| Full name: acyl-CoA synthetase family member 2 | Alias Symbol: FLJ20920|ACSMW | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 80221 | HGNC ID: HGNC:26101 | Ensembl Gene: ENSG00000167107 | OMIM ID: 610465 |
| Drug and gene relationship at DGIdb | |||
Expression of ACSF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACSF2 | 80221 | 218844_at | -0.1461 | 0.6692 | |
| GSE20347 | ACSF2 | 80221 | 218844_at | -0.3370 | 0.0186 | |
| GSE23400 | ACSF2 | 80221 | 218844_at | -0.2057 | 0.0060 | |
| GSE26886 | ACSF2 | 80221 | 218844_at | 0.0038 | 0.9909 | |
| GSE29001 | ACSF2 | 80221 | 218844_at | -0.0697 | 0.8319 | |
| GSE38129 | ACSF2 | 80221 | 218844_at | -0.3050 | 0.0382 | |
| GSE45670 | ACSF2 | 80221 | 218844_at | -0.1376 | 0.4295 | |
| GSE53622 | ACSF2 | 80221 | 113592 | -0.2883 | 0.0438 | |
| GSE53624 | ACSF2 | 80221 | 113592 | -0.4068 | 0.0001 | |
| GSE63941 | ACSF2 | 80221 | 218844_at | 0.3521 | 0.5163 | |
| GSE77861 | ACSF2 | 80221 | 218844_at | -0.4230 | 0.0700 | |
| GSE97050 | ACSF2 | 80221 | A_23_P4190 | 0.3061 | 0.3547 | |
| SRP007169 | ACSF2 | 80221 | RNAseq | -0.6828 | 0.1773 | |
| SRP008496 | ACSF2 | 80221 | RNAseq | -0.0195 | 0.9678 | |
| SRP064894 | ACSF2 | 80221 | RNAseq | -0.0295 | 0.9109 | |
| SRP133303 | ACSF2 | 80221 | RNAseq | -0.2291 | 0.3750 | |
| SRP159526 | ACSF2 | 80221 | RNAseq | 0.2817 | 0.6755 | |
| SRP193095 | ACSF2 | 80221 | RNAseq | -0.6028 | 0.0065 | |
| TCGA | ACSF2 | 80221 | RNAseq | -0.4632 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACSF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACSF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACSF2 | 80221 | 5 | 2 | 23 | |
| GSE20123 | ACSF2 | 80221 | 5 | 2 | 23 | |
| GSE43470 | ACSF2 | 80221 | 3 | 2 | 38 | |
| GSE46452 | ACSF2 | 80221 | 32 | 0 | 27 | |
| GSE47630 | ACSF2 | 80221 | 9 | 0 | 31 | |
| GSE54993 | ACSF2 | 80221 | 2 | 4 | 64 | |
| GSE54994 | ACSF2 | 80221 | 9 | 6 | 38 | |
| GSE60625 | ACSF2 | 80221 | 4 | 0 | 7 | |
| GSE74703 | ACSF2 | 80221 | 3 | 2 | 31 | |
| GSE74704 | ACSF2 | 80221 | 4 | 1 | 15 | |
| TCGA | ACSF2 | 80221 | 27 | 7 | 62 |
Total number of gains: 103; Total number of losses: 26; Total Number of normals: 359.
Somatic mutations of ACSF2:
Generating mutation plots.
Highly correlated genes for ACSF2:
Showing top 20/185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACSF2 | ADCK1 | 0.780183 | 3 | 0 | 3 |
| ACSF2 | ZNF784 | 0.768513 | 3 | 0 | 3 |
| ACSF2 | GAS6 | 0.765082 | 3 | 0 | 3 |
| ACSF2 | SH3BGRL3 | 0.737993 | 3 | 0 | 3 |
| ACSF2 | ZNF223 | 0.724005 | 3 | 0 | 3 |
| ACSF2 | PACSIN3 | 0.704592 | 3 | 0 | 3 |
| ACSF2 | THRAP3 | 0.695194 | 3 | 0 | 3 |
| ACSF2 | NHLH2 | 0.691431 | 3 | 0 | 3 |
| ACSF2 | KLHDC10 | 0.690058 | 3 | 0 | 3 |
| ACSF2 | CHID1 | 0.681949 | 3 | 0 | 3 |
| ACSF2 | PDCD4 | 0.678128 | 3 | 0 | 3 |
| ACSF2 | IL18BP | 0.677743 | 3 | 0 | 3 |
| ACSF2 | IDH3G | 0.673065 | 3 | 0 | 3 |
| ACSF2 | GBA2 | 0.672416 | 3 | 0 | 3 |
| ACSF2 | ZNF383 | 0.670538 | 3 | 0 | 3 |
| ACSF2 | SLC25A29 | 0.66814 | 3 | 0 | 3 |
| ACSF2 | RPL32 | 0.667185 | 4 | 0 | 3 |
| ACSF2 | SLC25A27 | 0.664903 | 3 | 0 | 3 |
| ACSF2 | AP4S1 | 0.657759 | 3 | 0 | 3 |
| ACSF2 | CIDEC | 0.654337 | 3 | 0 | 3 |
For details and further investigation, click here
