| Full name: kelch domain containing 10 | Alias Symbol: KIAA0265|slim | ||
| Type: protein-coding gene | Cytoband: 7q32.2 | ||
| Entrez ID: 23008 | HGNC ID: HGNC:22194 | Ensembl Gene: ENSG00000128607 | OMIM ID: 615152 |
| Drug and gene relationship at DGIdb | |||
Expression of KLHDC10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHDC10 | 23008 | 210111_s_at | -0.0023 | 0.9966 | |
| GSE20347 | KLHDC10 | 23008 | 210111_s_at | -0.4508 | 0.0024 | |
| GSE23400 | KLHDC10 | 23008 | 210111_s_at | -0.3137 | 0.0025 | |
| GSE26886 | KLHDC10 | 23008 | 210111_s_at | 0.1674 | 0.4776 | |
| GSE29001 | KLHDC10 | 23008 | 210111_s_at | -0.1328 | 0.4409 | |
| GSE38129 | KLHDC10 | 23008 | 210111_s_at | -0.3034 | 0.0073 | |
| GSE45670 | KLHDC10 | 23008 | 210111_s_at | -0.4410 | 0.0094 | |
| GSE53622 | KLHDC10 | 23008 | 136014 | -0.3598 | 0.0000 | |
| GSE53624 | KLHDC10 | 23008 | 32077 | -0.4874 | 0.0000 | |
| GSE63941 | KLHDC10 | 23008 | 210111_s_at | -0.9525 | 0.3132 | |
| GSE77861 | KLHDC10 | 23008 | 210111_s_at | -0.5163 | 0.0851 | |
| GSE97050 | KLHDC10 | 23008 | A_33_P3351765 | -0.3012 | 0.4352 | |
| SRP007169 | KLHDC10 | 23008 | RNAseq | -1.0351 | 0.0757 | |
| SRP008496 | KLHDC10 | 23008 | RNAseq | -0.6477 | 0.0241 | |
| SRP064894 | KLHDC10 | 23008 | RNAseq | -0.3855 | 0.0071 | |
| SRP133303 | KLHDC10 | 23008 | RNAseq | -0.1742 | 0.1233 | |
| SRP159526 | KLHDC10 | 23008 | RNAseq | -0.5743 | 0.0001 | |
| SRP193095 | KLHDC10 | 23008 | RNAseq | -0.5173 | 0.0000 | |
| SRP219564 | KLHDC10 | 23008 | RNAseq | -0.7329 | 0.0133 | |
| TCGA | KLHDC10 | 23008 | RNAseq | -0.2192 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLHDC10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHDC10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHDC10 | 23008 | 8 | 1 | 21 | |
| GSE20123 | KLHDC10 | 23008 | 8 | 1 | 21 | |
| GSE43470 | KLHDC10 | 23008 | 2 | 3 | 38 | |
| GSE46452 | KLHDC10 | 23008 | 7 | 2 | 50 | |
| GSE47630 | KLHDC10 | 23008 | 7 | 4 | 29 | |
| GSE54993 | KLHDC10 | 23008 | 3 | 5 | 62 | |
| GSE54994 | KLHDC10 | 23008 | 7 | 7 | 39 | |
| GSE60625 | KLHDC10 | 23008 | 0 | 0 | 11 | |
| GSE74703 | KLHDC10 | 23008 | 2 | 3 | 31 | |
| GSE74704 | KLHDC10 | 23008 | 4 | 1 | 15 | |
| TCGA | KLHDC10 | 23008 | 30 | 21 | 45 |
Total number of gains: 78; Total number of losses: 48; Total Number of normals: 362.
Somatic mutations of KLHDC10:
Generating mutation plots.
Highly correlated genes for KLHDC10:
Showing top 20/484 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHDC10 | RBM33 | 0.806109 | 3 | 0 | 3 |
| KLHDC10 | RBBP6 | 0.782009 | 3 | 0 | 3 |
| KLHDC10 | TSPAN3 | 0.780763 | 3 | 0 | 3 |
| KLHDC10 | TPRG1L | 0.780502 | 3 | 0 | 3 |
| KLHDC10 | THRAP3 | 0.766843 | 3 | 0 | 3 |
| KLHDC10 | FRMD6 | 0.754399 | 3 | 0 | 3 |
| KLHDC10 | PITHD1 | 0.735576 | 4 | 0 | 3 |
| KLHDC10 | RNASEH2B | 0.733997 | 3 | 0 | 3 |
| KLHDC10 | NUB1 | 0.729732 | 3 | 0 | 3 |
| KLHDC10 | SNX14 | 0.727614 | 3 | 0 | 3 |
| KLHDC10 | NANS | 0.724823 | 3 | 0 | 3 |
| KLHDC10 | C2CD2 | 0.718842 | 4 | 0 | 3 |
| KLHDC10 | LMBRD2 | 0.718779 | 4 | 0 | 4 |
| KLHDC10 | RFNG | 0.716523 | 3 | 0 | 3 |
| KLHDC10 | PPM1K | 0.714402 | 3 | 0 | 3 |
| KLHDC10 | PCBP3 | 0.71154 | 3 | 0 | 3 |
| KLHDC10 | BACE2 | 0.709881 | 4 | 0 | 3 |
| KLHDC10 | RBM20 | 0.705523 | 3 | 0 | 3 |
| KLHDC10 | AMBRA1 | 0.703676 | 3 | 0 | 3 |
| KLHDC10 | MRPL39 | 0.699469 | 3 | 0 | 3 |
For details and further investigation, click here
