| Full name: A-kinase anchoring protein 7 | Alias Symbol: AKAP18|AKAP15 | ||
| Type: protein-coding gene | Cytoband: 6q23.2 | ||
| Entrez ID: 9465 | HGNC ID: HGNC:377 | Ensembl Gene: ENSG00000118507 | OMIM ID: 604693 |
| Drug and gene relationship at DGIdb | |||
Expression of AKAP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AKAP7 | 9465 | 205771_s_at | -0.2542 | 0.5831 | |
| GSE20347 | AKAP7 | 9465 | 211172_x_at | -0.0433 | 0.6001 | |
| GSE23400 | AKAP7 | 9465 | 211172_x_at | -0.2106 | 0.0000 | |
| GSE26886 | AKAP7 | 9465 | 205771_s_at | -0.4628 | 0.4211 | |
| GSE29001 | AKAP7 | 9465 | 205771_s_at | -0.0507 | 0.9284 | |
| GSE38129 | AKAP7 | 9465 | 211172_x_at | -0.0997 | 0.2767 | |
| GSE45670 | AKAP7 | 9465 | 205771_s_at | -1.0205 | 0.0012 | |
| GSE53622 | AKAP7 | 9465 | 131180 | -0.5188 | 0.0000 | |
| GSE53624 | AKAP7 | 9465 | 131180 | -0.4864 | 0.0006 | |
| GSE63941 | AKAP7 | 9465 | 205771_s_at | -1.0829 | 0.1512 | |
| GSE77861 | AKAP7 | 9465 | 211172_x_at | -0.2117 | 0.0666 | |
| GSE97050 | AKAP7 | 9465 | A_23_P259594 | -0.2493 | 0.2858 | |
| SRP007169 | AKAP7 | 9465 | RNAseq | 0.1027 | 0.8422 | |
| SRP008496 | AKAP7 | 9465 | RNAseq | 0.0472 | 0.8836 | |
| SRP064894 | AKAP7 | 9465 | RNAseq | -0.3067 | 0.1165 | |
| SRP133303 | AKAP7 | 9465 | RNAseq | -0.3373 | 0.1528 | |
| SRP159526 | AKAP7 | 9465 | RNAseq | -0.2622 | 0.3638 | |
| SRP193095 | AKAP7 | 9465 | RNAseq | -0.7138 | 0.0067 | |
| SRP219564 | AKAP7 | 9465 | RNAseq | -0.5079 | 0.3670 | |
| TCGA | AKAP7 | 9465 | RNAseq | -0.2978 | 0.0023 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AKAP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AKAP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AKAP7 | 9465 | 2 | 5 | 23 | |
| GSE20123 | AKAP7 | 9465 | 2 | 4 | 24 | |
| GSE43470 | AKAP7 | 9465 | 5 | 0 | 38 | |
| GSE46452 | AKAP7 | 9465 | 2 | 11 | 46 | |
| GSE47630 | AKAP7 | 9465 | 9 | 4 | 27 | |
| GSE54993 | AKAP7 | 9465 | 3 | 3 | 64 | |
| GSE54994 | AKAP7 | 9465 | 8 | 8 | 37 | |
| GSE60625 | AKAP7 | 9465 | 0 | 1 | 10 | |
| GSE74703 | AKAP7 | 9465 | 4 | 0 | 32 | |
| GSE74704 | AKAP7 | 9465 | 1 | 1 | 18 | |
| TCGA | AKAP7 | 9465 | 11 | 18 | 67 |
Total number of gains: 47; Total number of losses: 55; Total Number of normals: 386.
Somatic mutations of AKAP7:
Generating mutation plots.
Highly correlated genes for AKAP7:
Showing top 20/671 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AKAP7 | MKRN2 | 0.764079 | 3 | 0 | 3 |
| AKAP7 | PHLDB1 | 0.751844 | 4 | 0 | 4 |
| AKAP7 | TRIM44 | 0.750646 | 3 | 0 | 3 |
| AKAP7 | CDC26 | 0.737849 | 3 | 0 | 3 |
| AKAP7 | MTAP | 0.730543 | 3 | 0 | 3 |
| AKAP7 | GNGT2 | 0.726319 | 3 | 0 | 3 |
| AKAP7 | FBXO3 | 0.710301 | 3 | 0 | 3 |
| AKAP7 | COMMD1 | 0.702802 | 4 | 0 | 4 |
| AKAP7 | TSSK2 | 0.699816 | 3 | 0 | 3 |
| AKAP7 | ZMAT4 | 0.699293 | 3 | 0 | 3 |
| AKAP7 | FOXN3 | 0.694324 | 3 | 0 | 3 |
| AKAP7 | MYH7 | 0.692116 | 3 | 0 | 3 |
| AKAP7 | GIMAP5 | 0.691869 | 3 | 0 | 3 |
| AKAP7 | ARGLU1 | 0.69144 | 3 | 0 | 3 |
| AKAP7 | RAB39B | 0.688082 | 4 | 0 | 3 |
| AKAP7 | SMO | 0.687114 | 3 | 0 | 3 |
| AKAP7 | CCL28 | 0.67954 | 3 | 0 | 3 |
| AKAP7 | CRBN | 0.679301 | 5 | 0 | 4 |
| AKAP7 | ZNF436 | 0.677443 | 3 | 0 | 3 |
| AKAP7 | RBMXL1 | 0.677011 | 3 | 0 | 3 |
For details and further investigation, click here
