ZNF784

 

Full name: zinc finger protein 784 Alias Symbol: MGC75238
Type: protein-coding gene Cytoband: 19q13.42
Entrez ID: 147808 HGNC ID: HGNC:33111 Ensembl Gene: ENSG00000179922 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of ZNF784:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF784 147808 228364_at 0.0282 0.9655
GSE26886 ZNF784 147808 228364_at -0.4129 0.0209
GSE45670 ZNF784 147808 228364_at 0.0036 0.9822
GSE53622 ZNF784 147808 9061 -0.0201 0.8075
GSE53624 ZNF784 147808 9061 -0.1483 0.0122
GSE63941 ZNF784 147808 228364_at -0.1007 0.7365
GSE77861 ZNF784 147808 228364_at -0.2255 0.1413
GSE97050 ZNF784 147808 A_33_P3230399 -0.1874 0.4467
SRP007169 ZNF784 147808 RNAseq -0.7779 0.1524
SRP064894 ZNF784 147808 RNAseq 0.3918 0.2686
SRP133303 ZNF784 147808 RNAseq -0.2389 0.2768
SRP159526 ZNF784 147808 RNAseq 0.1165 0.7687
SRP193095 ZNF784 147808 RNAseq -0.2739 0.0615
SRP219564 ZNF784 147808 RNAseq -0.5714 0.1549
TCGA ZNF784 147808 RNAseq -0.1690 0.0188

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ZNF784 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF784:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF784 147808 3 4 23
GSE20123 ZNF784 147808 3 3 24
GSE43470 ZNF784 147808 3 9 31
GSE46452 ZNF784 147808 45 1 13
GSE47630 ZNF784 147808 8 6 26
GSE54993 ZNF784 147808 17 4 49
GSE54994 ZNF784 147808 4 13 36
GSE60625 ZNF784 147808 9 0 2
GSE74703 ZNF784 147808 3 6 27
GSE74704 ZNF784 147808 3 1 16
TCGA ZNF784 147808 19 14 63

Total number of gains: 117; Total number of losses: 61; Total Number of normals: 310.  


 

Somatic mutations of ZNF784:

 

Generating mutation plots.

 

Highly correlated genes for ZNF784:

 

Showing top 20/162 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF784USP200.812006303
ZNF784ZBTB220.804383303
ZNF784LSM14A0.780278303
ZNF784CRADD0.774477303
ZNF784ACSF20.768513303
ZNF784C5orf510.767018303
ZNF784RGMB0.748663303
ZNF784TMEM2180.740904303
ZNF784CELF60.738999303
ZNF784NEK40.737857303
ZNF784KAT70.737687404
ZNF784TSPO0.736832303
ZNF784UBE2NL0.731933303
ZNF784POLDIP30.728778303
ZNF784SELENBP10.728574404
ZNF784SKI0.728458303
ZNF784NPRL20.727102303
ZNF784APPL10.722335303
ZNF784RPRD20.717615303
ZNF784ZKSCAN10.713288303

For details and further investigation, click here