| Full name: actin related protein 1B | Alias Symbol: Arp1B | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 10120 | HGNC ID: HGNC:168 | Ensembl Gene: ENSG00000115073 | OMIM ID: 605144 |
| Drug and gene relationship at DGIdb | |||
Expression of ACTR1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTR1B | 10120 | 202135_s_at | 0.0853 | 0.8592 | |
| GSE20347 | ACTR1B | 10120 | 202135_s_at | -0.0807 | 0.4373 | |
| GSE23400 | ACTR1B | 10120 | 202135_s_at | -0.0703 | 0.1831 | |
| GSE26886 | ACTR1B | 10120 | 202135_s_at | 0.0550 | 0.7797 | |
| GSE29001 | ACTR1B | 10120 | 202135_s_at | -0.0749 | 0.6637 | |
| GSE38129 | ACTR1B | 10120 | 202135_s_at | -0.1102 | 0.1926 | |
| GSE45670 | ACTR1B | 10120 | 202135_s_at | -0.0936 | 0.4249 | |
| GSE53622 | ACTR1B | 10120 | 6417 | 0.0222 | 0.6853 | |
| GSE53624 | ACTR1B | 10120 | 6417 | 0.0490 | 0.3761 | |
| GSE63941 | ACTR1B | 10120 | 202135_s_at | 0.2373 | 0.5898 | |
| GSE77861 | ACTR1B | 10120 | 202135_s_at | -0.0532 | 0.7094 | |
| GSE97050 | ACTR1B | 10120 | A_23_P28279 | -0.1942 | 0.4081 | |
| SRP007169 | ACTR1B | 10120 | RNAseq | -0.3511 | 0.2782 | |
| SRP008496 | ACTR1B | 10120 | RNAseq | -0.2132 | 0.2743 | |
| SRP064894 | ACTR1B | 10120 | RNAseq | 0.1306 | 0.4487 | |
| SRP133303 | ACTR1B | 10120 | RNAseq | -0.1944 | 0.1920 | |
| SRP159526 | ACTR1B | 10120 | RNAseq | 0.5415 | 0.2565 | |
| SRP193095 | ACTR1B | 10120 | RNAseq | -0.2491 | 0.0075 | |
| SRP219564 | ACTR1B | 10120 | RNAseq | -0.3055 | 0.3784 | |
| TCGA | ACTR1B | 10120 | RNAseq | -0.1425 | 0.0066 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACTR1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTR1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTR1B | 10120 | 6 | 2 | 22 | |
| GSE20123 | ACTR1B | 10120 | 6 | 2 | 22 | |
| GSE43470 | ACTR1B | 10120 | 3 | 3 | 37 | |
| GSE46452 | ACTR1B | 10120 | 2 | 3 | 54 | |
| GSE47630 | ACTR1B | 10120 | 7 | 0 | 33 | |
| GSE54993 | ACTR1B | 10120 | 0 | 6 | 64 | |
| GSE54994 | ACTR1B | 10120 | 11 | 0 | 42 | |
| GSE60625 | ACTR1B | 10120 | 0 | 3 | 8 | |
| GSE74703 | ACTR1B | 10120 | 3 | 2 | 31 | |
| GSE74704 | ACTR1B | 10120 | 4 | 1 | 15 | |
| TCGA | ACTR1B | 10120 | 35 | 3 | 58 |
Total number of gains: 77; Total number of losses: 25; Total Number of normals: 386.
Somatic mutations of ACTR1B:
Generating mutation plots.
Highly correlated genes for ACTR1B:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTR1B | LRRC4B | 0.700197 | 3 | 0 | 3 |
| ACTR1B | GPR17 | 0.674762 | 3 | 0 | 3 |
| ACTR1B | MAGED2 | 0.673118 | 3 | 0 | 3 |
| ACTR1B | CIB3 | 0.662884 | 3 | 0 | 3 |
| ACTR1B | BAALC | 0.662574 | 3 | 0 | 3 |
| ACTR1B | PKDCC | 0.657443 | 4 | 0 | 3 |
| ACTR1B | DNAJB8 | 0.647878 | 3 | 0 | 3 |
| ACTR1B | FBXO17 | 0.647699 | 3 | 0 | 3 |
| ACTR1B | IVD | 0.640451 | 4 | 0 | 3 |
| ACTR1B | MAST3 | 0.637628 | 3 | 0 | 3 |
| ACTR1B | BCAT2 | 0.634832 | 4 | 0 | 3 |
| ACTR1B | TEF | 0.632876 | 4 | 0 | 3 |
| ACTR1B | DOK7 | 0.630891 | 3 | 0 | 3 |
| ACTR1B | CCDC102A | 0.629802 | 3 | 0 | 3 |
| ACTR1B | USP51 | 0.627391 | 4 | 0 | 3 |
| ACTR1B | HUNK | 0.62612 | 4 | 0 | 3 |
| ACTR1B | TRIM31 | 0.624099 | 3 | 0 | 3 |
| ACTR1B | EXOG | 0.616238 | 4 | 0 | 3 |
| ACTR1B | TATDN3 | 0.614215 | 4 | 0 | 3 |
| ACTR1B | RASL10B | 0.612543 | 3 | 0 | 3 |
For details and further investigation, click here
