| Full name: SH3 domain binding glutamate rich protein like 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 83442 | HGNC ID: HGNC:15568 | Ensembl Gene: ENSG00000142669 | OMIM ID: 615679 |
| Drug and gene relationship at DGIdb | |||
Expression of SH3BGRL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SH3BGRL3 | 83442 | 221269_s_at | -0.0678 | 0.9307 | |
| GSE20347 | SH3BGRL3 | 83442 | 221269_s_at | -1.0613 | 0.0000 | |
| GSE23400 | SH3BGRL3 | 83442 | 221269_s_at | -0.3715 | 0.0018 | |
| GSE26886 | SH3BGRL3 | 83442 | 221269_s_at | -0.6489 | 0.0442 | |
| GSE29001 | SH3BGRL3 | 83442 | 221269_s_at | -1.0385 | 0.0281 | |
| GSE38129 | SH3BGRL3 | 83442 | 221269_s_at | -0.5745 | 0.0058 | |
| GSE45670 | SH3BGRL3 | 83442 | 221269_s_at | -0.0053 | 0.9844 | |
| GSE53622 | SH3BGRL3 | 83442 | 11010 | -0.5375 | 0.0000 | |
| GSE53624 | SH3BGRL3 | 83442 | 11010 | -0.5899 | 0.0000 | |
| GSE63941 | SH3BGRL3 | 83442 | 221269_s_at | -0.0040 | 0.9960 | |
| GSE77861 | SH3BGRL3 | 83442 | 221269_s_at | -0.6623 | 0.0152 | |
| GSE97050 | SH3BGRL3 | 83442 | A_23_P126388 | 0.3452 | 0.4552 | |
| SRP007169 | SH3BGRL3 | 83442 | RNAseq | -2.1575 | 0.0000 | |
| SRP008496 | SH3BGRL3 | 83442 | RNAseq | -1.9068 | 0.0000 | |
| SRP064894 | SH3BGRL3 | 83442 | RNAseq | 0.0135 | 0.9631 | |
| SRP133303 | SH3BGRL3 | 83442 | RNAseq | -0.0548 | 0.7858 | |
| SRP159526 | SH3BGRL3 | 83442 | RNAseq | -0.9091 | 0.0019 | |
| SRP193095 | SH3BGRL3 | 83442 | RNAseq | -0.5987 | 0.0013 | |
| SRP219564 | SH3BGRL3 | 83442 | RNAseq | -0.1292 | 0.7729 | |
| TCGA | SH3BGRL3 | 83442 | RNAseq | 0.1256 | 0.0361 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SH3BGRL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SH3BGRL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SH3BGRL3 | 83442 | 0 | 6 | 24 | |
| GSE20123 | SH3BGRL3 | 83442 | 0 | 5 | 25 | |
| GSE43470 | SH3BGRL3 | 83442 | 2 | 6 | 35 | |
| GSE46452 | SH3BGRL3 | 83442 | 5 | 1 | 53 | |
| GSE47630 | SH3BGRL3 | 83442 | 8 | 3 | 29 | |
| GSE54993 | SH3BGRL3 | 83442 | 2 | 1 | 67 | |
| GSE54994 | SH3BGRL3 | 83442 | 10 | 4 | 39 | |
| GSE60625 | SH3BGRL3 | 83442 | 0 | 0 | 11 | |
| GSE74703 | SH3BGRL3 | 83442 | 1 | 4 | 31 | |
| GSE74704 | SH3BGRL3 | 83442 | 0 | 0 | 20 | |
| TCGA | SH3BGRL3 | 83442 | 9 | 24 | 63 |
Total number of gains: 37; Total number of losses: 54; Total Number of normals: 397.
Somatic mutations of SH3BGRL3:
Generating mutation plots.
Highly correlated genes for SH3BGRL3:
Showing top 20/1215 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SH3BGRL3 | PRELID1 | 0.778572 | 4 | 0 | 4 |
| SH3BGRL3 | PHF23 | 0.774513 | 3 | 0 | 3 |
| SH3BGRL3 | ACSF2 | 0.737993 | 3 | 0 | 3 |
| SH3BGRL3 | CERS3 | 0.720215 | 4 | 0 | 4 |
| SH3BGRL3 | RER1 | 0.719215 | 10 | 0 | 9 |
| SH3BGRL3 | RAB4B | 0.712126 | 3 | 0 | 3 |
| SH3BGRL3 | ORMDL2 | 0.708519 | 9 | 0 | 9 |
| SH3BGRL3 | NIPAL1 | 0.70838 | 3 | 0 | 3 |
| SH3BGRL3 | OTUB1 | 0.699045 | 3 | 0 | 3 |
| SH3BGRL3 | TPRN | 0.696052 | 3 | 0 | 3 |
| SH3BGRL3 | ELOVL1 | 0.695169 | 4 | 0 | 3 |
| SH3BGRL3 | ZFPL1 | 0.693293 | 3 | 0 | 3 |
| SH3BGRL3 | VPS53 | 0.692565 | 4 | 0 | 4 |
| SH3BGRL3 | FBXO10 | 0.69256 | 4 | 0 | 3 |
| SH3BGRL3 | GIPC1 | 0.690987 | 11 | 0 | 10 |
| SH3BGRL3 | ZDHHC5 | 0.687729 | 5 | 0 | 4 |
| SH3BGRL3 | CGN | 0.685655 | 3 | 0 | 3 |
| SH3BGRL3 | GRN | 0.685551 | 11 | 0 | 10 |
| SH3BGRL3 | RHOG | 0.684168 | 11 | 0 | 11 |
| SH3BGRL3 | HECW2 | 0.681914 | 5 | 0 | 4 |
For details and further investigation, click here
