| Full name: protein tyrosine phosphatase receptor type N2 | Alias Symbol: KIAA0387|phogrin|ICAAR|IA-2beta | ||
| Type: protein-coding gene | Cytoband: 7q36.3 | ||
| Entrez ID: 5799 | HGNC ID: HGNC:9677 | Ensembl Gene: ENSG00000155093 | OMIM ID: 601698 |
| Drug and gene relationship at DGIdb | |||
Expression of PTPRN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTPRN2 | 5799 | 203029_s_at | -0.7112 | 0.2735 | |
| GSE20347 | PTPRN2 | 5799 | 211534_x_at | -0.0779 | 0.4036 | |
| GSE23400 | PTPRN2 | 5799 | 211534_x_at | -0.2644 | 0.0000 | |
| GSE26886 | PTPRN2 | 5799 | 203029_s_at | 0.2478 | 0.3738 | |
| GSE29001 | PTPRN2 | 5799 | 211534_x_at | -0.2867 | 0.0855 | |
| GSE38129 | PTPRN2 | 5799 | 203029_s_at | -0.6178 | 0.0345 | |
| GSE45670 | PTPRN2 | 5799 | 203029_s_at | -1.5679 | 0.0000 | |
| GSE53622 | PTPRN2 | 5799 | 94529 | 0.0437 | 0.8411 | |
| GSE53624 | PTPRN2 | 5799 | 94529 | 1.3963 | 0.0000 | |
| GSE63941 | PTPRN2 | 5799 | 203029_s_at | -2.4707 | 0.0073 | |
| GSE77861 | PTPRN2 | 5799 | 211534_x_at | -0.2674 | 0.0482 | |
| GSE97050 | PTPRN2 | 5799 | A_32_P66804 | 0.2866 | 0.2941 | |
| SRP064894 | PTPRN2 | 5799 | RNAseq | -1.6144 | 0.0003 | |
| SRP133303 | PTPRN2 | 5799 | RNAseq | -1.9806 | 0.0000 | |
| SRP159526 | PTPRN2 | 5799 | RNAseq | -0.4759 | 0.3352 | |
| SRP219564 | PTPRN2 | 5799 | RNAseq | 0.0608 | 0.9272 | |
| TCGA | PTPRN2 | 5799 | RNAseq | -1.9031 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 5.
Survival by PTPRN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTPRN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTPRN2 | 5799 | 3 | 3 | 24 | |
| GSE20123 | PTPRN2 | 5799 | 2 | 3 | 25 | |
| GSE43470 | PTPRN2 | 5799 | 2 | 5 | 36 | |
| GSE46452 | PTPRN2 | 5799 | 7 | 2 | 50 | |
| GSE47630 | PTPRN2 | 5799 | 6 | 9 | 25 | |
| GSE54993 | PTPRN2 | 5799 | 3 | 3 | 64 | |
| GSE54994 | PTPRN2 | 5799 | 8 | 9 | 36 | |
| GSE60625 | PTPRN2 | 5799 | 0 | 0 | 11 | |
| GSE74703 | PTPRN2 | 5799 | 2 | 4 | 30 | |
| GSE74704 | PTPRN2 | 5799 | 1 | 3 | 16 | |
| TCGA | PTPRN2 | 5799 | 28 | 26 | 42 |
Total number of gains: 62; Total number of losses: 67; Total Number of normals: 359.
Somatic mutations of PTPRN2:
Generating mutation plots.
Highly correlated genes for PTPRN2:
Showing top 20/406 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTPRN2 | PDZD7 | 0.774473 | 6 | 0 | 6 |
| PTPRN2 | RGR | 0.773529 | 4 | 0 | 4 |
| PTPRN2 | PAX8 | 0.771077 | 6 | 0 | 6 |
| PTPRN2 | SLC5A4 | 0.766271 | 4 | 0 | 4 |
| PTPRN2 | RNF17 | 0.76203 | 4 | 0 | 4 |
| PTPRN2 | GP9 | 0.75826 | 5 | 0 | 5 |
| PTPRN2 | ASCL3 | 0.751154 | 4 | 0 | 4 |
| PTPRN2 | DMC1 | 0.745123 | 3 | 0 | 3 |
| PTPRN2 | ADAMTS7 | 0.741767 | 4 | 0 | 4 |
| PTPRN2 | PRAMEF12 | 0.736994 | 4 | 0 | 4 |
| PTPRN2 | SCNN1G | 0.733583 | 4 | 0 | 4 |
| PTPRN2 | RNF186 | 0.725653 | 5 | 0 | 5 |
| PTPRN2 | GALR3 | 0.725188 | 6 | 0 | 6 |
| PTPRN2 | ABCC2 | 0.725043 | 3 | 0 | 3 |
| PTPRN2 | MAGEA8 | 0.724935 | 3 | 0 | 3 |
| PTPRN2 | LAMA2 | 0.723917 | 4 | 0 | 4 |
| PTPRN2 | KRTAP5-9 | 0.717068 | 3 | 0 | 3 |
| PTPRN2 | ERN1 | 0.71469 | 4 | 0 | 4 |
| PTPRN2 | LIMD1 | 0.713172 | 5 | 0 | 4 |
| PTPRN2 | CYP2A7 | 0.710793 | 4 | 0 | 3 |
For details and further investigation, click here
