| Full name: interleukin 18 binding protein | Alias Symbol: IL18BPa | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 10068 | HGNC ID: HGNC:5987 | Ensembl Gene: ENSG00000137496 | OMIM ID: 604113 |
| Drug and gene relationship at DGIdb | |||
Expression of IL18BP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL18BP | 10068 | 222868_s_at | 0.7095 | 0.2492 | |
| GSE20347 | IL18BP | 10068 | 219323_s_at | -0.1154 | 0.1616 | |
| GSE23400 | IL18BP | 10068 | 219323_s_at | -0.2452 | 0.0000 | |
| GSE26886 | IL18BP | 10068 | 219323_s_at | 0.4147 | 0.0028 | |
| GSE29001 | IL18BP | 10068 | 219323_s_at | -0.2055 | 0.2318 | |
| GSE38129 | IL18BP | 10068 | 219323_s_at | -0.1952 | 0.0092 | |
| GSE45670 | IL18BP | 10068 | 219323_s_at | -0.0180 | 0.8694 | |
| GSE53622 | IL18BP | 10068 | 50399 | 0.7724 | 0.0000 | |
| GSE53624 | IL18BP | 10068 | 50399 | 0.8332 | 0.0000 | |
| GSE63941 | IL18BP | 10068 | 219323_s_at | 0.0968 | 0.5165 | |
| GSE77861 | IL18BP | 10068 | 219323_s_at | -0.1240 | 0.3216 | |
| GSE97050 | IL18BP | 10068 | A_33_P3228322 | 1.1577 | 0.1453 | |
| SRP007169 | IL18BP | 10068 | RNAseq | 0.6323 | 0.3931 | |
| SRP064894 | IL18BP | 10068 | RNAseq | 1.4786 | 0.0000 | |
| SRP133303 | IL18BP | 10068 | RNAseq | 0.9824 | 0.0005 | |
| SRP159526 | IL18BP | 10068 | RNAseq | 0.1868 | 0.6036 | |
| SRP193095 | IL18BP | 10068 | RNAseq | 0.7744 | 0.0003 | |
| SRP219564 | IL18BP | 10068 | RNAseq | 1.6674 | 0.0013 | |
| TCGA | IL18BP | 10068 | RNAseq | 0.2275 | 0.0436 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by IL18BP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL18BP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL18BP | 10068 | 10 | 7 | 13 | |
| GSE20123 | IL18BP | 10068 | 10 | 7 | 13 | |
| GSE43470 | IL18BP | 10068 | 7 | 4 | 32 | |
| GSE46452 | IL18BP | 10068 | 13 | 16 | 30 | |
| GSE47630 | IL18BP | 10068 | 10 | 10 | 20 | |
| GSE54993 | IL18BP | 10068 | 7 | 3 | 60 | |
| GSE54994 | IL18BP | 10068 | 14 | 11 | 28 | |
| GSE60625 | IL18BP | 10068 | 0 | 7 | 4 | |
| GSE74703 | IL18BP | 10068 | 6 | 3 | 27 | |
| GSE74704 | IL18BP | 10068 | 7 | 4 | 9 | |
| TCGA | IL18BP | 10068 | 36 | 20 | 40 |
Total number of gains: 120; Total number of losses: 92; Total Number of normals: 276.
Somatic mutations of IL18BP:
Generating mutation plots.
Highly correlated genes for IL18BP:
Showing top 20/1011 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL18BP | HAVCR2 | 0.80331 | 3 | 0 | 3 |
| IL18BP | GRAPL | 0.801475 | 3 | 0 | 3 |
| IL18BP | ZNF581 | 0.777881 | 3 | 0 | 3 |
| IL18BP | ACAP1 | 0.776559 | 3 | 0 | 3 |
| IL18BP | ZNF358 | 0.758898 | 4 | 0 | 4 |
| IL18BP | TOMM5 | 0.753724 | 3 | 0 | 3 |
| IL18BP | CLCN7 | 0.750975 | 3 | 0 | 3 |
| IL18BP | BTN1A1 | 0.744791 | 5 | 0 | 5 |
| IL18BP | AP4S1 | 0.739502 | 7 | 0 | 7 |
| IL18BP | MBL2 | 0.73589 | 3 | 0 | 3 |
| IL18BP | CPA2 | 0.734574 | 3 | 0 | 3 |
| IL18BP | INHA | 0.734013 | 3 | 0 | 3 |
| IL18BP | CXXC1 | 0.729481 | 4 | 0 | 4 |
| IL18BP | FANCE | 0.724068 | 3 | 0 | 3 |
| IL18BP | GPR31 | 0.72367 | 5 | 0 | 5 |
| IL18BP | DDX60L | 0.721159 | 3 | 0 | 3 |
| IL18BP | BMP15 | 0.720856 | 4 | 0 | 4 |
| IL18BP | RABEP2 | 0.718729 | 4 | 0 | 3 |
| IL18BP | SRA1 | 0.718654 | 3 | 0 | 3 |
| IL18BP | ASH1L | 0.716312 | 3 | 0 | 3 |
For details and further investigation, click here
