| Full name: EPS8 like 3 | Alias Symbol: FLJ21522|MGC16817 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 79574 | HGNC ID: HGNC:21297 | Ensembl Gene: ENSG00000198758 | OMIM ID: 614989 |
| Drug and gene relationship at DGIdb | |||
Expression of EPS8L3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPS8L3 | 79574 | 219404_at | -0.0564 | 0.8373 | |
| GSE20347 | EPS8L3 | 79574 | 219404_at | -0.1882 | 0.0091 | |
| GSE23400 | EPS8L3 | 79574 | 219404_at | -0.1884 | 0.0000 | |
| GSE26886 | EPS8L3 | 79574 | 219404_at | -0.0163 | 0.8894 | |
| GSE29001 | EPS8L3 | 79574 | 219404_at | -0.2799 | 0.1087 | |
| GSE38129 | EPS8L3 | 79574 | 219404_at | -0.3268 | 0.0029 | |
| GSE45670 | EPS8L3 | 79574 | 219404_at | -0.0839 | 0.3265 | |
| GSE53622 | EPS8L3 | 79574 | 19836 | -0.2079 | 0.4336 | |
| GSE53624 | EPS8L3 | 79574 | 19836 | -0.5523 | 0.0158 | |
| GSE63941 | EPS8L3 | 79574 | 219404_at | 0.3589 | 0.0053 | |
| GSE77861 | EPS8L3 | 79574 | 219404_at | -0.1386 | 0.0793 | |
| TCGA | EPS8L3 | 79574 | RNAseq | -4.5050 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EPS8L3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPS8L3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPS8L3 | 79574 | 0 | 12 | 18 | |
| GSE20123 | EPS8L3 | 79574 | 0 | 11 | 19 | |
| GSE43470 | EPS8L3 | 79574 | 0 | 9 | 34 | |
| GSE46452 | EPS8L3 | 79574 | 2 | 1 | 56 | |
| GSE47630 | EPS8L3 | 79574 | 9 | 5 | 26 | |
| GSE54993 | EPS8L3 | 79574 | 0 | 1 | 69 | |
| GSE54994 | EPS8L3 | 79574 | 7 | 4 | 42 | |
| GSE60625 | EPS8L3 | 79574 | 0 | 0 | 11 | |
| GSE74703 | EPS8L3 | 79574 | 0 | 7 | 29 | |
| GSE74704 | EPS8L3 | 79574 | 0 | 7 | 13 | |
| TCGA | EPS8L3 | 79574 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 83; Total Number of normals: 378.
Somatic mutations of EPS8L3:
Generating mutation plots.
Highly correlated genes for EPS8L3:
Showing top 20/1065 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPS8L3 | SLC22A13 | 0.739189 | 4 | 0 | 4 |
| EPS8L3 | C3orf36 | 0.730224 | 4 | 0 | 4 |
| EPS8L3 | EDA2R | 0.725256 | 4 | 0 | 4 |
| EPS8L3 | IL9R | 0.718837 | 4 | 0 | 4 |
| EPS8L3 | KLRG1 | 0.713506 | 4 | 0 | 4 |
| EPS8L3 | IL18BP | 0.710965 | 4 | 0 | 4 |
| EPS8L3 | CRX | 0.707858 | 5 | 0 | 5 |
| EPS8L3 | CA5B | 0.706334 | 3 | 0 | 3 |
| EPS8L3 | CNR2 | 0.704913 | 6 | 0 | 6 |
| EPS8L3 | KRTAP5-9 | 0.704486 | 4 | 0 | 4 |
| EPS8L3 | SERPINA4 | 0.702453 | 7 | 0 | 6 |
| EPS8L3 | UMOD | 0.700674 | 4 | 0 | 3 |
| EPS8L3 | MYO1A | 0.69503 | 7 | 0 | 7 |
| EPS8L3 | GC | 0.694899 | 5 | 0 | 4 |
| EPS8L3 | LGR5 | 0.689726 | 3 | 0 | 3 |
| EPS8L3 | ZNF835 | 0.689104 | 3 | 0 | 3 |
| EPS8L3 | SCTR | 0.688619 | 5 | 0 | 5 |
| EPS8L3 | CCDC7 | 0.687338 | 4 | 0 | 4 |
| EPS8L3 | HBQ1 | 0.685151 | 4 | 0 | 4 |
| EPS8L3 | TCP10L | 0.685102 | 5 | 0 | 5 |
For details and further investigation, click here
