 | |
| GSE53622 | ABO | 28 | 86003 | -1.3603 | 0.0000 | |
| GSE53624 | ABO | 28 | 86003 | -1.3090 | 0.0000 | |
| GSE63941 | ABO | 28 | 214504_at | 0.4701 | 0.1013 | |
| GSE77861 | ABO | 28 | 216929_x_at | -0.2281 | 0.1092 | |
| GSE97050 | ABO | 28 | A_33_P3266550 | -0.3158 | 0.5102 | |
| SRP008496 | ABO | 28 | RNAseq | -0.9961 | 0.2012 | |
| SRP064894 | ABO | 28 | RNAseq | -1.8935 | 0.0000 | |
| SRP133303 | ABO | 28 | RNAseq | -1.0204 | 0.0000 | |
| SRP159526 | ABO | 28 | RNAseq | -0.6892 | 0.2530 | |
| SRP193095 | ABO | 28 | RNAseq | -0.2135 | 0.2482 | |
| SRP219564 | ABO | 28 | RNAseq | -1.7519 | 0.0977 | |
| TCGA | ABO | 28 | RNAseq | -0.1767 | 0.6538 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ABO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABO | 28 | 5 | 7 | 18 | |
| GSE20123 | ABO | 28 | 5 | 7 | 18 | |
| GSE43470 | ABO | 28 | 4 | 7 | 32 | |
| GSE46452 | ABO | 28 | 6 | 13 | 40 | |
| GSE47630 | ABO | 28 | 4 | 15 | 21 | |
| GSE54993 | ABO | 28 | 3 | 3 | 64 | |
| GSE54994 | ABO | 28 | 12 | 9 | 32 | |
| GSE60625 | ABO | 28 | 0 | 0 | 11 | |
| GSE74703 | ABO | 28 | 4 | 5 | 27 | |
| GSE74704 | ABO | 28 | 3 | 5 | 12 | |
| TCGA | ABO | 28 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of ABO:
Generating mutation plots.
Highly correlated genes for ABO:
Showing top 20/754 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABO | SPX | 0.737028 | 3 | 0 | 3 |
| ABO | PRDX1 | 0.695018 | 3 | 0 | 3 |
| ABO | NIPAL1 | 0.691688 | 3 | 0 | 3 |
| ABO | PRSS58 | 0.677935 | 3 | 0 | 3 |
| ABO | LINC01192 | 0.675223 | 4 | 0 | 3 |
| ABO | EPS8L3 | 0.675056 | 3 | 0 | 3 |
| ABO | HHLA1 | 0.671453 | 3 | 0 | 3 |
| ABO | IL9R | 0.667701 | 4 | 0 | 4 |
| ABO | RORC | 0.659978 | 7 | 0 | 7 |
| ABO | ZNF835 | 0.654404 | 5 | 0 | 5 |
| ABO | RAB4B | 0.65082 | 5 | 0 | 4 |
| ABO | NLRP8 | 0.650452 | 4 | 0 | 3 |
| ABO | P2RX6 | 0.649326 | 4 | 0 | 4 |
| ABO | PSG7 | 0.648693 | 4 | 0 | 4 |
| ABO | SPPL2B | 0.648318 | 3 | 0 | 3 |
| ABO | SIAE | 0.646797 | 3 | 0 | 3 |
| ABO | KCNA4 | 0.64653 | 4 | 0 | 3 |
| ABO | AKAP7 | 0.641526 | 4 | 0 | 4 |
| ABO | CAMKV | 0.640374 | 4 | 0 | 4 |
| ABO | DUX1 | 0.636749 | 3 | 0 | 3 |
For details and further investigation, click here
